DE69718968D1 - 3-(bis-substituierte-phenylmethylen)oxindol-derivate - Google Patents

3-(bis-substituierte-phenylmethylen)oxindol-derivate

Info

Publication number
DE69718968D1
DE69718968D1 DE69718968T DE69718968T DE69718968D1 DE 69718968 D1 DE69718968 D1 DE 69718968D1 DE 69718968 T DE69718968 T DE 69718968T DE 69718968 T DE69718968 T DE 69718968T DE 69718968 D1 DE69718968 D1 DE 69718968D1
Authority
DE
Germany
Prior art keywords
prevention
treatment
phenylmethylene
bis
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69718968T
Other languages
English (en)
Other versions
DE69718968T2 (de
Inventor
Atsushi Sato
Tetsuji Asao
Yuichi Hagiwara
Makoto Kitade
Yasundo Yamazaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69718968D1 publication Critical patent/DE69718968D1/de
Publication of DE69718968T2 publication Critical patent/DE69718968T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
DE69718968T 1996-01-17 1997-01-16 3-(bis-substituierte-phenylmethylen)oxindol-derivate Expired - Fee Related DE69718968T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP569396 1996-01-17
JP1763696 1996-02-02
PCT/JP1997/000066 WO1997026242A1 (fr) 1996-01-17 1997-01-16 Derives de 3-(bis-phenylmethylene substitue) oxindole

Publications (2)

Publication Number Publication Date
DE69718968D1 true DE69718968D1 (de) 2003-03-20
DE69718968T2 DE69718968T2 (de) 2003-10-09

Family

ID=26339674

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69718968T Expired - Fee Related DE69718968T2 (de) 1996-01-17 1997-01-16 3-(bis-substituierte-phenylmethylen)oxindol-derivate

Country Status (8)

Country Link
US (1) US5965600A (de)
EP (1) EP0816338B1 (de)
KR (1) KR100281867B1 (de)
AT (1) ATE232515T1 (de)
AU (1) AU702045B2 (de)
CA (1) CA2214744C (de)
DE (1) DE69718968T2 (de)
WO (1) WO1997026242A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1098902A4 (de) 1998-07-23 2002-07-24 Yeda Res & Dev Behandlung von autoimmunkrankheiten mittels copolymer 1 und ähnlichen copolymeren und peptiden
ES2527760T3 (es) * 1998-07-23 2015-01-29 Yeda Research And Development Co., Ltd. Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos
US6800287B2 (en) * 1998-09-25 2004-10-05 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
AU767138B2 (en) 1998-12-17 2003-10-30 F. Hoffmann-La Roche Ag 4,5-pyrazinoxindoles as protein kinase inhibitors
US7022663B2 (en) * 2000-02-18 2006-04-04 Yeda Research And Development Co., Ltd. Oral, nasal and pulmonary dosage formulations of copolymer 1
US20020077278A1 (en) 2000-06-05 2002-06-20 Yong V. Wee Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
WO2002076503A1 (en) * 2000-06-20 2002-10-03 Mayo Foundation For Medical Education And Research Treatment of central nervous system diseases by antibodies against glatiramer acetate
EP1459065B1 (de) * 2001-12-04 2010-07-28 Teva Pharmaceutical Industries, Ltd. Verfahren zur messung der wirkstärke von glatirameracetat
CN103274988B (zh) * 2013-06-20 2016-04-13 河北大学 3-(氰基-p-硝基苯甲撑基)-2-吲哚酮衍生物及其合成方法和用途
CA3011639A1 (en) 2016-01-20 2017-07-27 Chemocentryx, Inc. 2-oxindole compounds
CN108484474B (zh) * 2018-04-04 2020-09-22 华南理工大学 具有聚集诱导发光性质的发光材料及其制备与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3413299A (en) * 1963-07-11 1968-11-26 Upjohn Co 3', 3'-di-substituted[spiro-indoline-3, 2'-oxiran]-2 ones and derivatives
GB1101794A (en) * 1965-04-28 1968-01-31 Upjohn Co Improvements in or relating to new substituted oxindoles and the manufacture thereof
US3428649A (en) * 1968-01-23 1969-02-18 Mcneilab Inc Oxindole derivatives
JPS60222415A (ja) * 1984-04-20 1985-11-07 Nippon Iyakuhin Kogyo Kk 抗炎症剤

Also Published As

Publication number Publication date
WO1997026242A1 (fr) 1997-07-24
KR100281867B1 (ko) 2001-02-15
AU1398797A (en) 1997-08-11
DE69718968T2 (de) 2003-10-09
AU702045B2 (en) 1999-02-11
EP0816338A1 (de) 1998-01-07
ATE232515T1 (de) 2003-02-15
EP0816338A4 (de) 2001-04-11
US5965600A (en) 1999-10-12
CA2214744C (en) 2002-12-24
CA2214744A1 (en) 1997-07-24
EP0816338B1 (de) 2003-02-12
KR19980703022A (ko) 1998-09-05

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee