DE69636739D1 - Verfahren zur rückfaltung von menschlichem activin a - Google Patents
Verfahren zur rückfaltung von menschlichem activin aInfo
- Publication number
- DE69636739D1 DE69636739D1 DE69636739T DE69636739T DE69636739D1 DE 69636739 D1 DE69636739 D1 DE 69636739D1 DE 69636739 T DE69636739 T DE 69636739T DE 69636739 T DE69636739 T DE 69636739T DE 69636739 D1 DE69636739 D1 DE 69636739D1
- Authority
- DE
- Germany
- Prior art keywords
- reconstruction
- human activin
- activin
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP33307095 | 1995-12-21 | ||
JP33307095 | 1995-12-21 | ||
PCT/JP1996/003700 WO1997023638A1 (fr) | 1995-12-21 | 1996-12-19 | Procede pour replier l'activine a humaine |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69636739D1 true DE69636739D1 (de) | 2007-01-11 |
DE69636739T2 DE69636739T2 (de) | 2007-10-18 |
Family
ID=18261933
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69636739T Expired - Lifetime DE69636739T2 (de) | 1995-12-21 | 1996-12-19 | Verfahren zur rückfaltung von menschlichem activin a |
Country Status (5)
Country | Link |
---|---|
US (1) | US6084076A (de) |
EP (1) | EP0943690B1 (de) |
JP (1) | JP4019432B2 (de) |
DE (1) | DE69636739T2 (de) |
WO (1) | WO1997023638A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4055248B2 (ja) * | 1998-05-25 | 2008-03-05 | 味の素株式会社 | 精製ヒトアクチビン及びその製造方法 |
US7442370B2 (en) * | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
US7276580B2 (en) * | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
GB0220199D0 (en) * | 2002-08-30 | 2002-10-09 | Univ Utrecht | Mutant protein and refolding method |
JP4571776B2 (ja) * | 2002-11-05 | 2010-10-27 | Jx日鉱日石エネルギー株式会社 | 潤滑油組成物 |
JPWO2004056872A1 (ja) * | 2002-12-20 | 2006-04-20 | 三菱ウェルファーマ株式会社 | タンパク質のチオール基を保護する方法 |
EP1897552B1 (de) | 2003-04-18 | 2009-06-17 | Biogen Idec MA Inc. | Polymerkonjugiertes glycosiliertes Neublastin |
AU2005277227B2 (en) | 2004-08-19 | 2011-10-06 | Biogen Ma Inc. | Refolding transforming growth factor beta family proteins |
MX2007002029A (es) * | 2004-08-19 | 2007-03-28 | Biogen Idec Inc | Variantes de neublastina. |
TWI501774B (zh) * | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | 神經性病症之治療 |
US20100056440A1 (en) * | 2006-03-01 | 2010-03-04 | Biogen Idec Ma Inc. | Compositions and methods for administering gdnf ligand family proteins |
GB0604964D0 (en) | 2006-03-11 | 2006-04-19 | Renovo Ltd | Protein folding |
GB0604966D0 (en) | 2006-03-11 | 2006-04-19 | Renovo Ltd | Medicaments and proteins |
GB0604938D0 (en) | 2006-03-11 | 2006-04-19 | Renovo Ltd | Proteins, nucleic acids and medicaments |
CA2685686A1 (en) | 2007-05-01 | 2008-11-13 | Biogen Idec Ma Inc. | Neublastin polypeptides for use increasing vascularization in a tissue |
WO2009020964A2 (en) * | 2007-08-08 | 2009-02-12 | Biogen Idec Ma Inc. | Anti-neublastin antibodies and uses thereof |
JP2016183118A (ja) * | 2015-03-25 | 2016-10-20 | 東ソー株式会社 | 増殖因子前駆体のリフォールディング方法 |
JP7325722B2 (ja) | 2018-03-22 | 2023-08-15 | 味の素株式会社 | 組換えアクチビンa前駆体タンパク質 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4798885A (en) * | 1986-02-07 | 1989-01-17 | Genentech, Inc. | Compositions of hormonally active human and porcine inhibin containing an α chain and 62 chain |
ZA867569B (en) * | 1985-10-03 | 1988-06-29 | Genentech Inc | Nucleic acid encoding the alpha or beta chains of inhibin and method for synthesizing polypeptides using such nucleic acid |
DE3835350A1 (de) * | 1988-10-17 | 1990-04-19 | Boehringer Mannheim Gmbh | Aktivierung von gentechnologisch hergestellten, in prokaryonten exprimierten antikoerpern |
GB8927546D0 (en) * | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
US5144006A (en) * | 1991-06-13 | 1992-09-01 | The Rockefeller University | Oxidative folding of peptide and protein substrates using hydrocarbon sulfoxides |
US5658876A (en) * | 1994-04-28 | 1997-08-19 | The General Hospital Corporation | Activin antagonists as novel contraceptives |
TW517059B (en) * | 1994-07-25 | 2003-01-11 | Ciba Geigy Ag | New process for the production of biologically active protein |
TW440566B (en) * | 1994-07-25 | 2001-06-16 | Novartis Ag | Novel process for the production of biologically active dimeric protein |
-
1996
- 1996-12-19 EP EP96942573A patent/EP0943690B1/de not_active Expired - Lifetime
- 1996-12-19 WO PCT/JP1996/003700 patent/WO1997023638A1/ja active IP Right Grant
- 1996-12-19 DE DE69636739T patent/DE69636739T2/de not_active Expired - Lifetime
- 1996-12-19 JP JP52349797A patent/JP4019432B2/ja not_active Expired - Lifetime
- 1996-12-19 US US09/091,265 patent/US6084076A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0943690A4 (de) | 1999-09-22 |
JP4019432B2 (ja) | 2007-12-12 |
DE69636739T2 (de) | 2007-10-18 |
WO1997023638A1 (fr) | 1997-07-03 |
EP0943690A1 (de) | 1999-09-22 |
US6084076A (en) | 2000-07-04 |
EP0943690B1 (de) | 2006-11-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |