DE69807073D1 - Herstellung von tri-iodo-benzol-verbindungen - Google Patents

Herstellung von tri-iodo-benzol-verbindungen

Info

Publication number
DE69807073D1
DE69807073D1 DE69807073T DE69807073T DE69807073D1 DE 69807073 D1 DE69807073 D1 DE 69807073D1 DE 69807073 T DE69807073 T DE 69807073T DE 69807073 T DE69807073 T DE 69807073T DE 69807073 D1 DE69807073 D1 DE 69807073D1
Authority
DE
Germany
Prior art keywords
agent
added
temperature
range
benzol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69807073T
Other languages
English (en)
Other versions
DE69807073T2 (de
Inventor
Dick Malthe-Soerenssen
Magne Homestad
Britt Sterud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
Nycomed Imaging AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging AS filed Critical Nycomed Imaging AS
Publication of DE69807073D1 publication Critical patent/DE69807073D1/de
Application granted granted Critical
Publication of DE69807073T2 publication Critical patent/DE69807073T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Glass Compositions (AREA)
DE69807073T 1997-05-23 1998-05-22 Herstellung von tri-iodo-benzol-verbindungen Expired - Lifetime DE69807073T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9710725.4A GB9710725D0 (en) 1997-05-23 1997-05-23 Process
PCT/GB1998/001488 WO1998052908A1 (en) 1997-05-23 1998-05-22 Preparation of tri-iodo benzene compounds

Publications (2)

Publication Number Publication Date
DE69807073D1 true DE69807073D1 (de) 2002-09-12
DE69807073T2 DE69807073T2 (de) 2003-10-09

Family

ID=10812987

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69807073T Expired - Lifetime DE69807073T2 (de) 1997-05-23 1998-05-22 Herstellung von tri-iodo-benzol-verbindungen

Country Status (17)

Country Link
US (1) US6274762B1 (de)
EP (1) EP0984922B1 (de)
JP (1) JP4039700B2 (de)
KR (1) KR100544932B1 (de)
CN (1) CN1152854C (de)
AT (1) ATE221872T1 (de)
AU (1) AU7540498A (de)
BR (1) BR9809658A (de)
CA (1) CA2290529A1 (de)
CZ (1) CZ296389B6 (de)
DE (1) DE69807073T2 (de)
ES (1) ES2183366T3 (de)
GB (1) GB9710725D0 (de)
IL (1) IL133099A0 (de)
NO (1) NO327489B1 (de)
PT (1) PT984922E (de)
WO (1) WO1998052908A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100355710C (zh) * 2005-12-15 2007-12-19 上海交通大学 芳烃碘代物的制备方法
EP2243767A1 (de) * 2009-04-21 2010-10-27 Bracco Imaging S.p.A Verfahren zur Iodierung aromatischer Verbindungen
US7863484B1 (en) 2009-07-21 2011-01-04 Ge Healthcare As Method for reducing aminoisophthalic acid bisamide related impurities in preparation of non-ionic X-ray contrast agents
EP2277846A1 (de) 2009-07-21 2011-01-26 GE Healthcare AS Erhalt freien Iods bei der Herstellung von wässrigem Iodchlorid durch Zugabe von Iodid
US20110021834A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Continuous process of preparing intermediate for non-ionic x-ray contrast agents
US20110021833A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Crystallization of an intermediate for synthesizing non-ionic x-ray contrast agents
US20110020238A1 (en) 2009-07-21 2011-01-27 Ge Healthcare As Stabilizing aqueous solution of iodine chloride by adding sodium chloride
JP5754842B2 (ja) * 2011-03-02 2015-07-29 株式会社 東邦アーステック ｐ−ヨードフェノールの製造方法
CN103086915A (zh) * 2011-10-31 2013-05-08 上海海神化学生物科技有限公司 制备3,5-二取代-2,4,6-三碘代芳香胺类化合物的碘化方法
KR101887516B1 (ko) 2011-10-31 2018-08-10 아이맥스 다이어그노스틱 이미징 홀딩 리미티드 3,5-디치환된-2,4,6-트리요오도 아로마틱 아민 화합물의 제조를 위한 요오드화 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3145197A (en) * 1961-06-26 1964-08-18 Mallinckrodt Chemical Works 5-acetamido-nu-alkyl-2, 4, 6-trhodoiso-phthalamic acid compounds
SE348727B (de) * 1969-07-08 1972-09-11 Pharmacia Ab
GB1466852A (en) * 1973-05-18 1977-03-09 Nyegaard & Co As Iodination process
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
US4125599A (en) * 1976-08-19 1978-11-14 Mallinckrodt, Inc. X-ray contrast agents
FR2614299B1 (fr) * 1987-04-23 1989-08-18 Guerbet Sa Composes diamino benzeniques iodes, leur procede de preparation et produits de contraste les contenant.
US5013865A (en) * 1988-04-06 1991-05-07 Mallinckrodt, Inc. Process for the preparation of 2,4,6-triiodo-5-amino-N-alkylisophthalamic acid and 2,4,6-triiodo-5-amino-isophthalamide compounds
AU623403B2 (en) * 1988-04-06 1992-05-14 Mallinckrodt, Inc. Process for the preparation of 2,4,6-triiodo-5-amino-n-alkylisophthalamic acid

Also Published As

Publication number Publication date
NO327489B1 (no) 2009-07-13
NO995675L (no) 1999-11-19
ES2183366T3 (es) 2003-03-16
KR20010012824A (ko) 2001-02-26
WO1998052908A1 (en) 1998-11-26
CN1152854C (zh) 2004-06-09
KR100544932B1 (ko) 2006-01-24
BR9809658A (pt) 2000-07-11
EP0984922B1 (de) 2002-08-07
CN1257476A (zh) 2000-06-21
JP4039700B2 (ja) 2008-01-30
CZ417299A3 (cs) 2000-05-17
EP0984922A1 (de) 2000-03-15
US6274762B1 (en) 2001-08-14
IL133099A0 (en) 2001-03-19
ATE221872T1 (de) 2002-08-15
JP2001526677A (ja) 2001-12-18
AU7540498A (en) 1998-12-11
NO995675D0 (no) 1999-11-19
GB9710725D0 (en) 1997-07-16
PT984922E (pt) 2002-12-31
CA2290529A1 (en) 1998-11-26
CZ296389B6 (cs) 2006-03-15
DE69807073T2 (de) 2003-10-09

Similar Documents

Publication Publication Date Title
EE03869B1 (et) Sulfiinhappe derivaadid, nende valmistamine ja kasutamine
EA199800579A1 (ru) Новые производные 5-амино-3-циано-4-этилсульфинил-1-фенилпиразола и их применение в качестве пестицидов
TR200100238T2 (tr) Yeni sübstitüe edilmiş pirazol türevleri
BR0009411A (pt) Composto de anilina substituìda, e, processo para a preparação e uso de compostos
DE3581566D1 (de) Oxindol-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte.
BR9809111A (pt) Novos intermediários e processo para sua preparação
DE69807073D1 (de) Herstellung von tri-iodo-benzol-verbindungen
ES2001703A6 (es) Procedimiento para la preparracion de derrrivados de acidos 2-(2-imidazolin -2-il)- piridin -3- carboxilicos.
ATE1625T1 (de) Isoxazolylcarbonsaeureanilide, ihre herstellung, diese enthaltende fungizide mittel und verfahren zur bekaempfung von pilzen.
ATE226585T1 (de) Thiazolobenzoheterocyclen, ihre herstellung und diese enthaltende phatrmazeutische zubereitungen
ID27440A (id) Proses untuk menyiapkan penengah-penengah
TR200001122T2 (tr) Farmasötikler olarak bifenil türevleri.
ES480391A1 (es) Un procedimiento para la preparacion de derivados de difeni-lamina.
DK0725776T3 (da) 3-Aryl-4-alkyl- og 4,5-dialkyl-4H-1,2,4-triazoler anvendelige som hukommelsesforbedrende midler
ES482949A1 (es) Un procedimiento para la preparacion de compuestos derivadosde piridoxina
DK0994851T3 (da) Fremgangsmåde til fremstilling af 2-alkylthio-substiuerede benzoesyrederivater
DK428087A (da) Dihydropyridin-5-phosphonsyre-cyclopropylenester
SE8107470L (sv) Imidazolderivat
RS49787B (sr) Postupak za dobijanje hlorbenzoksazola
ES8103050A1 (es) Un procedimiento para la preparacion de un derivado de pira-zol
ATE177418T1 (de) Benzoylderivate und ihre herstellung
JPS57159729A (en) Manufacture of trichloromethyl-substituted aromatic compounds and aromatic compounds obtained thereby
IT1270834B (it) Disolfuro chinolico
ATE20749T1 (de) Dithiino (1,4) (2,3-c) pyrrolderivate, ihre herstellung und solche enthaltende arzneimittel.

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: AMERSHAM HEALTH AS, OSLO, NO

8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: GE HEALTHCARE AS, OSLO, NO

8328 Change in the person/name/address of the agent

Representative=s name: HAMMONDS LLP, LONDON, GB

R082 Change of representative

Ref document number: 984922

Country of ref document: EP

Representative=s name: J D REYNOLDS & CO., GB