CY2276B1 - Substituted 3-aryl-3-carboxyalkyl glutaramides method for preparing same by 4-arylo-4-cyanoheptane dicarboxylic acid cyclisation and use thereof for preparing 3-aryl-3-hydroxyalkylpiperidines - Google Patents

Substituted 3-aryl-3-carboxyalkyl glutaramides method for preparing same by 4-arylo-4-cyanoheptane dicarboxylic acid cyclisation and use thereof for preparing 3-aryl-3-hydroxyalkylpiperidines

Info

Publication number
CY2276B1
CY2276B1 CY0200029A CY0200029A CY2276B1 CY 2276 B1 CY2276 B1 CY 2276B1 CY 0200029 A CY0200029 A CY 0200029A CY 0200029 A CY0200029 A CY 0200029A CY 2276 B1 CY2276 B1 CY 2276B1
Authority
CY
Cyprus
Prior art keywords
aryl
preparing
hydroxyalkylpiperidines
glutaramides
cyanoheptane
Prior art date
Application number
CY0200029A
Other languages
English (en)
Inventor
Philippe Camus
Marcel Descamps
Joel Radisson
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9489959&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2276(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of CY2276B1 publication Critical patent/CY2276B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86—Oxygen atoms
    • C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CY0200029A 1996-03-07 2002-05-15 Substituted 3-aryl-3-carboxyalkyl glutaramides method for preparing same by 4-arylo-4-cyanoheptane dicarboxylic acid cyclisation and use thereof for preparing 3-aryl-3-hydroxyalkylpiperidines CY2276B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9602880A FR2745811B1 (fr) 1996-03-07 1996-03-07 Glutarimide disubstitue procede pour sa preparation, et son utilisation

Publications (1)

Publication Number Publication Date
CY2276B1 true CY2276B1 (en) 2003-07-04

Family

ID=9489959

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0200029A CY2276B1 (en) 1996-03-07 2002-05-15 Substituted 3-aryl-3-carboxyalkyl glutaramides method for preparing same by 4-arylo-4-cyanoheptane dicarboxylic acid cyclisation and use thereof for preparing 3-aryl-3-hydroxyalkylpiperidines

Country Status (19)

Country Link
US (2) US6008360A (xx)
EP (1) EP0888304B1 (xx)
JP (1) JP3116051B2 (xx)
AR (1) AR006139A1 (xx)
AT (1) ATE206399T1 (xx)
AU (1) AU2163497A (xx)
BR (1) BR9707943C8 (xx)
CA (1) CA2244771C (xx)
CY (1) CY2276B1 (xx)
DE (1) DE69707114T2 (xx)
DK (1) DK0888304T3 (xx)
ES (1) ES2165594T3 (xx)
FR (1) FR2745811B1 (xx)
MY (1) MY128754A (xx)
NO (1) NO314498B1 (xx)
PT (1) PT888304E (xx)
TW (1) TW381080B (xx)
WO (1) WO1997032852A1 (xx)
ZA (1) ZA971999B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2787449B3 (fr) * 1998-12-15 2001-01-12 Sanofi Sa Derives de 3-phenyl-2,6-dioxopiperidin-3-yl propionamide et leur procede de preparation
FR2787448B3 (fr) 1998-12-18 2001-01-12 Sanofi Sa Ester d'alkyle inferieur de l'acide 3-(3,4-dihalogenophenyl) -2,6-dioxopiperidine3-propionique et son mode de preparation
DE10002509A1 (de) 2000-01-21 2001-07-26 Gruenenthal Gmbh Substituierte Glutarimide
WO2002046156A2 (en) 2000-12-06 2002-06-13 Sepracor, Inc. 4,4-disubstituted piperidines for use as dopamine, serotonin and norepinephrine ligands

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3379731A (en) * 1967-06-15 1968-04-23 Ciba Geigy Corp 1, 4-dihydro-1, 4-ethano-isoquinolines
US3985888A (en) * 1969-07-24 1976-10-12 Richardson-Merrell Inc. Methods of inducing sedation using certain spiroalkanone-imides
BE787767A (fr) * 1971-08-21 1973-02-19 Merck Patent Gmbh Procede de preparation d'amides d'acides oxocarboxyliques et d'acides oxocarboxyliques
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
US5625060A (en) * 1991-05-03 1997-04-29 Elf Sanofi Polycyclic amine compounds and their enantiomers, their method of preparation and pharmaceutical compositions on which they are present
FR2696178B1 (fr) * 1992-09-30 1994-12-30 Sanofi Elf Amides basiques quaternaires, procédé pour leur préparation et compositions pharmaceutiques en contenant.
US5583134A (en) * 1992-09-30 1996-12-10 Sanofi 1-azoniabicyclo[2.2.2] octanes and pharmaceutical compositions in which they are present
FR2719311B1 (fr) * 1994-03-18 1998-06-26 Sanofi Sa Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.

Also Published As

Publication number Publication date
DE69707114D1 (de) 2001-11-08
FR2745811B1 (fr) 1998-05-22
ES2165594T3 (es) 2002-03-16
NO984083L (no) 1998-09-04
NO984083D0 (no) 1998-09-04
AU2163497A (en) 1997-09-22
CA2244771A1 (en) 1997-09-12
NO314498B1 (no) 2003-03-31
DK0888304T3 (da) 2002-03-04
BR9707943A (pt) 1999-07-27
CA2244771C (en) 2004-07-13
DE69707114T2 (de) 2002-06-06
EP0888304B1 (fr) 2001-10-04
JP3116051B2 (ja) 2000-12-11
WO1997032852A1 (fr) 1997-09-12
US6242607B1 (en) 2001-06-05
US6008360A (en) 1999-12-28
TW381080B (en) 2000-02-01
PT888304E (pt) 2002-02-28
JPH11506124A (ja) 1999-06-02
ATE206399T1 (de) 2001-10-15
AR006139A1 (es) 1999-08-11
BR9707943B (pt) 2008-05-20
MY128754A (en) 2007-02-28
BR9707943C8 (pt) 2014-11-18
EP0888304A1 (fr) 1999-01-07
FR2745811A1 (fr) 1997-09-12
ZA971999B (en) 1997-09-09

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