DE69704554T2 - Konfokales mikroskop - Google Patents

Konfokales mikroskop

Info

Publication number
DE69704554T2
DE69704554T2 DE69704554T DE69704554T DE69704554T2 DE 69704554 T2 DE69704554 T2 DE 69704554T2 DE 69704554 T DE69704554 T DE 69704554T DE 69704554 T DE69704554 T DE 69704554T DE 69704554 T2 DE69704554 T2 DE 69704554T2
Authority
DE
Germany
Prior art keywords
confocal
specimen
pct
light
encoded
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69704554T
Other languages
English (en)
Other versions
DE69704554D1 (de
Inventor
Tony Wilson
Mark Andrew Aquilla Neil
Rimvydas Juskaitis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford University Innovation Ltd
Original Assignee
Oxford University Innovation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford University Innovation Ltd filed Critical Oxford University Innovation Ltd
Application granted granted Critical
Publication of DE69704554D1 publication Critical patent/DE69704554D1/de
Publication of DE69704554T2 publication Critical patent/DE69704554T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036—Scanning details, e.g. scanning stages
    • G02B21/004—Scanning details, e.g. scanning stages fixed arrays, e.g. switchable aperture arrays
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/008—Details of detection or image processing, including general computer control
    • G02B21/0084—Details of detection or image processing, including general computer control time-scale detection, e.g. strobed, ultra-fast, heterodyne detection

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Engineering & Computer Science (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Dental Preparations (AREA)
DE69704554T 1996-02-22 1997-02-21 Konfokales mikroskop Expired - Lifetime DE69704554T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9603788.2A GB9603788D0 (en) 1996-02-22 1996-02-22 Confocal microscope
PCT/GB1997/000490 WO1997031282A1 (en) 1996-02-22 1997-02-21 Confocal microscope

Publications (2)

Publication Number Publication Date
DE69704554D1 DE69704554D1 (de) 2001-05-17
DE69704554T2 true DE69704554T2 (de) 2001-08-09

Family

ID=10789235

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69704554T Expired - Lifetime DE69704554T2 (de) 1996-02-22 1997-02-21 Konfokales mikroskop

Country Status (10)

Country Link
US (1) US6144489A (de)
EP (1) EP0882247B1 (de)
JP (1) JP4049393B2 (de)
AT (1) ATE200585T1 (de)
AU (1) AU1885997A (de)
CA (1) CA2246698C (de)
DE (1) DE69704554T2 (de)
ES (1) ES2156364T3 (de)
GB (1) GB9603788D0 (de)
WO (1) WO1997031282A1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8643946B2 (en) 2006-06-16 2014-02-04 Carl Zeiss Microscopy Gmbh Autofocus device for microscopy
DE102014004249A1 (de) * 2014-03-24 2015-09-24 Carl Zeiss Microscopy Gmbh Konfokales Mikroskop mit Aperturkorrelation

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE236412T1 (de) 1997-10-22 2003-04-15 Max Planck Gesellschaft Programmierbares räumlich lichtmoduliertes mikroskop und mikroskopieverfahren
AU9617598A (en) * 1997-10-29 1999-05-17 Calum E. Macaulay Apparatus and methods relating to spatially light modulated microscopy
ATE272224T1 (de) * 1997-11-17 2004-08-15 Max Planck Gesellschaft Konfokales spektroskopiesystem und -verfahren
GB9807832D0 (en) 1998-04-09 1998-06-10 Isis Innovation Imaging apparatus
JP3670839B2 (ja) 1998-05-18 2005-07-13 オリンパス株式会社 共焦点顕微鏡
DE19824460A1 (de) * 1998-05-30 1999-12-02 Zeiss Carl Jena Gmbh Anordnung und Verfahren zur mikroskopischen Erzeugung von Objektbildern
GB9901365D0 (en) 1999-01-22 1999-03-10 Isis Innovations Ltd Confocal microscopy apparatus and method
DE19908883A1 (de) 1999-03-02 2000-09-07 Rainer Heintzmann Verfahren zur Erhöhung der Auflösung optischer Abbildung
US6426835B1 (en) 1999-03-23 2002-07-30 Olympus Optical Co., Ltd. Confocal microscope
DE19960583A1 (de) * 1999-12-15 2001-07-05 Evotec Biosystems Ag Verfahren und Vorrichtung zur Mikroskopie
TWI254141B (en) 2000-03-06 2006-05-01 Olympus Optical Co Pattern forming member applied to sectioning image observation apparatus and sectioning image observation apparatus using them
JPWO2002091090A1 (ja) * 2001-04-27 2004-08-26 シチズン時計株式会社 自動旋盤及びその制御方法及びその制御装置
JP3634343B2 (ja) * 2001-09-03 2005-03-30 株式会社林創研 デジタル制御走査方法および装置
US6885492B2 (en) 2001-11-08 2005-04-26 Imaginative Optics, Inc. Spatial light modulator apparatus
US6844927B2 (en) * 2002-11-27 2005-01-18 Kla-Tencor Technologies Corporation Apparatus and methods for removing optical abberations during an optical inspection
DE602004024464D1 (de) 2003-07-04 2010-01-14 Vincent Lauer Bildgebungsvorrichtung für konfokale Mikroskopie mit Bildsubstraktion
JP4425098B2 (ja) * 2004-09-06 2010-03-03 浜松ホトニクス株式会社 蛍光顕微鏡および蛍光相関分光解析装置
EP1869615B1 (de) 2004-11-16 2010-03-03 Illumina, Inc. Verfahren und vorrichtung zum lesen von kodierten mikrokugeln
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
EP2016456A4 (de) * 2006-04-20 2010-08-25 Xceed Imaging Ltd Durchweg optisches system und verfahren zur bereitstellung einer vergrösserten schärfentiefe bei der abbildung
US7460248B2 (en) * 2006-05-15 2008-12-02 Carestream Health, Inc. Tissue imaging system
WO2008081729A1 (ja) * 2006-12-22 2008-07-10 Nikon Corporation レーザ走査共焦点顕微鏡
US8228561B2 (en) * 2007-03-30 2012-07-24 Xerox Corporation Method and system for selective bitmap edge smoothing
US8368959B2 (en) 2009-05-18 2013-02-05 Xerox Corporation Method and system for selective smoothing of halftoned objects using bitmap encoding
WO2011136857A2 (en) * 2010-01-06 2011-11-03 Trustees Of Boston University Correlation confocal microscope
DE102011013613A1 (de) * 2010-10-01 2012-04-05 Carl Zeiss Microimaging Gmbh Mikroskop und Mikroskopierverfahren
US8797601B2 (en) 2012-03-22 2014-08-05 Xerox Corporation Method and system for preserving image quality in an economy print mode
DE102012208869A1 (de) 2012-05-25 2013-11-28 Carl Zeiss Microscopy Gmbh Lichtrastermikroskop und Mikroskopierverfahren
DE102012007045B4 (de) * 2012-04-05 2023-03-16 Carl Zeiss Microscopy Gmbh Vorrichtung und Verfahren zur Mikroskopie
DE102013208872B4 (de) 2013-05-14 2023-08-17 Carl Zeiss Microscopy Gmbh Verfahren zur Erzeugung eines Bildes einer Probe
HU231246B1 (hu) 2015-08-31 2022-05-28 3Dhistech Kft Konfokális elvû tárgylemez szkenner
DE102017105719A1 (de) 2017-03-16 2018-09-20 Carl Zeiss Microscopy Gmbh Multi-Pinhole-Lichtrastermikroskop und -mikroskopieverfahren
DE102018210606A1 (de) 2018-06-28 2020-01-02 Carl Zeiss Microscopy Gmbh Mikroskopisches Abbildungsverfahren unter Verwendung eines Korrekturfaktors
JP2023544485A (ja) 2020-08-25 2023-10-24 オーロックス リミテッド 顕微鏡

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4806004A (en) * 1987-07-10 1989-02-21 California Institute Of Technology Scanning microscopy
US5235457A (en) * 1987-09-24 1993-08-10 Washington University Kit for converting a standard microscope into a single aperture confocal scanning epi-illumination microscope
ATE120559T1 (de) * 1987-09-24 1995-04-15 Univ Washington Konzept und umwandlungssatz eines standardmikroskops in ein mikroskop mit gemeinsamem brennpunkt und epi-beleuchtung mit einzelöffnung.
GB9014570D0 (en) * 1990-06-29 1990-08-22 Dixon Arthur E Method for transmitted-light and reflected-light imaging
DE4023292A1 (de) * 1990-07-21 1992-01-23 Leica Lasertechnik Anordnung zur simultanen konfokalen bilderzeugung
ATE137588T1 (de) * 1990-11-10 1996-05-15 Grosskopf Rudolf Dr Ing Optische abtastvorrichtung mit konfokalem strahlengang, in der lichtquellen- und detektormatrix verwendet werden
US5386317A (en) * 1992-05-13 1995-01-31 Prometrix Corporation Method and apparatus for imaging dense linewidth features using an optical microscope
US5587832A (en) * 1993-10-20 1996-12-24 Biophysica Technologies, Inc. Spatially light modulated confocal microscope and method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8643946B2 (en) 2006-06-16 2014-02-04 Carl Zeiss Microscopy Gmbh Autofocus device for microscopy
DE102014004249A1 (de) * 2014-03-24 2015-09-24 Carl Zeiss Microscopy Gmbh Konfokales Mikroskop mit Aperturkorrelation

Also Published As

Publication number Publication date
WO1997031282A1 (en) 1997-08-28
ATE200585T1 (de) 2001-04-15
ES2156364T3 (es) 2001-06-16
GB9603788D0 (en) 1996-04-24
EP0882247A1 (de) 1998-12-09
CA2246698A1 (en) 1997-08-28
CA2246698C (en) 2005-07-26
JP4049393B2 (ja) 2008-02-20
DE69704554D1 (de) 2001-05-17
US6144489A (en) 2000-11-07
EP0882247B1 (de) 2001-04-11
AU1885997A (en) 1997-09-10
JP2000504858A (ja) 2000-04-18

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