DE69818676D1 - Galaktomannanpolymere und borat enthaltende viskoelastische systeme mit regelbarer viskosität - Google Patents

Galaktomannanpolymere und borat enthaltende viskoelastische systeme mit regelbarer viskosität

Info

Publication number
DE69818676D1
DE69818676D1 DE69818676T DE69818676T DE69818676D1 DE 69818676 D1 DE69818676 D1 DE 69818676D1 DE 69818676 T DE69818676 T DE 69818676T DE 69818676 T DE69818676 T DE 69818676T DE 69818676 D1 DE69818676 D1 DE 69818676D1
Authority
DE
Germany
Prior art keywords
galactomanan
polymers
containing viscoelastic
borate containing
adjustable viscosity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69818676T
Other languages
English (en)
Other versions
DE69818676T2 (de
Inventor
Bahram Asgharian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Research LLC
Original Assignee
Alcon Manufacturing Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Manufacturing Ltd filed Critical Alcon Manufacturing Ltd
Publication of DE69818676D1 publication Critical patent/DE69818676D1/de
Application granted granted Critical
Publication of DE69818676T2 publication Critical patent/DE69818676T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
DE69818676T 1997-07-29 1998-07-17 Galaktomannanpolymere und borat enthaltende viskoelastische systeme mit regelbarer viskosität Expired - Lifetime DE69818676T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5430797P 1997-07-29 1997-07-29
US54307P 1997-07-29
PCT/US1998/014595 WO1999006070A1 (en) 1997-07-29 1998-07-17 Switchable viscoelastic systems containing galactomannan polymers and borate

Publications (2)

Publication Number Publication Date
DE69818676D1 true DE69818676D1 (de) 2003-11-06
DE69818676T2 DE69818676T2 (de) 2004-04-29

Family

ID=21990155

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69818676T Expired - Lifetime DE69818676T2 (de) 1997-07-29 1998-07-17 Galaktomannanpolymere und borat enthaltende viskoelastische systeme mit regelbarer viskosität

Country Status (14)

Country Link
US (1) US6495608B1 (de)
EP (1) EP0999854B1 (de)
JP (1) JP2001511460A (de)
AR (1) AR013273A1 (de)
AT (1) ATE250939T1 (de)
AU (1) AU8570498A (de)
DE (1) DE69818676T2 (de)
DK (1) DK0999854T3 (de)
ES (1) ES2209170T3 (de)
HK (1) HK1024623A1 (de)
PT (1) PT999854E (de)
TW (1) TWI221775B (de)
WO (1) WO1999006070A1 (de)
ZA (1) ZA986531B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001511460A (ja) 1997-07-29 2001-08-14 アルコン ラボラトリーズ インコーポレイテッド ガラクトマンナンポリマー及びホウ酸塩を含む切り替え可能粘弾性系
CN1229110C (zh) * 1997-07-29 2005-11-30 阿尔康实验室公司 含半乳甘露聚糖聚合物和硼酸盐的眼用组合物
EP1203808B1 (de) 1997-07-29 2004-09-29 Alcon Laboratories, Inc. Konditionierungslösungen für die Pflege von harten Kontaktlinsen
US20050129770A1 (en) * 2003-12-11 2005-06-16 Alcon, Inc. Ophthalmic compositions containing a PVA/borate gelling system
WO2005060933A1 (en) * 2003-12-11 2005-07-07 Alcon, Inc. Ophthalmic compositions containing a polysaccharide/borate gelling system
SE0401182D0 (sv) * 2004-05-05 2004-05-05 Q Med Ab Novel use of a viscoelastic composition
US20070059274A1 (en) * 2004-12-01 2007-03-15 Bahram Asgharian Ophthalmic compositions containing a PVA/borate gelling system
CA2722508C (en) 2008-04-26 2016-08-16 Alcon Research Ltd. Polymeric artificial tear system
BRPI1008654A2 (pt) * 2009-02-05 2016-03-08 Alcon Res Ltd processo para purificação de guar
TWI478730B (zh) 2009-12-03 2015-04-01 Alcon Res Ltd 眼科乳劑
US20170037303A1 (en) 2015-08-03 2017-02-09 Ecolab Usa Inc. Compositions and methods for delayed crosslinking in hydraulic fracturing fluids
WO2018013816A1 (en) 2016-07-15 2018-01-18 Ecolab USA, Inc. Compositions and methods for delayed crosslinking in hydraulic fracturing fluids
TW201938141A (zh) 2018-02-21 2019-10-01 瑞士商諾華公司 基於脂質的眼用乳劑
CN108578789B (zh) * 2018-05-25 2020-12-08 爱博诺德(北京)医疗科技股份有限公司 眼科粘弹剂
CN108671270A (zh) * 2018-05-25 2018-10-19 爱博诺德（北京）医疗科技有限公司 具有氧化还原特性的粘弹剂材料

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136178A (en) 1977-01-31 1979-01-23 American Home Products Corp. Locust bean gum therapeutic compositions
US4136177A (en) 1977-01-31 1979-01-23 American Home Products Corp. Xanthan gum therapeutic compositions
US4436730A (en) 1979-06-25 1984-03-13 Polymer Technology Corporation Ionic opthalmic cellulose polymer solutions
FR2588189B1 (fr) * 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
US5607698A (en) 1988-08-04 1997-03-04 Ciba-Geigy Corporation Method of preserving ophthalmic solution and compositions therefor
US5082579A (en) * 1990-01-16 1992-01-21 Bj Services Company Method and composition for delaying the gellation of borated galactomannans
US5160643A (en) * 1990-01-16 1992-11-03 Bj Services Company Method for delaying the gellation of borated galactomannans with a delay additive such as glyoxal
DE4026153A1 (de) * 1990-08-17 1992-02-20 Sebapharma Gmbh & Co Wundverband
US5273056A (en) 1992-06-12 1993-12-28 Alcon Laboratories, Inc. Use of combinations of viscoelastics during surgery
US5792103A (en) 1995-02-03 1998-08-11 Schwartz; Daniel M. Viscosurgical method and apparatus
US5827937A (en) 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
GB9603146D0 (en) 1996-02-15 1996-04-17 Innovative Tech Ltd Hydrogels
EP1203808B1 (de) * 1997-07-29 2004-09-29 Alcon Laboratories, Inc. Konditionierungslösungen für die Pflege von harten Kontaktlinsen
JP2001511460A (ja) 1997-07-29 2001-08-14 アルコン ラボラトリーズ インコーポレイテッド ガラクトマンナンポリマー及びホウ酸塩を含む切り替え可能粘弾性系

Also Published As

Publication number Publication date
DK0999854T3 (da) 2004-02-09
TWI221775B (en) 2004-10-11
ZA986531B (en) 1999-02-05
US6495608B1 (en) 2002-12-17
EP0999854A1 (de) 2000-05-17
PT999854E (pt) 2003-12-31
HK1024623A1 (en) 2000-10-20
EP0999854B1 (de) 2003-10-01
WO1999006070A1 (en) 1999-02-11
WO1999006070A9 (en) 1999-04-29
DE69818676T2 (de) 2004-04-29
AR013273A1 (es) 2000-12-13
ATE250939T1 (de) 2003-10-15
ES2209170T3 (es) 2004-06-16
JP2001511460A (ja) 2001-08-14
AU8570498A (en) 1999-02-22

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