DE69733209D1 - Verfahren zur stereoselektiven herstellung von nitro-enamin-verbindungen - Google Patents

Verfahren zur stereoselektiven herstellung von nitro-enamin-verbindungen

Info

Publication number
DE69733209D1
DE69733209D1 DE69733209T DE69733209T DE69733209D1 DE 69733209 D1 DE69733209 D1 DE 69733209D1 DE 69733209 T DE69733209 T DE 69733209T DE 69733209 T DE69733209 T DE 69733209T DE 69733209 D1 DE69733209 D1 DE 69733209D1
Authority
DE
Germany
Prior art keywords
stereoselective
nitro
manufacture
enamine compounds
enamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69733209T
Other languages
English (en)
Other versions
DE69733209T2 (de
Inventor
A Oliver-Shaffer
A Narayanan
E Resek
R Singam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69733209D1 publication Critical patent/DE69733209D1/de
Publication of DE69733209T2 publication Critical patent/DE69733209T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69733209T 1996-12-13 1997-12-12 Verfahren zur stereoselektiven herstellung von nitro-enamin-verbindungen Expired - Lifetime DE69733209T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US764866 1996-12-13
US08/764,866 US5801250A (en) 1996-12-13 1996-12-13 Process for the stereoselective production of nitro-enamine compounds
PCT/US1997/022791 WO1998025917A1 (en) 1996-12-13 1997-12-12 Process for the stereoselective production of nitro-enamine compounds

Publications (2)

Publication Number Publication Date
DE69733209D1 true DE69733209D1 (de) 2005-06-09
DE69733209T2 DE69733209T2 (de) 2006-02-16

Family

ID=25072014

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69733209T Expired - Lifetime DE69733209T2 (de) 1996-12-13 1997-12-12 Verfahren zur stereoselektiven herstellung von nitro-enamin-verbindungen

Country Status (10)

Country Link
US (1) US5801250A (de)
EP (1) EP0946537B1 (de)
JP (1) JP4491074B2 (de)
AT (1) ATE294789T1 (de)
CA (1) CA2272539C (de)
DE (1) DE69733209T2 (de)
DK (1) DK0946537T3 (de)
ES (1) ES2242985T3 (de)
PT (1) PT946537E (de)
WO (1) WO1998025917A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2259825C9 (ru) 2001-06-18 2006-04-10 БиоДием Лимитед Вещества, проявляющие антимикробную, антигрибковую, антипротозойную активности
PE20160221A1 (es) 2013-07-08 2016-05-22 Abbvie Inc Formas de dosificacion farmaceuticas estabilizadas que comprenden atrasentan
US8962675B1 (en) 2013-09-12 2015-02-24 Abbvie Inc. Atrasentan mandelate salts

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE219077T1 (de) * 1994-08-19 2002-06-15 Abbott Lab Endothelin antagoniste

Also Published As

Publication number Publication date
ES2242985T3 (es) 2005-11-16
US5801250A (en) 1998-09-01
CA2272539A1 (en) 1998-06-18
DE69733209T2 (de) 2006-02-16
ATE294789T1 (de) 2005-05-15
JP4491074B2 (ja) 2010-06-30
CA2272539C (en) 2006-06-13
EP0946537A1 (de) 1999-10-06
EP0946537B1 (de) 2005-05-04
PT946537E (pt) 2005-08-31
JP2001506238A (ja) 2001-05-15
DK0946537T3 (da) 2005-08-15
WO1998025917A1 (en) 1998-06-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition