DE69714081T2 - Augentropfen enthaltend ein loratidinmetabolit - Google Patents

Augentropfen enthaltend ein loratidinmetabolit

Info

Publication number
DE69714081T2
DE69714081T2 DE69714081T DE69714081T DE69714081T2 DE 69714081 T2 DE69714081 T2 DE 69714081T2 DE 69714081 T DE69714081 T DE 69714081T DE 69714081 T DE69714081 T DE 69714081T DE 69714081 T2 DE69714081 T2 DE 69714081T2
Authority
DE
Germany
Prior art keywords
eye drops
drops containing
loratidine
metabolite
loratidine metabolite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69714081T
Other languages
English (en)
Other versions
DE69714081D1 (de
Inventor
Takashi Fujimoto
Kimiya Okazaki
Hiroshi Kami
Koichiro Kase
Eiko Yoshizawa
Takeshi Shibahara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD KK
Original Assignee
Schering Plough KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Plough KK filed Critical Schering Plough KK
Publication of DE69714081D1 publication Critical patent/DE69714081D1/de
Application granted granted Critical
Publication of DE69714081T2 publication Critical patent/DE69714081T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
DE69714081T 1997-04-25 1997-04-25 Augentropfen enthaltend ein loratidinmetabolit Expired - Lifetime DE69714081T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP1997/001450 WO1998048803A1 (fr) 1997-04-25 1997-04-25 Collyres

Publications (2)

Publication Number Publication Date
DE69714081D1 DE69714081D1 (de) 2002-08-22
DE69714081T2 true DE69714081T2 (de) 2002-11-14

Family

ID=14180460

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69714081T Expired - Lifetime DE69714081T2 (de) 1997-04-25 1997-04-25 Augentropfen enthaltend ein loratidinmetabolit

Country Status (7)

Country Link
EP (1) EP0978281B1 (de)
AT (1) ATE220546T1 (de)
AU (1) AU2407597A (de)
CA (1) CA2288726C (de)
DE (1) DE69714081T2 (de)
ES (1) ES2180976T3 (de)
WO (1) WO1998048803A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1214071A2 (de) * 1999-09-22 2002-06-19 Schering Corporation Behandlung von entzündlichen und allergischen zuständen mit desloratadine
US6635654B1 (en) * 2003-01-09 2003-10-21 Allergan, Inc. Ophthalmic compositions containing loratadine
EP1778195A2 (de) * 2004-07-16 2007-05-02 Cipla Limited Anti-histaminische zusammensetzung
CA2591706A1 (en) 2004-12-22 2006-06-29 Schering Corporation Pharmaceutical formulations
JP6704721B2 (ja) * 2014-12-12 2020-06-03 興和株式会社 水性の組成物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU570306B2 (en) * 1984-02-15 1988-03-10 Schering Corporation 8-chloro-6, 11-dihydro-11-(4-piperidylidene)-5h-benzo (5,6) cyclohepta (1,2-b) pyridine and its salts.
DE3677842D1 (de) * 1985-05-13 1991-04-11 Schering Corp Verfahren zur herstellung von piperidyliden-dihydrodibenzo(a,d)zykloheptenen und deren azoderivate, so hergestellte verbindungen und ihre anwendung zur vorbereitung von heilmitteln.
US5019591A (en) * 1989-02-17 1991-05-28 Pennsylvania Research Corporation Method for treating retinopathy and other small vessel disorders associated with diabetes
AU636685B2 (en) * 1989-12-18 1993-05-06 Alcon Laboratories, Inc. Compositions of antiallergics and antihistamines and methods for their use
JP3256997B2 (ja) * 1990-08-30 2002-02-18 千寿製薬株式会社 安定な水性製剤
CA2052950A1 (en) * 1990-10-10 1992-04-11 David P. Evitts Aqueous ophthalmic microemulsions of tepoxalin
JP2811036B2 (ja) * 1992-05-26 1998-10-15 参天製薬株式会社 ビタミンｅ点眼剤
DE4442999A1 (de) * 1994-12-02 1996-06-05 Hexal Pharma Gmbh Pharmazeutische Zusammensetzung mit einem aktiven Loratidin-Metaboliten
JPH09124484A (ja) * 1995-10-27 1997-05-13 Schering Purau Kk 点眼剤
US5900421A (en) * 1997-02-11 1999-05-04 Sepracor Inc. Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine

Also Published As

Publication number Publication date
WO1998048803A1 (fr) 1998-11-05
ES2180976T3 (es) 2003-02-16
EP0978281A1 (de) 2000-02-09
CA2288726C (en) 2008-04-01
ATE220546T1 (de) 2002-08-15
DE69714081D1 (de) 2002-08-22
CA2288726A1 (en) 1998-11-05
EP0978281A4 (de) 2000-06-21
AU2407597A (en) 1998-11-24
EP0978281B1 (de) 2002-07-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PATENTANWAELTE ISENBRUCK BOESL HOERSCHLER WICHMANN HU