DE69730753D1 - Rotierende atherektomievorrichtung mit radial expandierbarer antriebsmaschinenkupplung - Google Patents
Rotierende atherektomievorrichtung mit radial expandierbarer antriebsmaschinenkupplungInfo
- Publication number
- DE69730753D1 DE69730753D1 DE69730753T DE69730753T DE69730753D1 DE 69730753 D1 DE69730753 D1 DE 69730753D1 DE 69730753 T DE69730753 T DE 69730753T DE 69730753 T DE69730753 T DE 69730753T DE 69730753 D1 DE69730753 D1 DE 69730753D1
- Authority
- DE
- Germany
- Prior art keywords
- cartridge
- socket
- athereectomy
- rotating
- drive coupling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B17/320758—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16D—COUPLINGS FOR TRANSMITTING ROTATION; CLUTCHES; BRAKES
- F16D43/00—Automatic clutches
- F16D43/02—Automatic clutches actuated entirely mechanically
- F16D43/04—Automatic clutches actuated entirely mechanically controlled by angular speed
- F16D43/14—Automatic clutches actuated entirely mechanically controlled by angular speed with centrifugal masses actuating the clutching members directly in a direction which has at least a radial component; with centrifugal masses themselves being the clutching members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/0046—Surgical instruments, devices or methods, e.g. tourniquets with a releasable handle; with handle and operating part separable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00477—Coupling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00681—Aspects not otherwise provided for
- A61B2017/00685—Archimedes screw
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
- A61B2017/22049—Means for locking the guide wire in the catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22072—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an instrument channel, e.g. for replacing one instrument by the other
- A61B2017/22074—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an instrument channel, e.g. for replacing one instrument by the other the instrument being only slidable in a channel, e.g. advancing optical fibre through a channel
- A61B2017/22075—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an instrument channel, e.g. for replacing one instrument by the other the instrument being only slidable in a channel, e.g. advancing optical fibre through a channel with motorized advancing or retracting means
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- General Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Mechanical Engineering (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Soil Working Implements (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US957942 | 1997-10-27 | ||
US08/957,942 US6129734A (en) | 1997-01-21 | 1997-10-27 | Rotational atherectomy device with radially expandable prime mover coupling |
PCT/US1997/019835 WO1999021492A1 (en) | 1997-10-27 | 1997-10-31 | Rotational atherectomy device with radially expandable prime mover coupling |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69730753D1 true DE69730753D1 (de) | 2004-10-21 |
DE69730753T2 DE69730753T2 (de) | 2005-09-22 |
Family
ID=25500376
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69730753T Expired - Lifetime DE69730753T2 (de) | 1997-10-27 | 1997-10-31 | Rotierende atherektomievorrichtung mit radial expandierbarer antriebsmaschinenkupplung |
Country Status (7)
Country | Link |
---|---|
US (1) | US6129734A (de) |
EP (1) | EP1024756B1 (de) |
AT (1) | ATE275875T1 (de) |
AU (1) | AU742157B2 (de) |
CA (1) | CA2316240C (de) |
DE (1) | DE69730753T2 (de) |
WO (1) | WO1999021492A1 (de) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6077282A (en) * | 1997-10-27 | 2000-06-20 | Shturman Cardiology Systems, Inc. | Rotational atherectomy device with exchangeable drive shaft cartridge |
US8328829B2 (en) | 1999-08-19 | 2012-12-11 | Covidien Lp | High capacity debulking catheter with razor edge cutting window |
US7771444B2 (en) | 2000-12-20 | 2010-08-10 | Fox Hollow Technologies, Inc. | Methods and devices for removing material from a body lumen |
US6299622B1 (en) | 1999-08-19 | 2001-10-09 | Fox Hollow Technologies, Inc. | Atherectomy catheter with aligned imager |
US7708749B2 (en) | 2000-12-20 | 2010-05-04 | Fox Hollow Technologies, Inc. | Debulking catheters and methods |
US7713279B2 (en) | 2000-12-20 | 2010-05-11 | Fox Hollow Technologies, Inc. | Method and devices for cutting tissue |
US7174240B2 (en) | 2001-10-19 | 2007-02-06 | Cardiovascular Systems, Inc. | Control system for rotational angioplasty device |
US6852118B2 (en) * | 2001-10-19 | 2005-02-08 | Shturman Cardiology Systems, Inc. | Self-indexing coupling for rotational angioplasty device |
US8246640B2 (en) | 2003-04-22 | 2012-08-21 | Tyco Healthcare Group Lp | Methods and devices for cutting tissue at a vascular location |
EP1819304B1 (de) | 2004-12-09 | 2023-01-25 | Twelve, Inc. | Aortaklappenreparatur |
US20070276419A1 (en) | 2006-05-26 | 2007-11-29 | Fox Hollow Technologies, Inc. | Methods and devices for rotating an active element and an energy emitter on a catheter |
ES2498798T3 (es) * | 2006-09-13 | 2014-09-25 | Vascular Insights Llc | Dispositivo de tratamiento vascular |
US8784440B2 (en) | 2008-02-25 | 2014-07-22 | Covidien Lp | Methods and devices for cutting tissue |
BRPI0920206A2 (pt) | 2008-10-13 | 2015-12-22 | Tyco Healthcare | dispositivos e métodos para manipulação de um eixo de cateter |
CN102625673B (zh) | 2009-04-29 | 2014-12-24 | 泰科保健集团有限合伙公司 | 用于切割和研磨组织的方法及装置 |
EP2429423B1 (de) | 2009-05-14 | 2015-11-11 | Covidien LP | Leicht zu reinigende atherektomiekatheter |
WO2010138499A1 (en) * | 2009-05-25 | 2010-12-02 | Stereotaxis, Inc. | Remote manipulator device |
EP2282070B1 (de) * | 2009-08-06 | 2012-10-17 | ECP Entwicklungsgesellschaft mbH | Kathetereinrichtung mit einer Ankopplungseinrichtung für eine Antriebseinrichtung |
US20110087254A1 (en) * | 2009-10-09 | 2011-04-14 | Cardiovascular Systems, Inc. | Rotational atherectomy device with keyed exchangeable drive shaft |
US9962229B2 (en) | 2009-10-12 | 2018-05-08 | Corindus, Inc. | System and method for navigating a guide wire |
WO2011068932A1 (en) | 2009-12-02 | 2011-06-09 | Fox Hollow Technologies, Inc. | Methods and devices for cutting tissue |
CA2783301C (en) | 2009-12-11 | 2015-02-24 | Tyco Healthcare Group Lp | Material removal device having improved material capture efficiency and methods of use |
US10952764B2 (en) | 2010-05-04 | 2021-03-23 | Samuel Shiber | Rotary catheter drive unit containing seal-sets |
US20150094733A1 (en) | 2010-05-04 | 2015-04-02 | Samuel Shiber | Rotary catheter drive unit containing seal-sets |
US9907567B2 (en) | 2010-05-04 | 2018-03-06 | Samuel Shiber | Mechanical — pharmaceutical system for opening obstructed bodily vessels |
US9119662B2 (en) | 2010-06-14 | 2015-09-01 | Covidien Lp | Material removal device and method of use |
BR112013009835A2 (pt) | 2010-10-28 | 2016-07-26 | Covidien Lp | dispositivo para a remoção de material e método de uso |
BR112013011632A2 (pt) | 2010-11-11 | 2016-08-09 | Covidien Lp | cateteres de citorredução flexíveis com imagiologia e métodos de uso e fabricação |
US9585667B2 (en) | 2010-11-15 | 2017-03-07 | Vascular Insights Llc | Sclerotherapy catheter with lumen having wire rotated by motor and simultaneous withdrawal from vein |
US9421098B2 (en) | 2010-12-23 | 2016-08-23 | Twelve, Inc. | System for mitral valve repair and replacement |
CN107647939A (zh) | 2011-06-21 | 2018-02-02 | 托尔福公司 | 人工心脏瓣膜装置及相关系统 |
US9700347B2 (en) * | 2011-08-17 | 2017-07-11 | Samuel Shiber | Adaptive rotary catheter for opening obstructed bodily vessels |
EP2750862B1 (de) | 2011-09-01 | 2016-07-06 | Covidien LP | Katheter mit spiralförmiger antriebswelle und herstellungsverfahren |
US9763780B2 (en) | 2011-10-19 | 2017-09-19 | Twelve, Inc. | Devices, systems and methods for heart valve replacement |
EP4252714A3 (de) | 2011-10-19 | 2023-12-20 | Twelve, Inc. | Vorrichtung für den ersatz einer herzklappe |
EA201400481A1 (ru) | 2011-10-19 | 2014-10-30 | Твелв, Инк. | Искусственные сердечно-клапанные устройства, искусственные митральные клапаны и соответствующие системы и способы |
US11202704B2 (en) | 2011-10-19 | 2021-12-21 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9655722B2 (en) | 2011-10-19 | 2017-05-23 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9039757B2 (en) | 2011-10-19 | 2015-05-26 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
US9579198B2 (en) | 2012-03-01 | 2017-02-28 | Twelve, Inc. | Hydraulic delivery systems for prosthetic heart valve devices and associated methods |
US9532844B2 (en) | 2012-09-13 | 2017-01-03 | Covidien Lp | Cleaning device for medical instrument and method of use |
US9943329B2 (en) | 2012-11-08 | 2018-04-17 | Covidien Lp | Tissue-removing catheter with rotatable cutter |
CN105246431B (zh) | 2013-05-20 | 2018-04-06 | 托尔福公司 | 可植入心脏瓣膜装置、二尖瓣修复装置以及相关系统和方法 |
US9724123B2 (en) | 2013-07-25 | 2017-08-08 | Cardiovascular Systems, Inc. | Rotational atherectomy device with exchangeable drive shaft and meshing gears |
US9907566B2 (en) | 2013-07-25 | 2018-03-06 | Cardiovascualar Systems, Inc. | Rotational atherectomy device with exchangeable drive shaft and meshing gears |
US9844390B2 (en) | 2013-07-25 | 2017-12-19 | Cardiovascular Systems, Inc. | Rotational atherectomy device with exchangeable drive shaft and meshing gears |
US9439674B2 (en) | 2013-07-25 | 2016-09-13 | Cardiovascular Systems, Inc. | Rotational atherectomy device with exchangeable drive shaft and meshing gears |
US9924964B2 (en) | 2013-07-25 | 2018-03-27 | Cardiovascular Systems, Inc. | Rotational atherectomy device with exchangeable drive shaft and meshing gears |
US9750526B2 (en) | 2013-07-25 | 2017-09-05 | Cardiovascular Systems, Inc. | Rotational atherectomy device with exchangeable drive shaft and meshing gears |
US20150080795A1 (en) | 2013-07-26 | 2015-03-19 | Cardiovascular Systems, Inc. | Devices, systems and methods for performing atherectomy and subsequent balloon angioplasty without exchanging devices |
US9468457B2 (en) | 2013-09-30 | 2016-10-18 | Cardiovascular Systems, Inc. | Atherectomy device with eccentric crown |
USD766433S1 (en) | 2013-11-04 | 2016-09-13 | Cardiovascular Systems, Inc. | Eccentric crown |
EP3957259B1 (de) | 2014-03-12 | 2023-09-27 | Boston Scientific Limited | Infusionsgeschmierter atherektomiekatheter |
WO2015200702A1 (en) | 2014-06-27 | 2015-12-30 | Covidien Lp | Cleaning device for catheter and catheter including the same |
US10405878B2 (en) | 2014-07-25 | 2019-09-10 | Boston Scientific Scimed, Inc. | Rotatable medical device |
JP2017531503A (ja) * | 2014-10-14 | 2017-10-26 | カーディオバスキュラー システムズ, インコーポレイテッド | 交換可能駆動軸および噛合い歯車を有する回転アテローム切除装置 |
WO2016089847A1 (en) | 2014-12-04 | 2016-06-09 | Boston Scientific Scimed, Inc. | Rotatable medical device |
CN111494008A (zh) | 2014-12-05 | 2020-08-07 | 科林达斯公司 | 用于引导导线的系统和方法 |
US10314667B2 (en) | 2015-03-25 | 2019-06-11 | Covidien Lp | Cleaning device for cleaning medical instrument |
US10413318B2 (en) * | 2015-06-01 | 2019-09-17 | Cardiovascular Systems, Inc. | Rotational systems comprising a polymer driveshaft |
US10292721B2 (en) | 2015-07-20 | 2019-05-21 | Covidien Lp | Tissue-removing catheter including movable distal tip |
WO2017035002A1 (en) | 2015-08-21 | 2017-03-02 | Twelve Inc. | Implantable heart valve devices, mitral valve repair devices and associated systems and methods |
US10314664B2 (en) | 2015-10-07 | 2019-06-11 | Covidien Lp | Tissue-removing catheter and tissue-removing element with depth stop |
EP3448316B1 (de) | 2016-04-29 | 2023-03-29 | Medtronic Vascular Inc. | Herzklappenprothesenvorrichtungen mit angebundenen ankern |
US10575950B2 (en) | 2017-04-18 | 2020-03-03 | Twelve, Inc. | Hydraulic systems for delivering prosthetic heart valve devices and associated methods |
US10702378B2 (en) | 2017-04-18 | 2020-07-07 | Twelve, Inc. | Prosthetic heart valve device and associated systems and methods |
US10433961B2 (en) | 2017-04-18 | 2019-10-08 | Twelve, Inc. | Delivery systems with tethers for prosthetic heart valve devices and associated methods |
US11690645B2 (en) | 2017-05-03 | 2023-07-04 | Medtronic Vascular, Inc. | Tissue-removing catheter |
WO2018204704A1 (en) | 2017-05-03 | 2018-11-08 | Medtronic Vascular, Inc. | Tissue-removing catheter |
US10792151B2 (en) | 2017-05-11 | 2020-10-06 | Twelve, Inc. | Delivery systems for delivering prosthetic heart valve devices and associated methods |
US10646338B2 (en) | 2017-06-02 | 2020-05-12 | Twelve, Inc. | Delivery systems with telescoping capsules for deploying prosthetic heart valve devices and associated methods |
US10709591B2 (en) | 2017-06-06 | 2020-07-14 | Twelve, Inc. | Crimping device and method for loading stents and prosthetic heart valves |
US10786352B2 (en) | 2017-07-06 | 2020-09-29 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
US10729541B2 (en) | 2017-07-06 | 2020-08-04 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
US10588656B2 (en) | 2017-11-10 | 2020-03-17 | Penumbra, Inc. | Thrombectomy catheter |
JP2021087462A (ja) * | 2018-03-23 | 2021-06-10 | テルモ株式会社 | 医療デバイス |
JP7222978B2 (ja) * | 2018-03-29 | 2023-02-15 | テルモ株式会社 | 医療デバイス |
EP4434477A2 (de) | 2018-11-16 | 2024-09-25 | Medtronic Vascular Inc. | Gewebeentfernungskatheter |
US11819236B2 (en) | 2019-05-17 | 2023-11-21 | Medtronic Vascular, Inc. | Tissue-removing catheter |
WO2021201937A1 (en) * | 2020-03-31 | 2021-10-07 | Dib UltraNav Medical LLC | Handle assembly for medical devices |
DE102021109023B4 (de) | 2021-04-12 | 2024-08-14 | Karl Storz Se & Co. Kg | Endoskop, insbesondere medizinisches Einweg-Endoskop |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1851146A (en) * | 1930-03-20 | 1932-03-29 | Continental Illinois Bank & Tr | Automatic clutch |
FR761398A (fr) * | 1932-09-30 | 1934-03-17 | Embrayage à friction | |
US3712438A (en) * | 1971-03-15 | 1973-01-23 | Emerson Electric Co | Centrifugal friction clutch |
US3937222A (en) * | 1973-11-09 | 1976-02-10 | Surgical Design Corporation | Surgical instrument employing cutter means |
US4679557A (en) * | 1984-09-10 | 1987-07-14 | E. R. Squibb & Sons, Inc. | Electrodynamic transluminal angioplasty system |
CA1293663C (en) | 1986-01-06 | 1991-12-31 | David Christopher Auth | Transluminal microdissection device |
EP0244058B1 (de) * | 1986-02-28 | 1992-09-23 | Devices For Vascular Intervention, Inc. | Motor-Antriebseinheit für einen Arteriektomie-Katheter |
US5314407A (en) | 1986-11-14 | 1994-05-24 | Heart Technology, Inc. | Clinically practical rotational angioplasty system |
US4857046A (en) * | 1987-10-21 | 1989-08-15 | Cordis Corporation | Drive catheter having helical pump drive shaft |
ES2023004B3 (es) * | 1987-12-14 | 1991-12-16 | Rockwell Automotive Body Systems-France En Abrege:Rockwell Abs-France | Embrague centrifugo para accionador de condena de una cerradura de puerta de vehiculo automovil |
US5360432A (en) | 1992-10-16 | 1994-11-01 | Shturman Cardiology Systems, Inc. | Abrasive drive shaft device for directional rotational atherectomy |
US5501694A (en) * | 1992-11-13 | 1996-03-26 | Scimed Life Systems, Inc. | Expandable intravascular occlusion material removal devices and methods of use |
US5437678A (en) * | 1992-11-30 | 1995-08-01 | Neomedix Corporation | Ophthalmic lens removal method and apparatus |
US5584843A (en) * | 1994-12-20 | 1996-12-17 | Boston Scientific Corporation | Shaped wire multi-burr rotational ablation device |
NL1000163C2 (en) * | 1995-04-18 | 1996-10-21 | Cordis Europ | Catheter with pumping action |
US5766190A (en) * | 1995-05-24 | 1998-06-16 | Boston Scientific Corporation Northwest Technology Center, Inc. | Connectable driveshaft system |
US5681336A (en) * | 1995-09-07 | 1997-10-28 | Boston Scientific Corporation | Therapeutic device for treating vien graft lesions |
US5766192A (en) * | 1995-10-20 | 1998-06-16 | Zacca; Nadim M. | Atherectomy, angioplasty and stent method and apparatus |
-
1997
- 1997-10-27 US US08/957,942 patent/US6129734A/en not_active Expired - Lifetime
- 1997-10-31 WO PCT/US1997/019835 patent/WO1999021492A1/en active IP Right Grant
- 1997-10-31 CA CA002316240A patent/CA2316240C/en not_active Expired - Lifetime
- 1997-10-31 AU AU51593/98A patent/AU742157B2/en not_active Expired
- 1997-10-31 DE DE69730753T patent/DE69730753T2/de not_active Expired - Lifetime
- 1997-10-31 EP EP97946423A patent/EP1024756B1/de not_active Expired - Lifetime
- 1997-10-31 AT AT97946423T patent/ATE275875T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1024756A1 (de) | 2000-08-09 |
US6129734A (en) | 2000-10-10 |
CA2316240C (en) | 2007-02-13 |
AU742157B2 (en) | 2001-12-20 |
CA2316240A1 (en) | 1999-05-06 |
WO1999021492A1 (en) | 1999-05-06 |
EP1024756B1 (de) | 2004-09-15 |
AU5159398A (en) | 1999-05-17 |
DE69730753T2 (de) | 2005-09-22 |
ATE275875T1 (de) | 2004-10-15 |
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