DE69803041T2 - Thermo-zyklus-vorrichtung zur ausführung der polymerase-kettenreaktion - Google Patents

Thermo-zyklus-vorrichtung zur ausführung der polymerase-kettenreaktion

Info

Publication number
DE69803041T2
DE69803041T2 DE69803041T DE69803041T DE69803041T2 DE 69803041 T2 DE69803041 T2 DE 69803041T2 DE 69803041 T DE69803041 T DE 69803041T DE 69803041 T DE69803041 T DE 69803041T DE 69803041 T2 DE69803041 T2 DE 69803041T2
Authority
DE
Germany
Prior art keywords
chain reaction
polymerase chain
assembly
carrying
thermal cycle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69803041T
Other languages
English (en)
Other versions
DE69803041D1 (de
Inventor
G Atwood
Adrian Fawcett
S Ferrara
M Hetherington
W Noreiks
E Olsen
R Widomski
M Wittmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems LLC
Original Assignee
PE Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26718481&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69803041(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by PE Corp filed Critical PE Corp
Publication of DE69803041D1 publication Critical patent/DE69803041D1/de
Application granted granted Critical
Publication of DE69803041T2 publication Critical patent/DE69803041T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50853Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R27/00Arrangements for measuring resistance, reactance, impedance, or electric characteristics derived therefrom
    • G01R27/02Measuring real or complex resistance, reactance, impedance, or other two-pole characteristics derived therefrom, e.g. time constant
    • G01R27/20Measuring earth resistance; Measuring contact resistance, e.g. of earth connections, e.g. plates
    • G01R27/205Measuring contact resistance of connections, e.g. of earth connections
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05DSYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D23/00Control of temperature
    • G05D23/19Control of temperature characterised by the use of electric means
    • G05D23/1919Control of temperature characterised by the use of electric means characterised by the type of controller
    • HELECTRICITY
    • H10SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10NELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10N10/00Thermoelectric devices comprising a junction of dissimilar materials, i.e. devices exhibiting Seebeck or Peltier effects
    • H10N10/10Thermoelectric devices comprising a junction of dissimilar materials, i.e. devices exhibiting Seebeck or Peltier effects operating with only the Peltier or Seebeck effects
    • H10N10/13Thermoelectric devices comprising a junction of dissimilar materials, i.e. devices exhibiting Seebeck or Peltier effects operating with only the Peltier or Seebeck effects characterised by the heat-exchanging means at the junction
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/045Connecting closures to device or container whereby the whole cover is slidable
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
DE69803041T 1997-03-28 1998-03-30 Thermo-zyklus-vorrichtung zur ausführung der polymerase-kettenreaktion Expired - Lifetime DE69803041T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4175497P 1997-03-28 1997-03-28
US4612297P 1997-05-09 1997-05-09
PCT/US1998/006189 WO1998043740A2 (en) 1997-03-28 1998-03-30 Improvements in thermal cycler for pcr

Publications (2)

Publication Number Publication Date
DE69803041D1 DE69803041D1 (de) 2002-01-31
DE69803041T2 true DE69803041T2 (de) 2002-07-11

Family

ID=26718481

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69818869T Expired - Lifetime DE69818869T2 (de) 1997-03-28 1998-03-30 Einrichtung für Thermozyklier-Geräten für PCR
DE69803041T Expired - Lifetime DE69803041T2 (de) 1997-03-28 1998-03-30 Thermo-zyklus-vorrichtung zur ausführung der polymerase-kettenreaktion

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69818869T Expired - Lifetime DE69818869T2 (de) 1997-03-28 1998-03-30 Einrichtung für Thermozyklier-Geräten für PCR

Country Status (7)

Country Link
EP (5) EP0963250B1 (de)
JP (5) JP2001521379A (de)
AT (2) ATE251496T1 (de)
AU (1) AU736484B2 (de)
CA (1) CA2285377C (de)
DE (2) DE69818869T2 (de)
WO (1) WO1998043740A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102017205857B3 (de) 2017-04-06 2018-06-07 Audi Ag Kühleinrichtung, insbesondere für Elektronikbauteile, und Elektronikanordnung damit

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0007219D0 (en) * 2000-03-24 2000-05-17 Bjs Company Ltd Heating specimen carriers
US7133726B1 (en) 1997-03-28 2006-11-07 Applera Corporation Thermal cycler for PCR
CA2324281A1 (en) * 1998-03-23 1999-09-30 Cepheid Multi-site reactor system with dynamic, independent control of individual reaction sites
US6780617B2 (en) 2000-12-29 2004-08-24 Chen & Chen, Llc Sample processing device and method
JP4321738B2 (ja) 1998-06-24 2009-08-26 チェン アンド チェン エルエルシー 液体試料試験システム
EP1045038A1 (de) 1999-04-08 2000-10-18 Hans-Knöll-Institut Für Naturstoff-Forschung E.V. Thermisches Kreisprozessgerät mit Wärmeblock
US6657169B2 (en) * 1999-07-30 2003-12-02 Stratagene Apparatus for thermally cycling samples of biological material with substantial temperature uniformity
ATE237399T1 (de) 1999-09-29 2003-05-15 Tecan Trading Ag Thermocycler sowie hebeelement für mikrotiterplatte
DE29917313U1 (de) * 1999-10-01 2001-02-15 Mwg Biotech Ag Vorrichtung zur Durchführung chemischer oder biologischer Reaktionen
US6699713B2 (en) 2000-01-04 2004-03-02 The Regents Of The University Of California Polymerase chain reaction system
US7169355B1 (en) 2000-02-02 2007-01-30 Applera Corporation Apparatus and method for ejecting sample well trays
WO2002041999A1 (en) * 2000-11-24 2002-05-30 Novo Nordisk A/S Decondenser unit
KR20040008155A (ko) * 2001-04-09 2004-01-28 리써치 트라이앵글 인스티튜트 Dna 게놈 및 프로테옴 칩용, 열광학 스위칭 회로용,그리고 ir 태그용 박막 열전기 냉각 및 가열 장치
WO2003000419A2 (en) * 2001-06-21 2003-01-03 Hybaid Limited Sample well plate
EP1421455A1 (de) * 2001-06-27 2004-05-26 AB Implementa Hebe Einrichtung bei der durchführung eines prozesses in einem prozessmedium
CA2453253A1 (en) * 2001-07-13 2003-01-23 The University Of British Columbia Thermal cycling methods and apparatus
AU2002341644B2 (en) 2001-09-11 2008-02-28 Iquum, Inc. Sample vessels
EP1433208A4 (de) 2001-10-05 2008-02-20 Nextreme Thermal Solutions Inc Phononenblockierende, elektronendurchlassende niedrigdimensionale strukturen
CA2482363C (en) 2002-04-15 2011-06-14 Research Triangle Institute Thermoelectric device utilizing double-sided peltier junctions and method of making the device
US7452712B2 (en) * 2002-07-30 2008-11-18 Applied Biosystems Inc. Sample block apparatus and method of maintaining a microcard on a sample block
WO2005058501A1 (en) * 2002-09-09 2005-06-30 Bjs Company Ltd Heating samples in specimen carriers
US6730883B2 (en) 2002-10-02 2004-05-04 Stratagene Flexible heating cover assembly for thermal cycling of samples of biological material
US8676383B2 (en) * 2002-12-23 2014-03-18 Applied Biosystems, Llc Device for carrying out chemical or biological reactions
ES2604352T3 (es) 2003-02-05 2017-03-06 Iquum, Inc. Procesado de muestras
JP4705035B2 (ja) * 2003-05-23 2011-06-22 バイオ−ラッド ラボラトリーズ,インコーポレイティド 反応培地の空間配列に対し局部化した温度制御
US20050221358A1 (en) * 2003-09-19 2005-10-06 Carrillo Albert L Pressure chamber clamp mechanism
US20050226779A1 (en) 2003-09-19 2005-10-13 Oldham Mark F Vacuum assist for a microplate
US7659109B2 (en) 2004-05-17 2010-02-09 Applied Biosystems, Llc Pasting edge heater
EP1637228A1 (de) * 2004-09-16 2006-03-22 Roche Diagnostics GmbH Methode und Vorrichtung zum Ausführen schneller Thermocyclierung sowie mikrofluidisches System
US8063298B2 (en) 2004-10-22 2011-11-22 Nextreme Thermal Solutions, Inc. Methods of forming embedded thermoelectric coolers with adjacent thermally conductive fields
WO2007002342A2 (en) 2005-06-22 2007-01-04 Nextreme Thermal Solutions Methods of forming thermoelectric devices including electrically insulating matrixes between conductive traces and related structures
WO2007002337A2 (en) 2005-06-22 2007-01-04 Nextreme Thermal Solutions Methods of forming thermoelectric devices including conductive posts and/or different solder materials and related methods and structures
US7679203B2 (en) 2006-03-03 2010-03-16 Nextreme Thermal Solutions, Inc. Methods of forming thermoelectric devices using islands of thermoelectric material and related structures
US7958736B2 (en) * 2007-05-24 2011-06-14 Bio-Rad Laboratories, Inc. Thermoelectric device and heat sink assembly with reduced edge heat loss
EP2060324A1 (de) * 2007-11-13 2009-05-20 F.Hoffmann-La Roche Ag Wärmesperrvorrichtung
CA2716337C (en) 2008-02-20 2017-11-14 Streck, Inc. Thermocycler and sample vessel for rapid amplification of dna
JP5743891B2 (ja) 2008-09-23 2015-07-01 コーニンクレッカ フィリップス エヌ ヴェ サーモサイクルデバイス
CN101735949B (zh) * 2008-11-05 2012-10-10 广达电脑股份有限公司 变温装置
GB2511692A (en) * 2009-08-08 2014-09-10 Bibby Scient Ltd An apparatus for treating a test sample
GB2512764B (en) * 2009-08-08 2014-12-24 Bibby Scient Ltd An apparatus for treating a test sample
WO2011021640A1 (ja) * 2009-08-20 2011-02-24 タカラバイオ株式会社 温度サイクル装置
WO2011028834A2 (en) 2009-09-01 2011-03-10 Life Technologies Corporation Thermal block assemblies and instruments providing low thermal non-uniformity for rapid thermal cycling
EP2338594A1 (de) * 2009-12-23 2011-06-29 PEQLAB Biotechnologie GmbH Wärmeplatte
US9601677B2 (en) 2010-03-15 2017-03-21 Laird Durham, Inc. Thermoelectric (TE) devices/structures including thermoelectric elements with exposed major surfaces
SG184539A1 (en) 2010-04-09 2012-11-29 Life Technologies Corp Improved thermal uniformity for thermal cycler instrumentation using dynamic control
DE102010019231A1 (de) * 2010-05-03 2014-03-06 Eppendorf Ag Verbindung für einen temperierbaren Wechselblock
GB201009998D0 (en) * 2010-06-15 2010-07-21 Bg Res Cell disruption
EP2752671A3 (de) * 2010-07-23 2016-08-24 Beckman Coulter, Inc. System oder Verfahren zur Aufnahme analytischer Einheiten
WO2012075360A1 (en) * 2010-12-03 2012-06-07 Idaho Technology, Inc. Thermal cycler apparatus and related methods
EP2500957B1 (de) * 2011-03-17 2015-08-26 Braun GmbH Verfahren zum Testen eines Peltier-Elements sowie einer kleinen elektrischen Anwendung mit einem Peltier-Element und eine Sicherheitsvorrichtung
WO2012166913A1 (en) 2011-06-01 2012-12-06 Streck, Inc. Rapid thermocycler system for rapid amplification of nucleic acids and related methods
DE202011101712U1 (de) 2011-06-10 2012-09-13 Eppendorf Ag Labortemperierapparat mit Formkörpereinrichtung
WO2012176596A1 (ja) 2011-06-24 2012-12-27 株式会社日立ハイテクノロジーズ 核酸増幅装置及び核酸分析装置
CN103243017B (zh) * 2012-02-09 2015-04-29 卡尤迪生物科技(北京)有限公司 利用整体结构储热和散热的薄型pcr仪
JP5935980B2 (ja) * 2012-03-28 2016-06-15 セイコーエプソン株式会社 熱サイクル装置
JP5935981B2 (ja) * 2012-03-28 2016-06-15 セイコーエプソン株式会社 熱サイクル装置
BR112014032911A2 (pt) * 2012-06-28 2017-06-27 Fluoresentric Inc dispositivo indicador químico
CA2879638A1 (en) 2012-08-10 2014-02-13 Streck, Inc. Real-time optical system for polymerase chain reaction
JP2014143927A (ja) 2013-01-28 2014-08-14 Hitachi High-Technologies Corp 核酸増幅装置および温度調節機能の異常検出方法
EP2976156B1 (de) 2013-03-19 2021-04-07 Life Technologies Corporation Abdeckung für thermocycler
EP3495803A1 (de) 2013-06-28 2019-06-12 Streck, Inc. Vorrichtungen für echtzeit-polymerasekettenreaktionen
JP2015053893A (ja) * 2013-09-11 2015-03-23 公益財団法人神奈川科学技術アカデミー 高速遺伝子増幅検出装置
KR20160055248A (ko) 2013-09-16 2016-05-17 라이프 테크놀로지스 코포레이션 유전자증폭기에 열 균일성을 제공하기 위한 장치, 시스템 및 방법
CN103675454B (zh) * 2013-10-31 2015-12-30 成都金采科技有限公司 电阻测试装置
KR20160123356A (ko) 2014-02-18 2016-10-25 라이프 테크놀로지스 코포레이션 스케일러블 유전자증폭기를 제공하고 열전 장치를 격리시키기 위한 장치, 시스템 및 방법
DE112015005925B4 (de) 2015-02-23 2023-06-15 Hitachi High-Tech Corporation Nucleinsäure-Analysator
US10544966B2 (en) * 2015-07-23 2020-01-28 Cepheid Thermal control device and methods of use
JP6576750B2 (ja) * 2015-09-04 2019-09-18 Phcホールディングス株式会社 核酸増幅装置
GB2561446B (en) * 2015-09-09 2022-08-24 Hitachi High Tech Corp Temperature adjustment apparatus
US11583862B2 (en) 2015-09-15 2023-02-21 Life Technologies Corporation Systems and methods for biological analysis
CN108348915B (zh) * 2015-09-15 2022-11-08 生命技术公司 用于生物分析的系统和方法
TWI806116B (zh) 2015-10-01 2023-06-21 美商伯克利之光生命科技公司 多槽盤培養器、用於出入培養器之內部腔室之方法及培養系統
DE102015121362B4 (de) 2015-12-08 2018-05-24 Analytik Jena Ag Temperiervorrichtung mit einem Reaktionsgefäß
CN110366591A (zh) * 2016-12-01 2019-10-22 伯克利之光生命科技公司 井孔板培养器
IT201700089373A1 (it) 2017-08-03 2019-02-03 Petroceramics S P A Materiale composito fibro-rinforzato pre-impregnato e materiale composito ceramico fibro-rinforzato, ottenuto per formatura e successiva pirolisi di detto materiale pre-impregnato
IT201700089430A1 (it) 2017-08-03 2019-02-03 Petroceramics S P A Materiale composito fibro-rinforzato pre-impregnato e manufatto ottenuto per formatura e completo indurimento di detto materiale composito fibro-rinforzato pre-impregnato

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639883A (en) * 1984-11-28 1987-01-27 Rca Corporation Thermoelectric cooling system and method
US5038852A (en) * 1986-02-25 1991-08-13 Cetus Corporation Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
CA1339653C (en) * 1986-02-25 1998-02-03 Larry J. Johnson Appartus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
US5237821A (en) * 1987-08-20 1993-08-24 Kabushiki Kaisha Komatsu Seisakusho Multistep electronic cooler
EP0342155A3 (de) * 1988-05-13 1990-06-27 Agrogen-Stiftung Laboratoriumsgerät zum wahlweisen Heizen und Kühlen
US4881038A (en) * 1988-05-25 1989-11-14 Champlin Keith S Electric battery testing device with automatic voltage scaling to determine dynamic conductance
SE464595B (sv) * 1988-09-29 1991-05-13 Ffv Aerotech Ab Saett att med ett peltier-element med tvaa ytor bestaemma den ena eller baada ytornas temperatur
US4865986A (en) * 1988-10-06 1989-09-12 Coy Corporation Temperature control apparatus
DE4037955A1 (de) * 1989-12-05 1991-06-06 Bernd Seidl Vorrichtung zur aufnahme von probenbehaeltnissen
US5040381A (en) * 1990-04-19 1991-08-20 Prime Computer, Inc. Apparatus for cooling circuits
KR100236506B1 (ko) * 1990-11-29 2000-01-15 퍼킨-엘머시터스인스트루먼츠 폴리머라제 연쇄 반응 수행 장치
GB9123463D0 (en) * 1991-11-05 1991-12-18 Hybaid Ltd Reaction temperature control device
US5248934A (en) * 1992-01-10 1993-09-28 Roveti Denes K Method and apparatus for converting a conventional DC multimeter to an AC impedance meter
WO1994012833A1 (en) * 1992-11-27 1994-06-09 Pneumo Abex Corporation Thermoelectric device for heating and cooling air for human use
US5441576A (en) 1993-02-01 1995-08-15 Bierschenk; James L. Thermoelectric cooler
JP3113446B2 (ja) * 1993-03-26 2000-11-27 三洋電機株式会社 インキュベータ
CA2129787A1 (en) * 1993-08-27 1995-02-28 Russell G. Higuchi Monitoring multiple amplification reactions simultaneously and analyzing same
US5385022A (en) * 1993-09-09 1995-01-31 Kornblit; Levy Apparatus and method for deep thermoelectric refrigeration
CA2130013C (en) * 1993-09-10 1999-03-30 Rolf Moser Apparatus for automatic performance of temperature cycles
CA2130517C (en) * 1993-09-10 1999-10-05 Walter Fassbind Array of reaction containers for an apparatus for automatic performance of temperature cycles
US5511415A (en) 1994-01-18 1996-04-30 Cambridge Aeroflow, Inc. Gas flow and temperature probe and gas flow and temperature monitor system including one or more such probes
GB9406537D0 (en) * 1994-03-31 1994-05-25 British Aerospace Blind stitching apparatus and composite material manufacturing methods
WO1995027196A1 (en) * 1994-04-04 1995-10-12 Sanadi Ashok R Method and apparatus for preventing cross-contamination of multi-well test plates
US5410130A (en) * 1994-04-20 1995-04-25 Ericomp, Inc. Heating and temperature cycling
US5972716A (en) * 1994-04-29 1999-10-26 The Perkin-Elmer Corporation Fluorescence monitoring device with textured optical tube and method for reducing background fluorescence
US5600575A (en) * 1994-10-05 1997-02-04 Anticole; Robert B. Drive protection monitor for motor and amplifier
US5856174A (en) * 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102017205857B3 (de) 2017-04-06 2018-06-07 Audi Ag Kühleinrichtung, insbesondere für Elektronikbauteile, und Elektronikanordnung damit

Also Published As

Publication number Publication date
WO1998043740A3 (en) 1998-12-17
JP5058908B2 (ja) 2012-10-24
AU6786198A (en) 1998-10-22
ATE251496T1 (de) 2003-10-15
EP2156892B1 (de) 2013-05-08
CA2285377C (en) 2004-08-17
AU736484B2 (en) 2001-07-26
EP2186568A1 (de) 2010-05-19
EP2156892A2 (de) 2010-02-24
DE69803041D1 (de) 2002-01-31
JP2010104382A (ja) 2010-05-13
EP2913109A1 (de) 2015-09-02
EP0963250A2 (de) 1999-12-15
ATE211025T1 (de) 2002-01-15
CA2285377A1 (en) 1998-10-08
DE69818869T2 (de) 2004-09-09
JP5780707B2 (ja) 2015-09-16
JP2001521379A (ja) 2001-11-06
JP2012187124A (ja) 2012-10-04
EP2090366A3 (de) 2009-11-18
JP2015097526A (ja) 2015-05-28
EP2156892A3 (de) 2010-03-03
EP2090366B1 (de) 2012-12-19
JP2008278896A (ja) 2008-11-20
EP0963250B1 (de) 2001-12-19
EP2186568B1 (de) 2014-12-17
JP5996613B2 (ja) 2016-09-21
DE69818869D1 (de) 2003-11-13
EP2090366A2 (de) 2009-08-19
WO1998043740A2 (en) 1998-10-08

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