DE69814884D1 - Hepatitis b virale polypeptide - Google Patents

Hepatitis b virale polypeptide

Info

Publication number
DE69814884D1
DE69814884D1 DE69814884T DE69814884T DE69814884D1 DE 69814884 D1 DE69814884 D1 DE 69814884D1 DE 69814884 T DE69814884 T DE 69814884T DE 69814884 T DE69814884 T DE 69814884T DE 69814884 D1 DE69814884 D1 DE 69814884D1
Authority
DE
Germany
Prior art keywords
hepatitis
fragment
viral polypeptide
polypeptide
hbv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69814884T
Other languages
English (en)
Other versions
DE69814884T2 (de
Inventor
Neville Chatfield
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celltech Pharma Europe Ltd
Original Assignee
Celltech Pharma Europe Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celltech Pharma Europe Ltd filed Critical Celltech Pharma Europe Ltd
Publication of DE69814884D1 publication Critical patent/DE69814884D1/de
Application granted granted Critical
Publication of DE69814884T2 publication Critical patent/DE69814884T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69814884T 1997-09-19 1998-09-21 Hepatitis b virale polypeptide Expired - Fee Related DE69814884T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9720033.1A GB9720033D0 (en) 1997-09-19 1997-09-19 Hepatitis B virus polypeptides
GB9720033 1997-09-19
PCT/GB1998/002852 WO1999015671A1 (en) 1997-09-19 1998-09-21 Hepatitis b virus polypeptides

Publications (2)

Publication Number Publication Date
DE69814884D1 true DE69814884D1 (de) 2003-06-26
DE69814884T2 DE69814884T2 (de) 2004-03-11

Family

ID=10819394

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69814884T Expired - Fee Related DE69814884T2 (de) 1997-09-19 1998-09-21 Hepatitis b virale polypeptide

Country Status (15)

Country Link
US (1) US20040258709A1 (de)
EP (1) EP1015593B1 (de)
JP (1) JP2001517447A (de)
KR (1) KR100637282B1 (de)
AT (1) ATE241013T1 (de)
AU (1) AU751646B2 (de)
CA (1) CA2304255C (de)
CZ (1) CZ297131B6 (de)
DE (1) DE69814884T2 (de)
ES (1) ES2199460T3 (de)
GB (1) GB9720033D0 (de)
HU (1) HUP0003511A3 (de)
NO (1) NO20001397L (de)
PL (1) PL195242B1 (de)
WO (1) WO1999015671A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0009470D0 (en) 2000-04-17 2000-06-07 Univ Southampton Materials and methods relating to immune responses to fusion proteins
EP1281761A1 (de) * 2001-07-27 2003-02-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Synthetische Polypeptide die vom pre-S1 Protein des Hepatitis B Virus ableitbar sind und deren Verwendung
DE602004017864D1 (de) * 2003-06-23 2009-01-02 Baxter Int Trägerproteine für impfstoffe
CN100537762C (zh) * 2004-06-24 2009-09-09 中国人民解放军军事医学科学院野战输血研究所 一种嵌合型病毒样颗粒疫苗载体蛋白及其制备方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0299242A3 (de) * 1987-06-22 1989-01-25 Medico Labs Ag Heterologe, virale, immunogen wirksame Peptidpartikel
EP0389983A3 (de) * 1989-03-31 1991-01-16 Abbott Laboratories Monoklonale Antikörper gegen PreS2- und PreS1-Polypeptide des Umhüllungsproteins des Hepatite B-Virus
WO1994001132A1 (en) * 1992-07-07 1994-01-20 Merck & Co., Inc. VACCINE COMPRISING MIXED preS1+preS2+S AND CORE PARTICLE
CA2141427C (en) * 1992-07-31 2008-07-22 Mohammed Anjam Khan Expression of recombinant fusion proteins in attenuated bacteria
DE69430246T2 (de) * 1993-07-30 2002-12-12 Medeva Holdings Bv Rekombinante tetc-fusionsprotein enthaltene impfstoffzusammensetzungen
GB9401795D0 (en) * 1994-01-31 1994-03-23 Medeva Holdings Bv Vaccines

Also Published As

Publication number Publication date
CA2304255C (en) 2009-07-07
CZ297131B6 (cs) 2006-09-13
HUP0003511A3 (en) 2003-08-28
US20040258709A1 (en) 2004-12-23
ES2199460T3 (es) 2004-02-16
AU751646B2 (en) 2002-08-22
HUP0003511A2 (hu) 2001-02-28
KR100637282B1 (ko) 2006-10-24
EP1015593B1 (de) 2003-05-21
WO1999015671A1 (en) 1999-04-01
GB9720033D0 (en) 1997-11-19
EP1015593A1 (de) 2000-07-05
CZ2000978A3 (cs) 2001-01-17
KR20010024176A (ko) 2001-03-26
NO20001397D0 (no) 2000-03-17
NO20001397L (no) 2000-05-05
ATE241013T1 (de) 2003-06-15
DE69814884T2 (de) 2004-03-11
PL195242B1 (pl) 2007-08-31
CA2304255A1 (en) 1999-04-01
JP2001517447A (ja) 2001-10-09
AU9174498A (en) 1999-04-12
PL339366A1 (en) 2000-12-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee