DE69825179D1 - Neues verfahren zur herstellung von cyklosporinderivaten - Google Patents

Neues verfahren zur herstellung von cyklosporinderivaten

Info

Publication number
DE69825179D1
DE69825179D1 DE69825179T DE69825179T DE69825179D1 DE 69825179 D1 DE69825179 D1 DE 69825179D1 DE 69825179 T DE69825179 T DE 69825179T DE 69825179 T DE69825179 T DE 69825179T DE 69825179 D1 DE69825179 D1 DE 69825179D1
Authority
DE
Germany
Prior art keywords
production
new method
cyclosporin derivatives
cyclosporin
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69825179T
Other languages
English (en)
Other versions
DE69825179T2 (de
Inventor
Guy Amouret
Antonio Guerreiro
Christian Viskov
Serge Mignani
Michel Evers
Jean-Claude Barriere
Georges Bashiardes
Jean-Christophe Carry
Bruno Filoche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Application granted granted Critical
Publication of DE69825179D1 publication Critical patent/DE69825179D1/de
Publication of DE69825179T2 publication Critical patent/DE69825179T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Cephalosporin Compounds (AREA)
DE69825179T 1997-12-19 1998-12-16 Neues verfahren zur herstellung von cyklosporinderivaten Expired - Lifetime DE69825179T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9716189A FR2772768B1 (fr) 1997-12-19 1997-12-19 Nouveau procede de preparation de derives de cyclosporine
FR9716189 1997-12-19
PCT/FR1998/002745 WO1999032512A1 (fr) 1997-12-19 1998-12-16 Nouveau procede de preparation de derives de cyclosporine

Publications (2)

Publication Number Publication Date
DE69825179D1 true DE69825179D1 (de) 2004-08-26
DE69825179T2 DE69825179T2 (de) 2005-09-08

Family

ID=9514865

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69825179T Expired - Lifetime DE69825179T2 (de) 1997-12-19 1998-12-16 Neues verfahren zur herstellung von cyklosporinderivaten

Country Status (15)

Country Link
EP (1) EP1040121B1 (de)
JP (1) JP3980269B2 (de)
AR (1) AR014136A1 (de)
AT (1) ATE271563T1 (de)
AU (1) AU1764099A (de)
DE (1) DE69825179T2 (de)
DK (1) DK1040121T3 (de)
ES (1) ES2224454T3 (de)
FR (1) FR2772768B1 (de)
MA (1) MA26585A1 (de)
PE (1) PE20020526A1 (de)
PT (1) PT1040121E (de)
TN (1) TNSN98231A1 (de)
WO (1) WO1999032512A1 (de)
ZA (1) ZA9811531B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2780061B1 (fr) * 1998-06-22 2001-09-07 Rhone Poulenc Rorer Sa Nouveau procede de preparation de derives de cyclosporine
KR100982466B1 (ko) * 2001-10-19 2010-09-16 이소테크니카 인코포레이티드 시클로스포린 유사체의 합성
KR20040039622A (ko) * 2002-11-04 2004-05-12 주식회사 엘지생활건강 모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제
US7196161B2 (en) 2004-10-01 2007-03-27 Scynexis Inc. 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
ATE498630T1 (de) 2005-09-30 2011-03-15 Scynexis Inc Arylalkyl- und heteroarylalkyl-derivate von cyclosporin a bei der behandlung und vorbeugung einer virusinfektion
US7754685B2 (en) 2005-09-30 2010-07-13 Scynexis, Inc. Methods and pharmaceutical compositions for the treatment and prevention of hepatitis C infection
EP2023918B1 (de) 2006-05-19 2011-03-23 Scynexis, Inc. Cyclosporins zur behandlung und vorbeugung von augenerkrankungen
US7576057B2 (en) 2006-11-20 2009-08-18 Scynexis, Inc. Cyclic peptides
US9090671B2 (en) 2008-06-06 2015-07-28 Scynexis, Inc. Macrocyclic peptides
WO2010076329A1 (en) 2008-12-31 2010-07-08 Scynexis, Inc. Derivatives of cyclosporin a
CA2763207A1 (en) 2009-05-27 2010-12-02 Allergan, Inc. Cyclosporin derivatives for treating inflammatory diseases and conditions
WO2011082289A1 (en) 2009-12-30 2011-07-07 Scynexis Inc. Cyclosporine analogues
US9175042B2 (en) * 2010-10-12 2015-11-03 Allergan, Inc. Cyclosporin analogs
PT2651965T (pt) 2010-12-15 2019-01-28 Contravir Pharmaceuticals Inc Moléculas analógas de ciclosporinas modificadas ao nivel dos aminoácidos 1 e 3
WO2020037530A1 (en) * 2018-08-22 2020-02-27 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Crystalline form of compound and uses thereof in medicine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0194972B1 (de) * 1985-03-11 1992-07-29 Sandoz Ag Cyclosporine
WO1997004005A2 (de) * 1995-07-17 1997-02-06 C-Chem Ag Cyclosporin-derivate mit anti-hiv-wirkung

Also Published As

Publication number Publication date
DE69825179T2 (de) 2005-09-08
FR2772768B1 (fr) 2000-01-14
EP1040121A1 (de) 2000-10-04
JP2002502803A (ja) 2002-01-29
PT1040121E (pt) 2004-11-30
TNSN98231A1 (fr) 2005-03-15
ES2224454T3 (es) 2005-03-01
FR2772768A1 (fr) 1999-06-25
DK1040121T3 (da) 2004-11-29
ZA9811531B (en) 1999-06-15
WO1999032512A1 (fr) 1999-07-01
PE20020526A1 (es) 2002-07-10
JP3980269B2 (ja) 2007-09-26
ATE271563T1 (de) 2004-08-15
AU1764099A (en) 1999-07-12
MA26585A1 (fr) 2004-12-20
EP1040121B1 (de) 2004-07-21
AR014136A1 (es) 2001-02-07

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS PHARMA S.A., ANTONY, FR

8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC