DE69633925D1 - Verfahren zu herstellung einer granulären zubereitung - Google Patents

Verfahren zu herstellung einer granulären zubereitung

Info

Publication number
DE69633925D1
DE69633925D1 DE69633925T DE69633925T DE69633925D1 DE 69633925 D1 DE69633925 D1 DE 69633925D1 DE 69633925 T DE69633925 T DE 69633925T DE 69633925 T DE69633925 T DE 69633925T DE 69633925 D1 DE69633925 D1 DE 69633925D1
Authority
DE
Germany
Prior art keywords
powdered
granular preparation
medicine
producing
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69633925T
Other languages
English (en)
Other versions
DE69633925T2 (de
Inventor
Hiroaki Nakagami
Tadanao Yamao
Ario Funada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69633925D1 publication Critical patent/DE69633925D1/de
Publication of DE69633925T2 publication Critical patent/DE69633925T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
DE69633925T 1995-07-21 1996-07-19 Verfahren zur Herstellung einer granulären Zubereitung Expired - Lifetime DE69633925T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP20672695 1995-07-21
JP20672695 1995-07-21
PCT/JP1996/002028 WO1997003656A1 (fr) 1995-07-21 1996-07-19 Preparation granulaire et son procede de production

Publications (2)

Publication Number Publication Date
DE69633925D1 true DE69633925D1 (de) 2004-12-30
DE69633925T2 DE69633925T2 (de) 2005-11-24

Family

ID=16528097

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69633925T Expired - Lifetime DE69633925T2 (de) 1995-07-21 1996-07-19 Verfahren zur Herstellung einer granulären Zubereitung

Country Status (14)

Country Link
US (1) US6217910B1 (de)
EP (1) EP0841062B1 (de)
KR (1) KR100417746B1 (de)
CN (1) CN1089235C (de)
AT (1) ATE283038T1 (de)
AU (1) AU700961B2 (de)
DE (1) DE69633925T2 (de)
EA (1) EA000467B1 (de)
ES (1) ES2233971T3 (de)
HK (1) HK1008491A1 (de)
NO (1) NO324286B1 (de)
PT (1) PT841062E (de)
TW (1) TW503114B (de)
WO (1) WO1997003656A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6242019B1 (en) 1997-08-14 2001-06-05 Warner-Lambert Company Taste modified hard confectionery compositions containing functional ingredients
AU4802699A (en) * 1998-07-31 2000-02-21 Otsuka Pharmaceutical Co., Ltd. Pharmaceutical composition having improved taste
RU2270695C2 (ru) * 1999-03-17 2006-02-27 Дайити Фармасьютикал Ко., Лтд. Фармацевтическая композиция
JP4310605B2 (ja) * 2001-05-25 2009-08-12 大塚製薬株式会社 医薬用組成物
JP4974419B2 (ja) * 2001-06-12 2012-07-11 東和薬品株式会社 薬物含有徐放性顆粒およびそれを含む錠剤
SE0200154D0 (sv) * 2002-01-21 2002-01-21 Galenica Ab New process
EP1484056B1 (de) * 2002-02-21 2013-08-14 Otsuka Pharmaceutical Co., Ltd. Zubereitungen mit verzögerter freisetzung und verfahren für ihre herstellung
CN1812793A (zh) 2003-06-27 2006-08-02 大塚制药株式会社 药物持续释放颗粒及其制备方法
GB0322848D0 (en) * 2003-09-30 2003-10-29 Alpharma Ltd Tetracycline controlled release pharmaceutical dosage form
KR101168189B1 (ko) * 2003-10-29 2012-07-25 시오노기세이야쿠가부시키가이샤 불쾌미를 개선한 피복 제제의 제조 방법
US20060241144A1 (en) * 2005-04-20 2006-10-26 Albert Cha Method for treating apathy syndrome
PT2001445E (pt) 2006-03-16 2014-10-24 Euro Celtique Sa Esferoides farmacêuticos
JP2009073774A (ja) * 2007-09-21 2009-04-09 Takada Seiyaku Kk レボフロキサシン粒状製剤の製造方法及び該方法で得られた粒状製剤
EP2198859A1 (de) 2008-12-17 2010-06-23 Losan Pharma GmbH Schmelzbeschichtete pharmazeutische Zusammensetzung mit Freisetzung
US20220370368A1 (en) 2019-10-31 2022-11-24 Hermes Pharma Gmbh Oral pharmaceutical composition comprising a melt-agglomerated active ingredient core

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58214333A (ja) 1982-06-04 1983-12-13 Dai Ichi Seiyaku Co Ltd 粒状物
IT1200217B (it) 1986-09-30 1989-01-05 Valducci Roberto Membrana per uso farmaceutico ed industriale
US5169645A (en) * 1989-10-31 1992-12-08 Duquesne University Of The Holy Ghost Directly compressible granules having improved flow properties
JP3130058B2 (ja) 1991-02-15 2001-01-31 第一製薬株式会社 マスクされた粒状物
ES2194863T3 (es) 1992-11-30 2003-12-01 Kv Pharm Co Materiales farmaceuticos con enmascarado de sabor.
IL139728A (en) * 1995-01-09 2003-06-24 Penwest Pharmaceuticals Compan Aqueous slurry composition containing microcrystalline cellulose for preparing a pharmaceutical excipient

Also Published As

Publication number Publication date
CN1089235C (zh) 2002-08-21
ATE283038T1 (de) 2004-12-15
KR19990035794A (ko) 1999-05-25
NO324286B1 (no) 2007-09-17
PT841062E (pt) 2005-03-31
NO980245D0 (no) 1998-01-20
AU700961B2 (en) 1999-01-14
EP0841062A4 (de) 2000-07-19
EP0841062A1 (de) 1998-05-13
DE69633925T2 (de) 2005-11-24
EA000467B1 (ru) 1999-08-26
EA199800145A1 (ru) 1998-08-27
WO1997003656A1 (fr) 1997-02-06
ES2233971T3 (es) 2005-06-16
KR100417746B1 (ko) 2004-05-31
NO980245L (no) 1998-03-23
TW503114B (en) 2002-09-21
AU6470796A (en) 1997-02-18
HK1008491A1 (en) 1999-07-16
CN1207674A (zh) 1999-02-10
US6217910B1 (en) 2001-04-17
EP0841062B1 (de) 2004-11-24

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