DE69827805D1 - Verfahren und vorrichtung zur bestimmung des transformationspotentials von verbindungen. - Google Patents

Verfahren und vorrichtung zur bestimmung des transformationspotentials von verbindungen.

Info

Publication number
DE69827805D1
DE69827805D1 DE69827805T DE69827805T DE69827805D1 DE 69827805 D1 DE69827805 D1 DE 69827805D1 DE 69827805 T DE69827805 T DE 69827805T DE 69827805 T DE69827805 T DE 69827805T DE 69827805 D1 DE69827805 D1 DE 69827805D1
Authority
DE
Germany
Prior art keywords
apoptin
cells
cancer
normal
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69827805T
Other languages
English (en)
Other versions
DE69827805T2 (de
Inventor
Hubertus Noteborn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leadd BV
Original Assignee
Leadd BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leadd BV filed Critical Leadd BV
Publication of DE69827805D1 publication Critical patent/DE69827805D1/de
Application granted granted Critical
Publication of DE69827805T2 publication Critical patent/DE69827805T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • G01N33/5017—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity for testing neoplastic activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measurement Of Current Or Voltage (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DE69827805T 1997-08-12 1998-08-11 Verfahren und vorrichtung zur bestimmung des transformationspotentials von verbindungen. Expired - Lifetime DE69827805T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97202501 1997-08-12
EP97202501 1997-08-12
PCT/NL1998/000457 WO1999008108A1 (en) 1997-08-12 1998-08-11 Determining the transforming capability of agents

Publications (2)

Publication Number Publication Date
DE69827805D1 true DE69827805D1 (de) 2004-12-30
DE69827805T2 DE69827805T2 (de) 2005-12-15

Family

ID=8228640

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69827805T Expired - Lifetime DE69827805T2 (de) 1997-08-12 1998-08-11 Verfahren und vorrichtung zur bestimmung des transformationspotentials von verbindungen.

Country Status (16)

Country Link
US (1) US6528247B1 (de)
EP (1) EP1004021B1 (de)
JP (1) JP4287588B2 (de)
KR (1) KR20010022812A (de)
AT (1) ATE283478T1 (de)
AU (1) AU756587B2 (de)
BR (1) BR9811163A (de)
CA (1) CA2301401C (de)
CZ (1) CZ299874B6 (de)
DE (1) DE69827805T2 (de)
NO (1) NO326659B1 (de)
NZ (1) NZ502800A (de)
PL (1) PL196605B1 (de)
RU (1) RU2214598C2 (de)
SK (1) SK286235B6 (de)
WO (1) WO1999008108A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW514581B (en) * 1999-09-02 2002-12-21 Ciba Sc Holding Ag A method of protecting wood against light-induced degradation by treatment with an impregnation which penetrates the surface of the wood
EA005933B1 (ru) * 1999-09-02 2005-08-25 Леадд Б.В. Апоптин-ассоциированный белок
WO2001042461A2 (en) 1999-12-10 2001-06-14 Leadd B.V. Apoptin-associating protein
EP1199363A1 (de) 2000-10-20 2002-04-24 Leadd B.V. Phosphorylationsmodifikationen von Apoptin
PT1377667E (pt) * 2001-03-30 2009-03-13 Leadd Bv Proteínas de fusão para o tratamento específico de cancro e doenças auto-imunitárias
SE0302312D0 (sv) * 2002-10-04 2003-08-27 Forskarpatent I Syd Ab Peptide-based passive immunization therapy for treatment of atherosclerosis
AU2003904086A0 (en) 2003-08-04 2003-08-21 Cochlear Limited Implant battery short circuit protection
DK2658872T3 (da) 2010-12-27 2020-10-12 Apo T B V Polypeptid, der binder aberrerende celler og inducerer apoptose
WO2013048243A1 (en) 2011-09-29 2013-04-04 Apo-T B.V. Multi-specific binding molecules targeting aberrant cells
JP2015504895A (ja) 2012-01-13 2015-02-16 エーピーオー‐ティー ビー．ヴイ． 毒性部分を備える異常細胞拘束性免疫グロブリン

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9002008A (nl) 1990-09-12 1992-04-01 Stichting Centr Diergeneeskund Recombinant dna en rna en daarvan afgeleide produkten.
KR0162670B1 (ko) * 1991-01-15 1999-05-01 마르쿠 잘카넨 세포의 악성 전형을 나타내기 위한 조직 및 체액과 같은 생물학적 물질에서의 신데칸 내용물의 검출
EP0878546A1 (de) 1997-04-15 1998-11-18 Leadd B.V. Genabgabe-Vehikel die das Apoptosis VP2 inducierendes Protein, und/oder Apoptin exprimiert
CZ82692A3 (en) * 1992-03-19 1994-02-16 Prirodovedecka Fakulta Uk Method of testing cyctotoxicity and genotoxicity of chemicals
ATE241808T1 (de) 1995-06-07 2003-06-15 Leadd Bv Verwendungen von apoptin
JPH1015250A (ja) 1996-06-28 1998-01-20 Sega Enterp Ltd ゲーム装置
EP0921192A1 (de) * 1997-12-03 1999-06-09 Leadd B.V. Molekulen interagierend mit Apoptin
EP0927757A1 (de) * 1997-12-03 1999-07-07 Leadd B.V. Verfahren und Mitteln um Apoptose zu induzieren durch Interferenz mit Bip-ähnliche Proteine

Also Published As

Publication number Publication date
JP2001512829A (ja) 2001-08-28
CZ299874B6 (cs) 2008-12-17
ATE283478T1 (de) 2004-12-15
SK286235B6 (sk) 2008-06-06
NZ502800A (en) 2002-10-25
US6528247B1 (en) 2003-03-04
DE69827805T2 (de) 2005-12-15
PL338683A1 (en) 2000-11-20
WO1999008108A1 (en) 1999-02-18
AU8752998A (en) 1999-03-01
SK1902000A3 (en) 2000-11-07
EP1004021B1 (de) 2004-11-24
AU756587B2 (en) 2003-01-16
NO20000736L (no) 2000-04-11
JP4287588B2 (ja) 2009-07-01
CZ2000479A3 (cs) 2000-06-14
BR9811163A (pt) 2000-07-25
RU2214598C2 (ru) 2003-10-20
NO326659B1 (no) 2009-01-26
KR20010022812A (ko) 2001-03-26
EP1004021A1 (de) 2000-05-31
CA2301401C (en) 2008-10-21
CA2301401A1 (en) 1999-02-18
PL196605B1 (pl) 2008-01-31
NO20000736D0 (no) 2000-02-14

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