DE69707114T2 - 3-aryl-r-carboxyalkyl substituierte glutarimide, ihre herstellung durch ringschluss von 4-aryl-4-cyanoheptandicarbonsäuren und ihre verwendung zur herstellung von 3-aryl-3-hydroxyalkylpiperidinen - Google Patents

3-aryl-r-carboxyalkyl substituierte glutarimide, ihre herstellung durch ringschluss von 4-aryl-4-cyanoheptandicarbonsäuren und ihre verwendung zur herstellung von 3-aryl-3-hydroxyalkylpiperidinen

Info

Publication number
DE69707114T2
DE69707114T2 DE69707114T DE69707114T DE69707114T2 DE 69707114 T2 DE69707114 T2 DE 69707114T2 DE 69707114 T DE69707114 T DE 69707114T DE 69707114 T DE69707114 T DE 69707114T DE 69707114 T2 DE69707114 T2 DE 69707114T2
Authority
DE
Germany
Prior art keywords
aryl
production
ringclassing
hydroxyidalkyl
cyanoheptandicarbonic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69707114T
Other languages
English (en)
Other versions
DE69707114D1 (de
Inventor
Philippe Camus
Marcel Descamps
Joel Radisson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9489959&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69707114(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Publication of DE69707114D1 publication Critical patent/DE69707114D1/de
Application granted granted Critical
Publication of DE69707114T2 publication Critical patent/DE69707114T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86—Oxygen atoms
    • C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69707114T 1996-03-07 1997-03-05 3-aryl-r-carboxyalkyl substituierte glutarimide, ihre herstellung durch ringschluss von 4-aryl-4-cyanoheptandicarbonsäuren und ihre verwendung zur herstellung von 3-aryl-3-hydroxyalkylpiperidinen Expired - Fee Related DE69707114T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9602880A FR2745811B1 (fr) 1996-03-07 1996-03-07 Glutarimide disubstitue procede pour sa preparation, et son utilisation
PCT/FR1997/000388 WO1997032852A1 (fr) 1996-03-07 1997-03-05 Glutarimides 3-aryl-3-carboxyalkyl substitues, leur preparation par cyclisation d'acides dicarboxyliques de la 4-aryl-4-cyanoheptane et leur utilisation pour la preparation de 3-aryl-3-hydroxyalkylpiperidines

Publications (2)

Publication Number Publication Date
DE69707114D1 DE69707114D1 (de) 2001-11-08
DE69707114T2 true DE69707114T2 (de) 2002-06-06

Family

ID=9489959

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69707114T Expired - Fee Related DE69707114T2 (de) 1996-03-07 1997-03-05 3-aryl-r-carboxyalkyl substituierte glutarimide, ihre herstellung durch ringschluss von 4-aryl-4-cyanoheptandicarbonsäuren und ihre verwendung zur herstellung von 3-aryl-3-hydroxyalkylpiperidinen

Country Status (19)

Country Link
US (2) US6008360A (de)
EP (1) EP0888304B1 (de)
JP (1) JP3116051B2 (de)
AR (1) AR006139A1 (de)
AT (1) ATE206399T1 (de)
AU (1) AU2163497A (de)
BR (1) BR9707943C8 (de)
CA (1) CA2244771C (de)
CY (1) CY2276B1 (de)
DE (1) DE69707114T2 (de)
DK (1) DK0888304T3 (de)
ES (1) ES2165594T3 (de)
FR (1) FR2745811B1 (de)
MY (1) MY128754A (de)
NO (1) NO314498B1 (de)
PT (1) PT888304E (de)
TW (1) TW381080B (de)
WO (1) WO1997032852A1 (de)
ZA (1) ZA971999B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2787449B3 (fr) * 1998-12-15 2001-01-12 Sanofi Sa Derives de 3-phenyl-2,6-dioxopiperidin-3-yl propionamide et leur procede de preparation
FR2787448B3 (fr) 1998-12-18 2001-01-12 Sanofi Sa Ester d'alkyle inferieur de l'acide 3-(3,4-dihalogenophenyl) -2,6-dioxopiperidine3-propionique et son mode de preparation
DE10002509A1 (de) 2000-01-21 2001-07-26 Gruenenthal Gmbh Substituierte Glutarimide
WO2002046156A2 (en) 2000-12-06 2002-06-13 Sepracor, Inc. 4,4-disubstituted piperidines for use as dopamine, serotonin and norepinephrine ligands

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3379731A (en) * 1967-06-15 1968-04-23 Ciba Geigy Corp 1, 4-dihydro-1, 4-ethano-isoquinolines
US3985888A (en) * 1969-07-24 1976-10-12 Richardson-Merrell Inc. Methods of inducing sedation using certain spiroalkanone-imides
BE787767A (fr) * 1971-08-21 1973-02-19 Merck Patent Gmbh Procede de preparation d'amides d'acides oxocarboxyliques et d'acides oxocarboxyliques
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
US5625060A (en) * 1991-05-03 1997-04-29 Elf Sanofi Polycyclic amine compounds and their enantiomers, their method of preparation and pharmaceutical compositions on which they are present
FR2696178B1 (fr) * 1992-09-30 1994-12-30 Sanofi Elf Amides basiques quaternaires, procédé pour leur préparation et compositions pharmaceutiques en contenant.
US5583134A (en) * 1992-09-30 1996-12-10 Sanofi 1-azoniabicyclo[2.2.2] octanes and pharmaceutical compositions in which they are present
FR2719311B1 (fr) * 1994-03-18 1998-06-26 Sanofi Sa Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.

Also Published As

Publication number Publication date
DE69707114D1 (de) 2001-11-08
FR2745811B1 (fr) 1998-05-22
ES2165594T3 (es) 2002-03-16
NO984083L (no) 1998-09-04
NO984083D0 (no) 1998-09-04
AU2163497A (en) 1997-09-22
CA2244771A1 (en) 1997-09-12
NO314498B1 (no) 2003-03-31
DK0888304T3 (da) 2002-03-04
BR9707943A (pt) 1999-07-27
CA2244771C (en) 2004-07-13
EP0888304B1 (de) 2001-10-04
JP3116051B2 (ja) 2000-12-11
CY2276B1 (en) 2003-07-04
WO1997032852A1 (fr) 1997-09-12
US6242607B1 (en) 2001-06-05
US6008360A (en) 1999-12-28
TW381080B (en) 2000-02-01
PT888304E (pt) 2002-02-28
JPH11506124A (ja) 1999-06-02
ATE206399T1 (de) 2001-10-15
AR006139A1 (es) 1999-08-11
BR9707943B (pt) 2008-05-20
MY128754A (en) 2007-02-28
BR9707943C8 (pt) 2014-11-18
EP0888304A1 (de) 1999-01-07
FR2745811A1 (fr) 1997-09-12
ZA971999B (en) 1997-09-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-AVENTIS, PARIS, FR

8339 Ceased/non-payment of the annual fee