DE69712036D1 - Neue verabreichung von thrombopoietin - Google Patents

Neue verabreichung von thrombopoietin

Info

Publication number
DE69712036D1
DE69712036D1 DE69712036T DE69712036T DE69712036D1 DE 69712036 D1 DE69712036 D1 DE 69712036D1 DE 69712036 T DE69712036 T DE 69712036T DE 69712036 T DE69712036 T DE 69712036T DE 69712036 D1 DE69712036 D1 DE 69712036D1
Authority
DE
Germany
Prior art keywords
thrombopoietin
administration
new
low
materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69712036T
Other languages
English (en)
Other versions
DE69712036T2 (de
Inventor
R Thomas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DE69712036D1 publication Critical patent/DE69712036D1/de
Publication of DE69712036T2 publication Critical patent/DE69712036T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69712036T 1996-01-25 1997-01-13 Neue verabreichung von thrombopoietin Expired - Lifetime DE69712036T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US59192596A 1996-01-25 1996-01-25
US64144396A 1996-04-29 1996-04-29
US08/697,631 US5879673A (en) 1996-01-25 1996-08-28 Administration of thrombopoietin on a single day only
PCT/US1997/000438 WO1997026907A1 (en) 1996-01-25 1997-01-13 Novel administration of thrombopoietin

Publications (2)

Publication Number Publication Date
DE69712036D1 true DE69712036D1 (de) 2002-05-23
DE69712036T2 DE69712036T2 (de) 2002-11-28

Family

ID=27416624

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69712036T Expired - Lifetime DE69712036T2 (de) 1996-01-25 1997-01-13 Neue verabreichung von thrombopoietin
DE69739050T Expired - Lifetime DE69739050D1 (de) 1996-01-25 1997-01-13 Verwendung von Thrombopoietin als Medikament zur Therapie und Vorbeugung der Thrombocytopenie

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69739050T Expired - Lifetime DE69739050D1 (de) 1996-01-25 1997-01-13 Verwendung von Thrombopoietin als Medikament zur Therapie und Vorbeugung der Thrombocytopenie

Country Status (11)

Country Link
US (1) US5879673A (de)
EP (2) EP0876152B1 (de)
JP (1) JP2000504325A (de)
AT (2) ATE411039T1 (de)
AU (1) AU711639B2 (de)
CA (1) CA2242417A1 (de)
DE (2) DE69712036T2 (de)
DK (2) DK1201246T3 (de)
ES (2) ES2315255T3 (de)
PT (1) PT876152E (de)
WO (1) WO1997026907A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100408229B1 (ko) * 1996-10-04 2003-12-01 암겐 인코포레이티드 Ｍｐｌ 리간드를 함유하는 제약학적 조성물
AU2006201129B2 (en) * 1997-05-21 2008-03-13 Genentech, Inc. Novel administration of thrombopoietin
WO1998052598A1 (en) * 1997-05-21 1998-11-26 Genentech, Inc. Novel administration of thrombopoietin
WO1999011262A1 (en) * 1997-09-02 1999-03-11 Roche Diagnostics Gmbh Mpl-receptor ligands, process for their preparation, medicaments containing them and their use for the treatment and prevention of thrombocytopaenia and anaemia
US6776984B1 (en) 1999-08-20 2004-08-17 George R. Schwartz Induced regeneration and repair of damaged neurons and nerve axon myelin
US7582311B1 (en) 1999-10-15 2009-09-01 Genentech, Inc. Injection vehicle for polymer-based formulations
US7651703B2 (en) * 1999-10-15 2010-01-26 Genentech, Inc. Injection vehicle for polymer-based formulations
DE19956156A1 (de) * 1999-11-23 2001-06-13 Univ Eberhard Karls Verfahren zur Aufbereitung eines Präparates von Thrombozyten und Thrombozytenpräparat
US6871171B1 (en) * 2000-10-19 2005-03-22 Optimata Ltd. System and methods for optimized drug delivery and progression of diseased and normal cells
US6673580B2 (en) 2000-10-27 2004-01-06 Genentech, Inc. Identification and modification of immunodominant epitopes in polypeptides
CZ20032208A3 (cs) * 2001-02-23 2004-01-14 Immunex Corporation Zvýšený výtěžek aktivních proteinů
DE10227606B3 (de) * 2002-06-20 2004-01-22 Bionethos Holding Gmbh Verwendung von Thrombopoietin zur Kultivierung von Hepatozyten
US20040028661A1 (en) * 2002-08-07 2004-02-12 Bartelmez Stephen H. Expansion of cells using thrombopoietin and anti-transforming growth factor-beta
WO2005000891A2 (en) * 2003-06-26 2005-01-06 Merck Patent Gmbh Thrombopoietin proteins with improved properties
WO2005033135A1 (en) * 2003-10-09 2005-04-14 Daewoong Co., Ltd. Process for purifying human thrombopoietin with high content of sialic acid
RU2392314C2 (ru) 2003-12-30 2010-06-20 Аугустинус БАДЕР Способ регенерации ткани
US7879318B2 (en) * 2006-01-23 2011-02-01 Mcw Research Foundation, Inc. Method of reducing the effects of ischemia by administration of a thrombopoietin receptor ligand
US20150031623A1 (en) * 2011-09-29 2015-01-29 Mcw Research Foundation, Inc. Thrombopoietin receptor ligands for neuroprotection
CN102973922B (zh) * 2012-12-18 2016-02-03 华东理工大学 一种融合蛋白的应用
JP6050289B2 (ja) * 2013-07-11 2016-12-21 Ｊｃｒファーマ株式会社 組換え蛋白質高発現細胞株の選択法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3560609B2 (ja) * 1992-11-13 2004-09-02 イミュネックス・コーポレーション Ｅｌｋリガンドと呼ばれる新規なサイトカイン
US5578301A (en) * 1993-12-14 1996-11-26 Sandoz Ltd. Method for using GM-CSF to reduce the acute phase response in a patient being administered IL-6 therapy
GB2285446B (en) * 1994-01-03 1999-07-28 Genentech Inc Thrombopoietin
KR100203824B1 (ko) * 1994-03-31 1999-06-15 스티븐 엠. 오드리 거핵구 성장 및 분화를 자극하기 위한 조성물 및방법
US5593666A (en) * 1994-08-16 1997-01-14 The University Of Tennessee Research Corp. Methods and compositions for treating thrombocytopenia
US6013067A (en) * 1995-06-07 2000-01-11 Zymogenetics, Inc. Methods for increasing hematopoietic cells

Also Published As

Publication number Publication date
DE69712036T2 (de) 2002-11-28
CA2242417A1 (en) 1997-07-31
ATE411039T1 (de) 2008-10-15
JP2000504325A (ja) 2000-04-11
WO1997026907A1 (en) 1997-07-31
EP1201246B1 (de) 2008-10-15
PT876152E (pt) 2002-09-30
EP1201246A2 (de) 2002-05-02
AU711639B2 (en) 1999-10-21
EP1201246A3 (de) 2002-05-08
DK0876152T3 (da) 2002-08-12
AU1533597A (en) 1997-08-20
US5879673A (en) 1999-03-09
DE69739050D1 (de) 2008-11-27
ES2315255T3 (es) 2009-04-01
DK1201246T3 (da) 2009-02-23
ATE216257T1 (de) 2002-05-15
EP0876152A1 (de) 1998-11-11
EP0876152B1 (de) 2002-04-17
ES2175333T3 (es) 2002-11-16

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