ATE206399T1 - 3-aryl-r-carboxyalkyl substituierte glutarimide, ihre herstellung durch ringschluss von 4-aryl-4- cyanoheptandicarbonsäuren und ihre verwendung zur herstellung von 3-aryl-3-hydroxyalkylpiperidinen - Google Patents

3-aryl-r-carboxyalkyl substituierte glutarimide, ihre herstellung durch ringschluss von 4-aryl-4- cyanoheptandicarbonsäuren und ihre verwendung zur herstellung von 3-aryl-3-hydroxyalkylpiperidinen

Info

Publication number
ATE206399T1
ATE206399T1 AT97914357T AT97914357T ATE206399T1 AT E206399 T1 ATE206399 T1 AT E206399T1 AT 97914357 T AT97914357 T AT 97914357T AT 97914357 T AT97914357 T AT 97914357T AT E206399 T1 ATE206399 T1 AT E206399T1
Authority
AT
Austria
Prior art keywords
aryl
hydroxyalkylpiperidines
cyanoheptanecarbonic
acids
preparation
Prior art date
Application number
AT97914357T
Other languages
English (en)
Inventor
Philippe Camus
Marcel Descamps
Joel Radisson
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9489959&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE206399(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Application granted granted Critical
Publication of ATE206399T1 publication Critical patent/ATE206399T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86Oxygen atoms
    • C07D211/88Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT97914357T 1996-03-07 1997-03-05 3-aryl-r-carboxyalkyl substituierte glutarimide, ihre herstellung durch ringschluss von 4-aryl-4- cyanoheptandicarbonsäuren und ihre verwendung zur herstellung von 3-aryl-3-hydroxyalkylpiperidinen ATE206399T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9602880A FR2745811B1 (fr) 1996-03-07 1996-03-07 Glutarimide disubstitue procede pour sa preparation, et son utilisation
PCT/FR1997/000388 WO1997032852A1 (fr) 1996-03-07 1997-03-05 Glutarimides 3-aryl-3-carboxyalkyl substitues, leur preparation par cyclisation d'acides dicarboxyliques de la 4-aryl-4-cyanoheptane et leur utilisation pour la preparation de 3-aryl-3-hydroxyalkylpiperidines

Publications (1)

Publication Number Publication Date
ATE206399T1 true ATE206399T1 (de) 2001-10-15

Family

ID=9489959

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97914357T ATE206399T1 (de) 1996-03-07 1997-03-05 3-aryl-r-carboxyalkyl substituierte glutarimide, ihre herstellung durch ringschluss von 4-aryl-4- cyanoheptandicarbonsäuren und ihre verwendung zur herstellung von 3-aryl-3-hydroxyalkylpiperidinen

Country Status (19)

Country Link
US (2) US6008360A (de)
EP (1) EP0888304B1 (de)
JP (1) JP3116051B2 (de)
AR (1) AR006139A1 (de)
AT (1) ATE206399T1 (de)
AU (1) AU2163497A (de)
BR (1) BR9707943C8 (de)
CA (1) CA2244771C (de)
CY (1) CY2276B1 (de)
DE (1) DE69707114T2 (de)
DK (1) DK0888304T3 (de)
ES (1) ES2165594T3 (de)
FR (1) FR2745811B1 (de)
MY (1) MY128754A (de)
NO (1) NO314498B1 (de)
PT (1) PT888304E (de)
TW (1) TW381080B (de)
WO (1) WO1997032852A1 (de)
ZA (1) ZA971999B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2787449B3 (fr) 1998-12-15 2001-01-12 Sanofi Sa Derives de 3-phenyl-2,6-dioxopiperidin-3-yl propionamide et leur procede de preparation
FR2787448B3 (fr) * 1998-12-18 2001-01-12 Sanofi Sa Ester d'alkyle inferieur de l'acide 3-(3,4-dihalogenophenyl) -2,6-dioxopiperidine3-propionique et son mode de preparation
RU2152386C1 (ru) * 1999-05-27 2000-07-10 Российский Университет Дружбы Народов Способ получения 2,3,5,6-тетраоксо-4-нитропиридата аммония
DE10002509A1 (de) 2000-01-21 2001-07-26 Gruenenthal Gmbh Substituierte Glutarimide
US6656953B2 (en) 2000-12-06 2003-12-02 Sepracor Inc. 4,4-Disubstituted piperidines, and methods of use thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3379731A (en) * 1967-06-15 1968-04-23 Ciba Geigy Corp 1, 4-dihydro-1, 4-ethano-isoquinolines
US3647797A (en) 1969-07-24 1972-03-07 Richardson Merrell Inc 6-chloro - 2 3-dihydrospiro(naphthalene-(7h) 3'-piperidine)-2' 4 6'-triones
US3985888A (en) * 1969-07-24 1976-10-12 Richardson-Merrell Inc. Methods of inducing sedation using certain spiroalkanone-imides
BE787767A (fr) * 1971-08-21 1973-02-19 Merck Patent Gmbh Procede de preparation d'amides d'acides oxocarboxyliques et d'acides oxocarboxyliques
US5001125A (en) * 1984-03-26 1991-03-19 Janssen Pharmaceutica N.V. Anti-virally active pyridazinamines
US5625060A (en) * 1991-05-03 1997-04-29 Elf Sanofi Polycyclic amine compounds and their enantiomers, their method of preparation and pharmaceutical compositions on which they are present
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
US5583134A (en) * 1992-09-30 1996-12-10 Sanofi 1-azoniabicyclo[2.2.2] octanes and pharmaceutical compositions in which they are present
FR2696178B1 (fr) * 1992-09-30 1994-12-30 Sanofi Elf Amides basiques quaternaires, procédé pour leur préparation et compositions pharmaceutiques en contenant.
FR2719311B1 (fr) * 1994-03-18 1998-06-26 Sanofi Sa Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.

Also Published As

Publication number Publication date
ES2165594T3 (es) 2002-03-16
NO314498B1 (no) 2003-03-31
FR2745811B1 (fr) 1998-05-22
JP3116051B2 (ja) 2000-12-11
CA2244771C (en) 2004-07-13
US6008360A (en) 1999-12-28
CA2244771A1 (en) 1997-09-12
NO984083D0 (no) 1998-09-04
BR9707943B (pt) 2008-05-20
JPH11506124A (ja) 1999-06-02
PT888304E (pt) 2002-02-28
AU2163497A (en) 1997-09-22
FR2745811A1 (fr) 1997-09-12
BR9707943A (pt) 1999-07-27
DK0888304T3 (da) 2002-03-04
TW381080B (en) 2000-02-01
NO984083L (no) 1998-09-04
ZA971999B (en) 1997-09-09
CY2276B1 (en) 2003-07-04
DE69707114T2 (de) 2002-06-06
EP0888304A1 (de) 1999-01-07
BR9707943C8 (pt) 2014-11-18
DE69707114D1 (de) 2001-11-08
MY128754A (en) 2007-02-28
US6242607B1 (en) 2001-06-05
EP0888304B1 (de) 2001-10-04
AR006139A1 (es) 1999-08-11
WO1997032852A1 (fr) 1997-09-12

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