DE69738416D1 - Liposomale zubereitungen von indolocarbazol-derivaten - Google Patents

Liposomale zubereitungen von indolocarbazol-derivaten

Info

Publication number
DE69738416D1
DE69738416D1 DE69738416T DE69738416T DE69738416D1 DE 69738416 D1 DE69738416 D1 DE 69738416D1 DE 69738416 T DE69738416 T DE 69738416T DE 69738416 T DE69738416 T DE 69738416T DE 69738416 D1 DE69738416 D1 DE 69738416D1
Authority
DE
Germany
Prior art keywords
indolocarbazole derivatives
liposomal preparations
liposome
indolocarbazole
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69738416T
Other languages
English (en)
Other versions
DE69738416T2 (de
Inventor
Yasuki Kato
Masahiro Yamauchi
Kunio Ito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of DE69738416D1 publication Critical patent/DE69738416D1/de
Publication of DE69738416T2 publication Critical patent/DE69738416T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE69738416T 1996-06-18 1997-06-12 Liposomale zubereitungen von indolocarbazol-derivaten Expired - Fee Related DE69738416T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP15645996 1996-06-18
JP15645996 1996-06-18
PCT/JP1997/002033 WO1997048398A1 (en) 1996-06-18 1997-06-12 Liposome preparations of indolocarbazole derivatives

Publications (2)

Publication Number Publication Date
DE69738416D1 true DE69738416D1 (de) 2008-02-07
DE69738416T2 DE69738416T2 (de) 2008-12-11

Family

ID=15628218

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69738416T Expired - Fee Related DE69738416T2 (de) 1996-06-18 1997-06-12 Liposomale zubereitungen von indolocarbazol-derivaten

Country Status (10)

Country Link
US (1) US6045822A (de)
EP (1) EP0850646B1 (de)
AT (1) ATE381932T1 (de)
AU (1) AU718856B2 (de)
CA (1) CA2229892C (de)
DE (1) DE69738416T2 (de)
DK (1) DK0850646T3 (de)
ES (1) ES2296311T3 (de)
PT (1) PT850646E (de)
WO (1) WO1997048398A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6200968B1 (en) 1998-08-06 2001-03-13 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
US7795246B2 (en) 1998-08-06 2010-09-14 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
AU780194B2 (en) * 1999-06-24 2005-03-10 Kyowa Hakko Kirin Co., Ltd. Method of regulating leakage of drug encapsulated in liposomes
JP4623931B2 (ja) * 2000-12-07 2011-02-02 エンセラデュス、ファーマシューティカルズ、ベスローテン、フェンノートシャップ 炎症性疾患の治療用組成物
US7396852B2 (en) * 2005-11-16 2008-07-08 Xerox Corporation Compound having indolocarbazole moiety and divalent linkage
US20060124921A1 (en) * 2004-12-14 2006-06-15 Xerox Corporation Compound with indolocarbazole moieties and devices containing such compound
TWI468188B (zh) 2008-01-30 2015-01-11 Univ Tokushima Anti-cancer effect enhancers consisting of oxaliplatin liposomal preparations and anticancer agents comprising the formulation
JP5638204B2 (ja) * 2009-05-29 2014-12-10 国立大学法人 岡山大学 経口投与用リポソーム製剤およびその製造方法
WO2014025042A1 (ja) 2012-08-10 2014-02-13 大鵬薬品工業株式会社 安定なオキサリプラチン封入リポソーム水分散液及びその安定化方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0383919A4 (en) * 1988-02-04 1992-08-05 Kyowa Hakko Kogyo Co., Ltd. Staurosporin derivatives
US4952567A (en) * 1988-05-09 1990-08-28 City Of Hope Inhibition of lipogenesis
JP2694701B2 (ja) * 1989-08-24 1997-12-24 日本油脂株式会社 液体膜制癌剤
IL100833A0 (en) * 1991-02-20 1992-09-06 Greenwich Pharma Method for synthesis of ethereally substituted blocked monosaccharides
JPH07278016A (ja) * 1994-04-13 1995-10-24 Pola Chem Ind Inc 抗癌剤リポソーム製剤
EP0711556A1 (de) * 1994-11-09 1996-05-15 Ciba-Geigy Ag Intravenöse Lösungen für ein Staurosporinderivat

Also Published As

Publication number Publication date
US6045822A (en) 2000-04-04
WO1997048398A1 (en) 1997-12-24
EP0850646A4 (de) 2005-06-22
CA2229892C (en) 2003-01-07
CA2229892A1 (en) 1997-12-24
EP0850646A1 (de) 1998-07-01
DE69738416T2 (de) 2008-12-11
PT850646E (pt) 2008-03-31
AU718856B2 (en) 2000-04-20
DK0850646T3 (da) 2008-05-13
AU3106697A (en) 1998-01-07
ATE381932T1 (de) 2008-01-15
EP0850646B1 (de) 2007-12-26
ES2296311T3 (es) 2008-04-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee