DE69738667D1 - Vorbeugung und behandlung von kolonadenom oder kolonmikroadenom mit 6-fluorursodeoxycholsäure - Google Patents

Vorbeugung und behandlung von kolonadenom oder kolonmikroadenom mit 6-fluorursodeoxycholsäure

Info

Publication number
DE69738667D1
DE69738667D1 DE69738667T DE69738667T DE69738667D1 DE 69738667 D1 DE69738667 D1 DE 69738667D1 DE 69738667 T DE69738667 T DE 69738667T DE 69738667 T DE69738667 T DE 69738667T DE 69738667 D1 DE69738667 D1 DE 69738667D1
Authority
DE
Germany
Prior art keywords
treatment
colonmicroadenoma
colonadomeno
preventation
fluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69738667T
Other languages
German (de)
English (en)
Inventor
Joyce Corey Gibson
Leonhard Robert Capuano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of DE69738667D1 publication Critical patent/DE69738667D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DE69738667T 1996-05-23 1997-05-22 Vorbeugung und behandlung von kolonadenom oder kolonmikroadenom mit 6-fluorursodeoxycholsäure Expired - Lifetime DE69738667D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1820296P 1996-05-23 1996-05-23
PCT/EP1997/002632 WO1997044043A1 (en) 1996-05-23 1997-05-22 Prevention and treatment of colorectal cancer by 6-fluoroursodeoxycholic acid (6-fudca)

Publications (1)

Publication Number Publication Date
DE69738667D1 true DE69738667D1 (de) 2008-06-19

Family

ID=21786767

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69738667T Expired - Lifetime DE69738667D1 (de) 1996-05-23 1997-05-22 Vorbeugung und behandlung von kolonadenom oder kolonmikroadenom mit 6-fluorursodeoxycholsäure

Country Status (10)

Country Link
US (1) US6426340B1 (https=)
EP (1) EP0906106B1 (https=)
JP (2) JP2000510858A (https=)
AT (1) ATE394107T1 (https=)
AU (1) AU3091597A (https=)
CA (1) CA2253593C (https=)
DE (1) DE69738667D1 (https=)
ES (1) ES2306459T3 (https=)
PT (1) PT906106E (https=)
WO (1) WO1997044043A1 (https=)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU758679B2 (en) * 1998-07-24 2003-03-27 Seo Hong Yoo Preparation of aqueous clear solution dosage forms with bile acids
EP1105141B1 (de) * 1998-08-06 2003-11-05 Wolfgang Stremmel Phosphatidylcholin als arzneimittel mit schleimhautschützender wirkung
RS50303B (sr) * 1999-09-28 2009-09-08 Panacea Biotec Limited, Farmaceutska kompozicija nimesulida sa kontrolisanim oslobađanjem
US7053076B2 (en) 2001-08-29 2006-05-30 Xenoport, Inc. Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs
AU2003287300A1 (en) * 2002-11-01 2004-06-07 James Kaput Identification of diet-regulated disease-associated genes
WO2008088836A2 (en) * 2007-01-16 2008-07-24 The Burnham Institute For Medical Research Compositions and methods for treatment of colorectal cancer
EP2255813A1 (en) * 2009-05-29 2010-12-01 The Royal College of Surgeons in Ireland Derivatives of ursodeoxycholic acid for the treatment of diarrhoea
PL3400944T3 (pl) 2010-11-04 2020-11-16 Albireo Ab Inhibitory ibat w leczeniu chorób wątroby
CA2952406A1 (en) 2014-06-25 2015-12-30 Ea Pharma Co., Ltd. Solid formulation and method for preventing or reducing coloration thereof
US10441604B2 (en) 2016-02-09 2019-10-15 Albireo Ab Cholestyramine pellets and methods for preparation thereof
US10441605B2 (en) 2016-02-09 2019-10-15 Albireo Ab Oral cholestyramine formulation and use thereof
US10786529B2 (en) 2016-02-09 2020-09-29 Albireo Ab Oral cholestyramine formulation and use thereof
JP2020530448A (ja) 2017-08-09 2020-10-22 アルビレオ・アクチボラグ コレスチラミン顆粒、経口コレスチラミン製剤、及びそれらの使用
US10793534B2 (en) 2018-06-05 2020-10-06 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
ES2942443T3 (es) 2018-06-05 2023-06-01 Albireo Ab Compuestos de benzotia(di)azepina y su uso como moduladores de ácidos biliares
US11801226B2 (en) 2018-06-20 2023-10-31 Albireo Ab Pharmaceutical formulation of odevixibat
BR112020024479A2 (pt) 2018-06-20 2021-03-02 Albireo Ab hidrato cristalino, modificações cristalinas de odevixibat, solvato misto de odevixibat, uso de modificação cristalina de odevixibat, processo para a preparação de modificação cristalina de odevixibat, e, composição farmacêutica
GB201812382D0 (en) 2018-07-30 2018-09-12 Nzp Uk Ltd Compounds
US10722457B2 (en) 2018-08-09 2020-07-28 Albireo Ab Oral cholestyramine formulation and use thereof
US11549878B2 (en) 2018-08-09 2023-01-10 Albireo Ab In vitro method for determining the adsorbing capacity of an insoluble adsorbant
US11007142B2 (en) 2018-08-09 2021-05-18 Albireo Ab Oral cholestyramine formulation and use thereof
US10941127B2 (en) 2019-02-06 2021-03-09 Albireo Ab Benzothiadiazepine compounds and their use as bile acid modulators
HUE060905T2 (hu) 2019-02-06 2023-04-28 Albireo Ab Benzotiadiazepin vegyületek és azok alkalmazása epesav modulátorként
US10975045B2 (en) 2019-02-06 2021-04-13 Aibireo AB Benzothiazepine compounds and their use as bile acid modulators
US11014898B1 (en) 2020-12-04 2021-05-25 Albireo Ab Benzothiazepine compounds and their use as bile acid modulators
ES2973549T3 (es) 2019-12-04 2024-06-20 Albireo Ab Compuestos de benzoti(di)azepina y su uso como moduladores de los ácidos biliares
CN114786772B (zh) 2019-12-04 2024-04-09 阿尔比里奥公司 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途
CA3158181A1 (en) 2019-12-04 2021-06-10 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
CA3158184A1 (en) 2019-12-04 2021-08-10 Albireo Ab Benzothiadiazepine compounds and their use as bile acid modulators
EP4188541B1 (en) 2020-08-03 2024-12-25 Albireo AB Benzothia(di)azepine compounds and their use as bile acid modulators
JP2023549226A (ja) 2020-11-12 2023-11-22 アルビレオ エービー 進行性家族性肝内胆汁うっ滞症（ｐｆｉｃ）を処置するためのオデビキシバット
JP2024500309A (ja) 2020-12-04 2024-01-09 アルビレオ エービー ベンゾチア（ジ）アゼピン化合物および胆汁酸モジュレータとしてのその使用
TW202313579A (zh) 2021-06-03 2023-04-01 瑞典商艾爾比瑞歐公司 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8825526D0 (en) * 1988-11-01 1988-12-07 Enzymatix Ltd Diagnosis
US5175320A (en) * 1989-04-17 1992-12-29 Giuliani S.P.A. Fluorinated bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
US5843929A (en) 1996-03-22 1998-12-01 Mayo Foundation For Medical Education And Research Chemoprevention of metachronous adenomatous colorectal polyps

Also Published As

Publication number Publication date
EP0906106A1 (en) 1999-04-07
JP2010059175A (ja) 2010-03-18
AU3091597A (en) 1997-12-09
CA2253593A1 (en) 1997-11-27
JP2000510858A (ja) 2000-08-22
ATE394107T1 (de) 2008-05-15
PT906106E (pt) 2008-08-07
ES2306459T3 (es) 2008-11-01
WO1997044043A1 (en) 1997-11-27
US6426340B1 (en) 2002-07-30
EP0906106B1 (en) 2008-05-07
CA2253593C (en) 2008-07-08

Similar Documents

Publication Publication Date Title
DE69738667D1 (de) Vorbeugung und behandlung von kolonadenom oder kolonmikroadenom mit 6-fluorursodeoxycholsäure
BG102668A (en) Application of ppar-alpha and prar-gamma antagonist for the treatment of syndrome x
IS1907B (is) Notkun klóbindiefnisins klíókínól við að framleiða lyfjablöndu til að meðhöndla Alzheimers-sjúkdóm
ATE170077T1 (de) Verfahren zur behandlung von krebs durch kombinationstherapie mit 2'- halomethylidenderivaten und einem s- oder m-phase spezifischen antineoplastischen wirkstoff
AU2740797A (en) Androstene derivatives
MY119375A (en) Treatment of tinnitus using neuroprotective agents
MY106528A (en) Method of treating impotence.
IL113566A0 (en) Use of certain methanebisphosphonic acid derivatives to prevent prosthesis loosening and prosthesis migration
WO2001030802A3 (en) Therapeutic treatments comprising administration of certain steroids for blood cell deficiencies
MY121623A (en) Methods of preventing breast cancer.
MY118986A (en) Use of (alpha)-1-adrenoreceptor antagonists in the prevention and treatment of benign prostatic hyperplasia
TR199701520T1 (xx) Ac�n�n iyile�tirilmesi i�in analjesik bile�ikleri �reten h�cre soyu.
CA2156481A1 (en) 5-ht2 receptor antagonist compositions useful in treating venous conditions
DK1124566T3 (da) Ikke-fermenteret osmotisk laxativ til behandling og forebyggelse af colorectale cancere
MY126321A (en) Use of (alpha)-adrenoreceptor antagonists in the prevention and treatment of cancer.
IS4847A (is) Aðferð til meðferðar gegn hjartabilun þar sem notuð eru mótlyf gegn endóþelíni
RU96102110A (ru) Способ профилактики и лечения изъязвлений роговицы
AU4937499A (en) Use of succinic acid or salts thereof and method of treating insulin resistance
AU6846300A (en) Use of cyamemazine for cold turkey benzodiazepine treatment
AU4042795A (en) Treatment of non-small cell lung carcinoma
NO984196L (no) FremgangsmÕte for behandling av stoffmisbruk
MX9604692A (es) Derivados de quinoxalina para el tratamiento de tinnitus.
AU5434899A (en) Cancer treatment
DE60039122D1 (de) 6-o-alkyl-2-nor-2-substituierte ketolidderivate
DK1019066T3 (da) Fremgangsmåder og præparater til forebyggelse og behandling af halsbrand

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN