DE69733086T2 - Pharmazeutische zusammensetzungen welche kukui nuss öl enthalten - Google Patents
Pharmazeutische zusammensetzungen welche kukui nuss öl enthalten Download PDFInfo
- Publication number
- DE69733086T2 DE69733086T2 DE69733086T DE69733086T DE69733086T2 DE 69733086 T2 DE69733086 T2 DE 69733086T2 DE 69733086 T DE69733086 T DE 69733086T DE 69733086 T DE69733086 T DE 69733086T DE 69733086 T2 DE69733086 T2 DE 69733086T2
- Authority
- DE
- Germany
- Prior art keywords
- stearate
- polyoxyl
- propylparaben
- isopropyl
- propylene glycol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 20
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 153
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims abstract description 110
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 claims abstract description 106
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 106
- 244000136475 Aleurites moluccana Species 0.000 claims abstract description 84
- 235000006667 Aleurites moluccana Nutrition 0.000 claims abstract description 84
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 claims abstract description 55
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 claims abstract description 55
- 229960002216 methylparaben Drugs 0.000 claims abstract description 55
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 claims abstract description 55
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 claims abstract description 53
- 229960003415 propylparaben Drugs 0.000 claims abstract description 53
- 229920002701 Polyoxyl 40 Stearate Polymers 0.000 claims abstract description 51
- 229940099429 polyoxyl 40 stearate Drugs 0.000 claims abstract description 51
- 235000019488 nut oil Nutrition 0.000 claims abstract description 47
- 239000010466 nut oil Substances 0.000 claims abstract description 47
- 229940008099 dimethicone Drugs 0.000 claims abstract description 43
- 239000004205 dimethyl polysiloxane Substances 0.000 claims abstract description 43
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims abstract description 43
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims abstract description 43
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims abstract description 39
- 239000008213 purified water Substances 0.000 claims abstract description 34
- -1 alcohols benzoate Chemical class 0.000 claims abstract description 30
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 29
- 239000004615 ingredient Substances 0.000 claims abstract description 28
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 claims abstract description 27
- 235000021355 Stearic acid Nutrition 0.000 claims abstract description 16
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims abstract description 16
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims abstract description 16
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- 229940073669 ceteareth 20 Drugs 0.000 claims abstract description 14
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims abstract description 13
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- 229940075529 glyceryl stearate Drugs 0.000 claims abstract description 13
- 229940100460 peg-100 stearate Drugs 0.000 claims abstract description 13
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- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 claims abstract description 10
- 229940055577 oleyl alcohol Drugs 0.000 claims abstract description 10
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 claims abstract description 10
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims abstract description 7
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims abstract description 7
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000005642 Oleic acid Substances 0.000 claims abstract description 7
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 claims abstract description 7
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229940074928 isopropyl myristate Drugs 0.000 claims abstract description 7
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims abstract description 7
- UJNOLBSYLSYIBM-WISYIIOYSA-N [(1r,2s,5r)-5-methyl-2-propan-2-ylcyclohexyl] (2r)-2-hydroxypropanoate Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)[C@@H](C)O UJNOLBSYLSYIBM-WISYIIOYSA-N 0.000 claims abstract description 5
- 229960004592 isopropanol Drugs 0.000 claims abstract description 4
- 229960002969 oleic acid Drugs 0.000 claims abstract description 4
- 229960004063 propylene glycol Drugs 0.000 claims description 50
- 239000002304 perfume Substances 0.000 claims description 37
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims description 30
- 239000000203 mixture Substances 0.000 claims description 29
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 claims description 22
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 14
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- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 10
- 229960005150 glycerol Drugs 0.000 claims description 10
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- 229920001285 xanthan gum Polymers 0.000 claims description 9
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- 235000010493 xanthan gum Nutrition 0.000 claims description 9
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 239000011787 zinc oxide Substances 0.000 claims description 5
- CIVCELMLGDGMKZ-UHFFFAOYSA-N 2,4-dichloro-6-methylpyridine-3-carboxylic acid Chemical compound CC1=CC(Cl)=C(C(O)=O)C(Cl)=N1 CIVCELMLGDGMKZ-UHFFFAOYSA-N 0.000 claims description 4
- 239000000739 antihistaminic agent Substances 0.000 claims description 4
- 239000003246 corticosteroid Substances 0.000 claims description 4
- 229960000525 diphenhydramine hydrochloride Drugs 0.000 claims description 4
- 229960004393 lidocaine hydrochloride Drugs 0.000 claims description 4
- YECIFGHRMFEPJK-UHFFFAOYSA-N lidocaine hydrochloride monohydrate Chemical compound O.[Cl-].CC[NH+](CC)CC(=O)NC1=C(C)C=CC=C1C YECIFGHRMFEPJK-UHFFFAOYSA-N 0.000 claims description 4
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 claims description 3
- 230000003444 anaesthetic effect Effects 0.000 claims description 3
- 230000000202 analgesic effect Effects 0.000 claims description 3
- 230000001387 anti-histamine Effects 0.000 claims description 3
- 229940121375 antifungal agent Drugs 0.000 claims description 3
- 235000013772 propylene glycol Nutrition 0.000 claims description 3
- 230000000843 anti-fungal effect Effects 0.000 claims description 2
- 230000003115 biocidal effect Effects 0.000 claims description 2
- 229930013930 alkaloid Natural products 0.000 claims 1
- 150000003797 alkaloid derivatives Chemical class 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 6
- 229940124597 therapeutic agent Drugs 0.000 abstract description 3
- 239000013543 active substance Substances 0.000 abstract description 2
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical compound O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 abstract 2
- UBHWBODXJBSFLH-UHFFFAOYSA-N hexadecan-1-ol;octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO.CCCCCCCCCCCCCCCCCCO UBHWBODXJBSFLH-UHFFFAOYSA-N 0.000 abstract 1
- 239000003921 oil Substances 0.000 description 52
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- WNWHHMBRJJOGFJ-UHFFFAOYSA-N 16-methylheptadecan-1-ol Chemical compound CC(C)CCCCCCCCCCCCCCCO WNWHHMBRJJOGFJ-UHFFFAOYSA-N 0.000 description 30
- NWGKJDSIEKMTRX-BFWOXRRGSA-N [(2r)-2-[(3r,4s)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] (z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)C1OC[C@H](O)[C@H]1O NWGKJDSIEKMTRX-BFWOXRRGSA-N 0.000 description 24
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- RMFFCSRJWUBPBJ-UHFFFAOYSA-N 15-hydroxypentadecyl benzoate Chemical compound OCCCCCCCCCCCCCCCOC(=O)C1=CC=CC=C1 RMFFCSRJWUBPBJ-UHFFFAOYSA-N 0.000 description 8
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- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 5
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- 125000001117 oleyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 4
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Classifications
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q13/00—Formulations or additives for perfume preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Botany (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3204896P | 1996-11-12 | 1996-11-12 | |
| US32048P | 1996-11-12 | ||
| PCT/US1997/018981 WO1998020852A1 (en) | 1996-11-12 | 1997-10-27 | Pharmaceutical compositions containing kukui nut oil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69733086D1 DE69733086D1 (de) | 2005-05-25 |
| DE69733086T2 true DE69733086T2 (de) | 2006-04-06 |
Family
ID=21862818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69733086T Expired - Fee Related DE69733086T2 (de) | 1996-11-12 | 1997-10-27 | Pharmazeutische zusammensetzungen welche kukui nuss öl enthalten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5853732A (enExample) |
| EP (1) | EP0954278B8 (enExample) |
| JP (1) | JP2001504463A (enExample) |
| AT (1) | ATE293434T1 (enExample) |
| AU (1) | AU4991497A (enExample) |
| DE (1) | DE69733086T2 (enExample) |
| ES (1) | ES2242218T3 (enExample) |
| WO (1) | WO1998020852A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10063341A1 (de) * | 2000-12-19 | 2002-06-20 | Beiersdorf Ag | Selbstschäumende oder schaumförmige Zubereitungen |
| DE10063342A1 (de) * | 2000-12-19 | 2002-06-20 | Beiersdorf Ag | Selbstschäumende oder schaumförmige Zubereitungen |
| DE10063340A1 (de) * | 2000-12-19 | 2002-08-29 | Beiersdorf Ag | Selbstschäumende oder schaumförmige Zubereitungen |
| DE10113046A1 (de) * | 2001-03-15 | 2002-09-26 | Beiersdorf Ag | Selbstschäumende schaumförmige Zubereitungen mit organischen Hydrokolliden und partikulären hydrophobisierten und/oder ölabsorbierenden Festkörpersubstanzen |
| DE10113051A1 (de) * | 2001-03-15 | 2002-09-19 | Beiersdorf Ag | Selbstschäumende oder schaumförmige Zubereitungen mit anorganischen Gelbildnern und partikulären hydrophoben und/oder hydrophobisierten und/oder ölabsorbierenden Festkörpersubstanzen |
| DE10113048A1 (de) * | 2001-03-15 | 2002-09-19 | Beiersdorf Ag | Selbstschäumende oder schaumförmige Zubereitungen mit partikulären hydrophoben und/oder hydrophobisierten und/oder ölabsorbierenden Festkörpersubstanzen |
| DE10113050A1 (de) * | 2001-03-15 | 2002-09-19 | Beiersdorf Ag | Selbstschäumende oder schaumförmige Zubereitungen organischen Hydrokolloiden |
| DE10113053A1 (de) * | 2001-03-15 | 2002-09-19 | Beiersdorf Ag | Selbstschäumende oder schaumförmige Zubereitungen mit anorganischen Gelbildnern und organischen Hydrololloiden |
| DE10113047A1 (de) * | 2001-03-15 | 2002-09-26 | Beiersdorf Ag | Selbstschäumende oder schaumförmige Zubereitungen mit anorganischen Gelbildnern |
| DE10113054A1 (de) * | 2001-03-15 | 2002-09-26 | Beiersdorf Ag | Selbstschäumende oder schaumförmige Zubereitungen mit anorganischen Gelbildnern, organischen Hydrokolloiden und partikulären hydrophoben und/oder hydrophobisierten und/oder ölabsorbierenden Festkörpersubstanzen |
| US20030017181A1 (en) | 2001-05-31 | 2003-01-23 | Rood Gloria A. | Dermatological compositions and methods |
| US7074832B2 (en) | 2001-09-24 | 2006-07-11 | Bradley Pharmaceuticals, Inc. | Compositions containing antimicrobials and urea for the treatment of dermatological disorders and methods for their use |
| US6429231B1 (en) * | 2001-09-24 | 2002-08-06 | Bradley Pharmaceuticals, Inc. | Compositions containing antimicrobials and urea for the treatment of dermatological disorders and methods for their use |
| CA2416305A1 (en) | 2002-01-31 | 2003-07-31 | Davies, John | Shaving, after-shave, and skin conditioning compositions |
| US6986896B2 (en) * | 2002-03-20 | 2006-01-17 | Bradley Pharmaceuticals, Inc. | Method of treating fungal conditions of the skin |
| US6673842B2 (en) * | 2002-03-20 | 2004-01-06 | Bradley Pharmaceuticals, Inc. | Method of treating onychomycosis |
| US6743417B2 (en) | 2002-04-22 | 2004-06-01 | Bradley Pharmaceuticals, Inc. | Method of treating onychomycosis with urea and an antioxidant |
| US20040091551A1 (en) * | 2002-11-13 | 2004-05-13 | Al-Karim Damji | Topical composition and application system |
| US20040156870A1 (en) * | 2003-02-11 | 2004-08-12 | Bradley Pharmaceuticals, Inc. | Use of urea as a method for improving the effectiveness of topical anti-inflammatory drugs |
| US8158138B1 (en) | 2004-05-20 | 2012-04-17 | Fougera Pharmaceuticals, Inc. | Urea compositions and their methods of manufacture |
| WO2006102004A2 (en) * | 2005-03-16 | 2006-09-28 | Taro Pharmaceuticals U.S.A., Inc. | A stable aqueous-based emulsion formulation comprising urea and salicylic acid and method of using same |
| GB0506141D0 (en) * | 2005-03-24 | 2005-05-04 | Transphase Ltd | A topical compostion and its uses |
| GB0506139D0 (en) * | 2005-03-24 | 2005-05-04 | Transphase Ltd | A transdermal topical composition and its uses |
| FR2889662B1 (fr) * | 2005-08-11 | 2011-01-14 | Galderma Res & Dev | Emulsion de type huile-dans-eau pour application topique en dermatologie |
| CA2641991A1 (en) * | 2006-02-09 | 2007-08-16 | Elevance Renewable Sciences, Inc. | Antimicrobial compositions, methods and systems |
| US7951232B2 (en) * | 2006-02-09 | 2011-05-31 | Elevance Renewable Sciences, Inc. | Surface coating compositions and methods |
| CA2675797A1 (en) * | 2007-01-16 | 2008-07-24 | Dermworx, Incorporated | Topical anesthetic for rapid local anesthesia and method of applying a topical anesthetic |
| US9283177B2 (en) * | 2007-01-16 | 2016-03-15 | Juventio, Llc | Topical anesthetic for rapid local anesthesia and method of applying a topical anesthetic |
| US9050293B2 (en) * | 2008-07-16 | 2015-06-09 | Juventio, Llc | Small molecule solubilization system |
| JP7465066B2 (ja) * | 2019-06-17 | 2024-04-10 | 小林製薬株式会社 | 乳化安定化剤 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4154823A (en) * | 1976-06-10 | 1979-05-15 | Schutt Steven R | Skin treatment compositions and methods of using same |
| US4525344A (en) * | 1983-08-15 | 1985-06-25 | Tutsky Ronald J | Skin care and shaving composition |
| US5213798A (en) * | 1990-02-16 | 1993-05-25 | Manikas John T | Antiviral agent derived from the hull of the kukui nut |
| US5720942A (en) * | 1992-06-01 | 1998-02-24 | Radical Products, Inc. | Two-phase tanning compositions and methods relating thereto |
| US5279817A (en) * | 1992-10-02 | 1994-01-18 | Ricardo Franco | Suntanning oil formulation containing annatto |
| JP3577721B2 (ja) * | 1993-07-14 | 2004-10-13 | 三省製薬株式会社 | 皮膚外用剤 |
| US5626155C1 (en) * | 1993-10-21 | 2001-05-22 | Robert E Saute | Method of creating fragrances in situ |
| DE4405127A1 (de) * | 1994-02-18 | 1995-08-31 | Henkel Kgaa | Haarbehandlungsmittel |
| US5656312A (en) * | 1994-09-02 | 1997-08-12 | Erasmus; Udo | Dietary food supplement and method of preparing |
| US5560917A (en) * | 1995-02-01 | 1996-10-01 | Maybelline Intermediate Company | Cosmetic makeup composition |
-
1997
- 1997-10-27 JP JP52257998A patent/JP2001504463A/ja not_active Ceased
- 1997-10-27 WO PCT/US1997/018981 patent/WO1998020852A1/en not_active Ceased
- 1997-10-27 US US08/958,273 patent/US5853732A/en not_active Expired - Fee Related
- 1997-10-27 EP EP97912824A patent/EP0954278B8/en not_active Expired - Lifetime
- 1997-10-27 ES ES97912824T patent/ES2242218T3/es not_active Expired - Lifetime
- 1997-10-27 DE DE69733086T patent/DE69733086T2/de not_active Expired - Fee Related
- 1997-10-27 AU AU49914/97A patent/AU4991497A/en not_active Abandoned
- 1997-10-27 AT AT97912824T patent/ATE293434T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0954278A1 (en) | 1999-11-10 |
| DE69733086D1 (de) | 2005-05-25 |
| JP2001504463A (ja) | 2001-04-03 |
| EP0954278B1 (en) | 2005-04-20 |
| AU4991497A (en) | 1998-06-03 |
| ATE293434T1 (de) | 2005-05-15 |
| US5853732A (en) | 1998-12-29 |
| WO1998020852A1 (en) | 1998-05-22 |
| EP0954278B8 (en) | 2005-06-15 |
| ES2242218T3 (es) | 2005-11-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: PHARMACIA & UPJOHN CO. LLC, KALAMAZOO, MICH., US |
|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: PHARMACIA & UPJOHN CO. LLC, WILMINGTON, DEL., US |
|
| 8339 | Ceased/non-payment of the annual fee |