DE69739480D1 - Menschliche hämatopoietische stamm und vorläuferzellantigen und methoden zu dessen verwendung - Google Patents

Menschliche hämatopoietische stamm und vorläuferzellantigen und methoden zu dessen verwendung

Info

Publication number
DE69739480D1
DE69739480D1 DE69739480T DE69739480T DE69739480D1 DE 69739480 D1 DE69739480 D1 DE 69739480D1 DE 69739480 T DE69739480 T DE 69739480T DE 69739480 T DE69739480 T DE 69739480T DE 69739480 D1 DE69739480 D1 DE 69739480D1
Authority
DE
Germany
Prior art keywords
antigen
cell
hematopoietic
subset
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69739480T
Other languages
English (en)
Inventor
Sheri Miraglia
Wayne G Godfry
Amy Yin
David Buck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Miltenyi Biotec GmbH
Original Assignee
Miltenyi Biotec GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/639,891 external-priority patent/US5843633A/en
Application filed by Miltenyi Biotec GmbH filed Critical Miltenyi Biotec GmbH
Application granted granted Critical
Publication of DE69739480D1 publication Critical patent/DE69739480D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806Antigenic peptides or proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/838Marrow; spleen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69739480T 1996-04-26 1997-04-25 Menschliche hämatopoietische stamm und vorläuferzellantigen und methoden zu dessen verwendung Expired - Lifetime DE69739480D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/639,891 US5843633A (en) 1996-04-26 1996-04-26 Characterization of a human hematopoietic progenitor cell antigen
US08/842,382 US6455678B1 (en) 1996-04-26 1997-04-23 Human hematopoietic stem and progenitor cell antigen
PCT/US1997/006930 WO1997041224A1 (en) 1996-04-26 1997-04-25 Human hematopoietic stem and progenitor cell antigen and methods for its use

Publications (1)

Publication Number Publication Date
DE69739480D1 true DE69739480D1 (de) 2009-08-13

Family

ID=27093419

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69739480T Expired - Lifetime DE69739480D1 (de) 1996-04-26 1997-04-25 Menschliche hämatopoietische stamm und vorläuferzellantigen und methoden zu dessen verwendung

Country Status (10)

Country Link
US (4) US6455678B1 (de)
EP (1) EP0953046B1 (de)
JP (3) JP3908279B2 (de)
AT (1) ATE435282T1 (de)
AU (1) AU720938B2 (de)
CA (1) CA2251604C (de)
DE (1) DE69739480D1 (de)
DK (1) DK0953046T3 (de)
ES (1) ES2327691T3 (de)
WO (1) WO1997041224A1 (de)

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US6310195B1 (en) 1997-06-24 2001-10-30 Imclone Systems Incorporated Nucleic acid encoding a lectin-derived progenitor cell preservation factor
US7361336B1 (en) * 1997-09-18 2008-04-22 Ivan Bergstein Methods of cancer therapy targeted against a cancer stem line
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AU784361C (en) * 1999-12-30 2007-03-15 Imclone Systems Incorporated Progenitor cell preservation factors and related methods and products
US6566502B1 (en) 2000-01-28 2003-05-20 Eos Biotechnology, Inc. Methods of diagnosing cancer, compositions, and methods of screening for cancer modulators
US6455668B1 (en) 2000-01-28 2002-09-24 Eos Biotechnology, Inc. Methods of diagnosing colorectal cancer, compositions, and methods of screening for colorectal cancer modulators
US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US20030229393A1 (en) * 2001-03-15 2003-12-11 Kutryk Michael J. B. Medical device with coating that promotes cell adherence and differentiation
US8460367B2 (en) * 2000-03-15 2013-06-11 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US20070055367A1 (en) * 2000-03-15 2007-03-08 Orbus Medical Technologies, Inc. Medical device with coating that promotes endothelial cell adherence and differentiation
US7037332B2 (en) 2000-03-15 2006-05-02 Orbus Medical Technologies, Inc. Medical device with coating that promotes endothelial cell adherence
US6682890B2 (en) 2000-08-17 2004-01-27 Protein Design Labs, Inc. Methods of diagnosing and determining prognosis of colorectal cancer
JP4198990B2 (ja) * 2000-10-18 2008-12-17 ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド 造血細胞のe−セレクチン/l−セレクチンリガンドポリペプチドおよびその使用法
CA2678490A1 (en) 2000-12-06 2002-06-13 Robert J. Hariri Isolated placental perfusate and placental cells isolated therefrom
ATE438708T1 (de) * 2001-11-15 2009-08-15 Childrens Medical Center Verfahren zur isolierung, expansion und differenzierung fötaler stammzellen aus chorionzotte, fruchtwasser und plazenta und therapeutische verwendungen davon
WO2003066097A2 (en) * 2002-02-08 2003-08-14 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw A novel target to inhibit angiogenesis
AU2003278741B2 (en) 2002-08-27 2008-02-14 Stemcells California Inc. Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations
US7252976B2 (en) * 2002-08-28 2007-08-07 Board Of Regents The University Of Texas System Quantitative RT-PCR to AC133 to diagnose cancer and monitor angiogenic activity in a cell sample
US7470538B2 (en) * 2002-12-05 2008-12-30 Case Western Reserve University Cell-based therapies for ischemia
US20040258670A1 (en) * 2002-12-05 2004-12-23 Case Western Reserve University Cell-based therapies for ischemia
US20070212732A1 (en) * 2003-08-27 2007-09-13 Nobuko Uchida Enriched Pancreatic Stem Cell and Progenitor Cell Populations, and Methods for Identifying, Isolating and Enriching for Such Populations
EP1740219B1 (de) * 2004-04-30 2015-03-04 OrbusNeich Medical, Inc. Medizinprodukt mit beschichtung zur erfassung von genetisch veränderten zellen und anwendungsverfahren dafür
US8026054B2 (en) * 2004-06-14 2011-09-27 The Board Of Trustees Of The University Of Illinois Antibodies against cells of fetal origin
WO2006081249A2 (en) 2005-01-25 2006-08-03 Cell Therapeutics, Inc. Conjugates of biologically active proteins having a modified in vivo half-life
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
ES2708933T3 (es) 2005-12-29 2019-04-12 Celularity Inc Poblaciones de células madre placentarias
TW200813086A (en) * 2006-05-11 2008-03-16 Hoffmann La Roche Immunereconstituted mouse
CA2700573C (en) 2006-09-26 2016-11-22 Cedars-Sinai Medical Center Cancer stem cell antigen vaccines and methods
US8097256B2 (en) 2006-09-28 2012-01-17 Cedars-Sinai Medical Center Cancer vaccines and vaccination methods
WO2008085229A2 (en) * 2006-11-15 2008-07-17 Arteriocyte Inc. Cell-based therapies for treating liver disease
AU2009276704B2 (en) 2008-07-28 2015-01-22 Children's Medical Center Corporation Prominin-1 peptide fragments and uses thereof
PL2328923T3 (pl) 2008-09-02 2016-06-30 Cedars Sinai Medical Center Epitopy CD133
GB0823553D0 (en) * 2008-12-24 2009-01-28 Immunosolv Ltd Cell separation technique
PT2427485T (pt) * 2009-05-07 2017-03-13 Immunocellular Therapeutics Ltd Epitopos cd133
EP2528938A4 (de) 2010-01-27 2013-10-23 Childrens Medical Center Proangiogene fragmente von prominin-1 und verwendungen davon
CA2800488A1 (en) 2010-05-26 2011-12-01 Regents Of The University Of Minnesota Single-chain variable fragment anti-cd133 antibodies and uses thereof
US8895291B2 (en) 2010-10-08 2014-11-25 Terumo Bct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
AR093183A1 (es) 2010-12-31 2015-05-27 Anthrogenesis Corp Aumento de la potencia de celulas madre de placenta usando moleculas de arn moduladoras
US9574179B2 (en) 2011-02-08 2017-02-21 Cellular Dynamics International, Inc. Hematopoietic precursor cell production by programming
TWI602570B (zh) 2011-06-01 2017-10-21 安瑟吉納西斯公司 使用胎盤幹細胞之疼痛治療
WO2013055476A1 (en) 2011-09-09 2013-04-18 Anthrogenesis Corporation Treatment of amyotrophic lateral sclerosis using placental stem cells
US10047345B2 (en) 2012-02-13 2018-08-14 Gamida-Cell Ltd. Culturing of mesenchymal stem cells with FGF4 and nicotinamide
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
ES2914373T3 (es) 2012-08-29 2022-06-10 Inguran Llc Eliminación magnética o identificación de células o de estructuras celulares dañadas o comprometidas
US10379026B2 (en) 2012-08-29 2019-08-13 Inguran, Llc Cell processing using magnetic particles
US10137182B2 (en) 2013-02-14 2018-11-27 Immunocellular Therapeutics, Ltd. Cancer vaccines and vaccination methods
CN105992816B (zh) 2013-11-16 2018-04-17 泰尔茂比司特公司 生物反应器中的细胞扩增
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JP6830059B2 (ja) 2014-09-26 2021-02-17 テルモ ビーシーティー、インコーポレーテッド スケジュール化された細胞フィーディング
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CN111560053B (zh) * 2020-06-17 2022-05-27 清华大学深圳国际研究生院 一种cd133拮抗多肽及其衍生物与应用
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Also Published As

Publication number Publication date
EP0953046A1 (de) 1999-11-03
CA2251604C (en) 2012-05-29
DK0953046T3 (da) 2009-08-10
JP3908279B2 (ja) 2007-04-25
ATE435282T1 (de) 2009-07-15
JP2006246898A (ja) 2006-09-21
US20050214861A1 (en) 2005-09-29
AU2682197A (en) 1997-11-19
US20090093052A1 (en) 2009-04-09
CA2251604A1 (en) 1997-11-06
US6455678B1 (en) 2002-09-24
EP0953046B1 (de) 2009-07-01
WO1997041224A1 (en) 1997-11-06
US20010051372A1 (en) 2001-12-13
JP2000509277A (ja) 2000-07-25
US8084033B2 (en) 2011-12-27
JP2006149396A (ja) 2006-06-15
ES2327691T3 (es) 2009-11-02
AU720938B2 (en) 2000-06-15

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