ATE271563T1 - Neues verfahren zur herstellung von cyklosporinderivaten - Google Patents

Neues verfahren zur herstellung von cyklosporinderivaten

Info

Publication number
ATE271563T1
ATE271563T1 AT98962475T AT98962475T ATE271563T1 AT E271563 T1 ATE271563 T1 AT E271563T1 AT 98962475 T AT98962475 T AT 98962475T AT 98962475 T AT98962475 T AT 98962475T AT E271563 T1 ATE271563 T1 AT E271563T1
Authority
AT
Austria
Prior art keywords
new process
cyclosporine derivatives
producing
producing cyclosporine
derivatives
Prior art date
Application number
AT98962475T
Other languages
English (en)
Inventor
Guy Amouret
Antonio Guerreiro
Christian Viskov
Serge Mignani
Michel Evers
Jean-Claude Barriere
Georges Bashiardes
Jean-Christophe Carry
Bruno Filoche
Original Assignee
Aventis Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma filed Critical Aventis Pharma
Application granted granted Critical
Publication of ATE271563T1 publication Critical patent/ATE271563T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • C07K7/645Cyclosporins; Related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Cephalosporin Compounds (AREA)
AT98962475T 1997-12-19 1998-12-16 Neues verfahren zur herstellung von cyklosporinderivaten ATE271563T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9716189A FR2772768B1 (fr) 1997-12-19 1997-12-19 Nouveau procede de preparation de derives de cyclosporine
PCT/FR1998/002745 WO1999032512A1 (fr) 1997-12-19 1998-12-16 Nouveau procede de preparation de derives de cyclosporine

Publications (1)

Publication Number Publication Date
ATE271563T1 true ATE271563T1 (de) 2004-08-15

Family

ID=9514865

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98962475T ATE271563T1 (de) 1997-12-19 1998-12-16 Neues verfahren zur herstellung von cyklosporinderivaten

Country Status (15)

Country Link
EP (1) EP1040121B1 (de)
JP (1) JP3980269B2 (de)
AR (1) AR014136A1 (de)
AT (1) ATE271563T1 (de)
AU (1) AU1764099A (de)
DE (1) DE69825179T2 (de)
DK (1) DK1040121T3 (de)
ES (1) ES2224454T3 (de)
FR (1) FR2772768B1 (de)
MA (1) MA26585A1 (de)
PE (1) PE20020526A1 (de)
PT (1) PT1040121E (de)
TN (1) TNSN98231A1 (de)
WO (1) WO1999032512A1 (de)
ZA (1) ZA9811531B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2780061B1 (fr) * 1998-06-22 2001-09-07 Rhone Poulenc Rorer Sa Nouveau procede de preparation de derives de cyclosporine
PL210795B1 (pl) 2001-10-19 2012-03-30 Isotechnika Inc Sposób wytwarzania mieszaniny ISATX247 wzbogaconej w izomer (E), sposób wytwarzania mieszaniny ISATX247 wzbogaconej w izomer (Z), sposób stereoselektywnej syntezy izomeru (E) ISATX247, sposób stereoselektywnej syntezy izomeru (Z) ISATX247 i sposób wytwarzania mieszaniny izomerów ISATX247
KR20040039622A (ko) * 2002-11-04 2004-05-12 주식회사 엘지생활건강 모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제
US7196161B2 (en) 2004-10-01 2007-03-27 Scynexis Inc. 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection
US8329658B2 (en) 2005-09-30 2012-12-11 Scynexis, Inc. Arylalkyl and heteroarylalkyl derivatives of cyclosporine A for the treatment and prevention of viral infection
WO2007041632A2 (en) 2005-09-30 2007-04-12 Scynexis, Inc. Methods and pharmaceutical compositions for the treatment and prevention of hepatitis c infection
US8188052B2 (en) 2006-05-19 2012-05-29 Scynexis, Inc. Method for the treatment and prevention of ocular disorders
WO2008069917A2 (en) 2006-11-20 2008-06-12 Scynexis, Inc. Novel cyclic peptides
WO2010002428A2 (en) 2008-06-06 2010-01-07 Scynexis, Inc. Novel macrocyclic peptides
US8536114B2 (en) 2008-12-31 2013-09-17 Scynexis, Inc. Macrocycles
JP2012528163A (ja) * 2009-05-27 2012-11-12 アラーガン、インコーポレイテッド 炎症性疾患および状態を処置するためのシクロスポリン誘導体
KR20120125610A (ko) 2009-12-30 2012-11-16 싸이넥시스, 인크. 시클로스포린 유사체
JP5805773B2 (ja) * 2010-10-12 2015-11-10 アラーガン、インコーポレイテッドAllergan,Incorporated シクロスポリンアナログ
DK2651965T3 (en) 2010-12-15 2019-02-18 Contravir Pharmaceuticals Inc CYCLOSPORIN ANALOGUAL MODULES MODIFIED BY AMINO ACID 1 AND 3
WO2020037530A1 (en) * 2018-08-22 2020-02-27 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Crystalline form of compound and uses thereof in medicine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0194972B1 (de) * 1985-03-11 1992-07-29 Sandoz Ag Cyclosporine
NZ315324A (en) * 1995-07-17 1999-10-28 Chem Ag C Cyclosporin derivatives with anti-hiv effect

Also Published As

Publication number Publication date
ZA9811531B (en) 1999-06-15
EP1040121B1 (de) 2004-07-21
PE20020526A1 (es) 2002-07-10
ES2224454T3 (es) 2005-03-01
PT1040121E (pt) 2004-11-30
MA26585A1 (fr) 2004-12-20
DE69825179D1 (de) 2004-08-26
FR2772768B1 (fr) 2000-01-14
DK1040121T3 (da) 2004-11-29
DE69825179T2 (de) 2005-09-08
JP3980269B2 (ja) 2007-09-26
AR014136A1 (es) 2001-02-07
EP1040121A1 (de) 2000-10-04
WO1999032512A1 (fr) 1999-07-01
AU1764099A (en) 1999-07-12
TNSN98231A1 (fr) 2005-03-15
JP2002502803A (ja) 2002-01-29
FR2772768A1 (fr) 1999-06-25

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