DE69632571T2 - Tumorhemmende zusammensetzung enthaltend ascorbinsäure und metallkomplexe von (na)phthalocyaninen - Google Patents

Tumorhemmende zusammensetzung enthaltend ascorbinsäure und metallkomplexe von (na)phthalocyaninen Download PDF

Info

Publication number
DE69632571T2
DE69632571T2 DE69632571T DE69632571T DE69632571T2 DE 69632571 T2 DE69632571 T2 DE 69632571T2 DE 69632571 T DE69632571 T DE 69632571T DE 69632571 T DE69632571 T DE 69632571T DE 69632571 T2 DE69632571 T2 DE 69632571T2
Authority
DE
Germany
Prior art keywords
ascorbic acid
tumor
von
phthalocyanines
mice
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69632571T
Other languages
German (de)
English (en)
Other versions
DE69632571D1 (de
Inventor
Mark Efimovich Volpin
Georgy Nikolaevich Vorozhtsov
Galina Konstantinovna Gerasimova
Olga Stepanovna Zhukova
Natalya Ivanovna Kazachkina
Oleg Leonidovich Kalia
Nadezhda Jurievna Krainova
Ilia Yakovlevich Levitin
Jury Mikhailovich Luzhkov
Evgeny Antonovich Lukiyanets
Galina Nikolaevna Novodarova
Elena Mikhailovna Treschalina
Anatoly Borisovich Syrkin
Valery Ivanovich Chissov
Raisa Ivanovna Yakubovskaya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GOSUDARSTVENNYJ NAUCNYJ CENTR ROSSIJSKOJ FEDERACII "NIOPIK" (GNTS RF "NIOPIK") MOSKAU/MOSCOW
INSTITUT ELEMENTOORGANICESKICH SOEDINENIJ ROSSIJSKOJ AKADEMII NAUK (INEOS RAN) MOSKAU/MOSCOW
Moskovskij Naucno-Issledovatel'skij Onkologiceskij Institut Im Pagertsena (mnioi Im Pa Gertsena) Moskau/moscow
ONKOLOGICESKIJ NAUCNYJ CENTR ROSSIJSKOJ AKADEMII MEDICINSKICH NAUK (ONTS RAMN)
G NAUCNYJ CENTR ROSSIJSKOJ FED
Gosudarstvennyj Naucnyj Centr Rossijskoj Federacii "niopik" (gnts Rf "niopik")
INST ELEMENTOORGANICHESKIKH SO
Institut Elementoorganiceskich Soedinenij Rossijskoj Akademii Nauk (ineos Ran)
MO NI SKIJ ONKOLOGICESKIJ I IM
Moskovskij Naucno-Issledovatel'skij Onkologiceskij Institut Im Pagertsena (mnioi Im Pa Gertsena)
ONKOLOGICESKIJ NAUCNYJ CENTR R
Onkologiceskij Naucnyj Centr Rossijskoj Akademii Medicinskich Nauk (Onts Ramn)
Original Assignee
GOSUDARSTVENNYJ NAUCNYJ CENTR ROSSIJSKOJ FEDERACII "NIOPIK" (GNTS RF "NIOPIK") MOSKAU/MOSCOW
INSTITUT ELEMENTOORGANICESKICH SOEDINENIJ ROSSIJSKOJ AKADEMII NAUK (INEOS RAN) MOSKAU/MOSCOW
Moskovskij Naucno-Issledovatel'skij Onkologiceskij Institut Im Pagertsena (mnioi Im Pa Gertsena) Moskau/moscow
ONKOLOGICESKIJ NAUCNYJ CENTR ROSSIJSKOJ AKADEMII MEDICINSKICH NAUK (ONTS RAMN)
G NAUCNYJ CENTR ROSSIJSKOJ FED
Gosudarstvennyj Naucnyj Centr Rossijskoj Federacii "niopik" (gnts Rf "niopik")
INST ELEMENTOORGANICHESKIKH SO
Institut Elementoorganiceskich Soedinenij Rossijskoj Akademii Nauk (ineos Ran)
MO NI SKIJ ONKOLOGICESKIJ I IM
Moskovskij Naucno-Issledovatel'skij Onkologiceskij Institut Im Pagertsena (mnioi Im Pa Gertsena)
ONKOLOGICESKIJ NAUCNYJ CENTR R
Onkologiceskij Naucnyj Centr Rossijskoj Akademii Medicinskich Nauk (Onts Ramn)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU95112240A external-priority patent/RU2106146C1/ru
Application filed by GOSUDARSTVENNYJ NAUCNYJ CENTR ROSSIJSKOJ FEDERACII "NIOPIK" (GNTS RF "NIOPIK") MOSKAU/MOSCOW, INSTITUT ELEMENTOORGANICESKICH SOEDINENIJ ROSSIJSKOJ AKADEMII NAUK (INEOS RAN) MOSKAU/MOSCOW, Moskovskij Naucno-Issledovatel'skij Onkologiceskij Institut Im Pagertsena (mnioi Im Pa Gertsena) Moskau/moscow, ONKOLOGICESKIJ NAUCNYJ CENTR ROSSIJSKOJ AKADEMII MEDICINSKICH NAUK (ONTS RAMN), G NAUCNYJ CENTR ROSSIJSKOJ FED, Gosudarstvennyj Naucnyj Centr Rossijskoj Federacii "niopik" (gnts Rf "niopik"), INST ELEMENTOORGANICHESKIKH SO, Institut Elementoorganiceskich Soedinenij Rossijskoj Akademii Nauk (ineos Ran), MO NI SKIJ ONKOLOGICESKIJ I IM, Moskovskij Naucno-Issledovatel'skij Onkologiceskij Institut Im Pagertsena (mnioi Im Pa Gertsena), ONKOLOGICESKIJ NAUCNYJ CENTR R, Onkologiceskij Naucnyj Centr Rossijskoj Akademii Medicinskich Nauk (Onts Ramn) filed Critical GOSUDARSTVENNYJ NAUCNYJ CENTR ROSSIJSKOJ FEDERACII "NIOPIK" (GNTS RF "NIOPIK") MOSKAU/MOSCOW
Publication of DE69632571D1 publication Critical patent/DE69632571D1/de
Application granted granted Critical
Publication of DE69632571T2 publication Critical patent/DE69632571T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69632571T 1995-07-17 1996-03-18 Tumorhemmende zusammensetzung enthaltend ascorbinsäure und metallkomplexe von (na)phthalocyaninen Expired - Lifetime DE69632571T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU95112240 1995-07-17
RU95112240A RU2106146C1 (ru) 1995-07-17 1995-07-17 Средство для подавления опухолевого роста
PCT/RU1996/000060 WO1997003666A1 (fr) 1995-07-17 1996-03-18 Agent d'inhibition de croissance tumorale

Publications (2)

Publication Number Publication Date
DE69632571D1 DE69632571D1 (de) 2004-07-01
DE69632571T2 true DE69632571T2 (de) 2005-08-18

Family

ID=34806288

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69632571T Expired - Lifetime DE69632571T2 (de) 1995-07-17 1996-03-18 Tumorhemmende zusammensetzung enthaltend ascorbinsäure und metallkomplexe von (na)phthalocyaninen

Country Status (2)

Country Link
JP (1) JP3672928B2 (ja)
DE (1) DE69632571T2 (ja)

Also Published As

Publication number Publication date
DE69632571D1 (de) 2004-07-01
JPH10508039A (ja) 1998-08-04
JP3672928B2 (ja) 2005-07-20

Similar Documents

Publication Publication Date Title
DE3120460C2 (ja)
DE69813898T2 (de) Substituierte porphyrinen
DE60317711T2 (de) Kationische porphyrin-derivate als antibakterielle mittel
DE69928655T2 (de) Substituierte porphyrine
DE69923322T2 (de) Verwendung von propionyl-l-carnitin und acetyl-l-carnitin zur herstellung von arzneimittel mit antikrebs wirkung
DD292263A5 (de) Verfahren zur herstellung neuer assoziate der hyaluronsaeure
DE19936428A1 (de) Eisenionen enthaltendes Bakterizid
EP0786253B1 (en) Antitumor composition comprising ascorbic acid and metal complexes of (na)phthalocyanines
DE69932939T2 (de) Fulvinsäure und dessen verwendung zur behandlung von diversen krankheitszuständen
DE69006654T2 (de) Einen Zink-Komplex enthaltende Arzneimittel.
DE69833333T2 (de) Pharmazeutische zusammensetzung enthaltend geweihextrakte von cervus nippon mit wachstumsstimulierender aktivität auf hematopoietische stammzellen und megakaryozyten
DE68902581T2 (de) Pharmazeutische zusammensetzungen mit krebshemmender wirkung.
DE69727399T2 (de) Verwendung von neutralen Gallium Chelaten mit 3-Hydroxy-4-Pyrone Verbindungen zur Behandlung von Krankheiten die verbessert werden Können durch die Hemmung der Hyperproliferation von Keratinocyten
DE69427130T2 (de) Ssi tyrphostine und pharmazeutische zusammensetzungen
DE69426865T2 (de) Pharmazeutische Zusammensetzungen enthaltend Pyryliumverbindungen, Pyryliumsalze und Verfahren zur Herstellung eines Medikaments enthaltend diese Verbindungen
DD217522A5 (de) Verfahren zur herstellung einer medizinischen zubereitung zur behandlung von krebs
EP0313942A1 (de) Verwendung von Fluoronderivaten und Mittel zur Kontrastierung von bösartigen Neubildungen bei deren Diagnostik
DE69632571T2 (de) Tumorhemmende zusammensetzung enthaltend ascorbinsäure und metallkomplexe von (na)phthalocyaninen
EP2047855B1 (de) Antitumorale, antibakterielle und antivirale pharmazeutische zusammensetzung (varianten)
DE68907392T2 (de) Dysmnesie modifizierende Arzneimittel.
DE69706241T2 (de) Pharmazeutische Zusammensetzung zur Behandlung der Leukämie enthaltend 9-cis-Retinoinsäure-alpha-Tocopherolester
DE3787971T2 (de) Aktives prinzip, isoliert aus haigeweben.
DE60024969T2 (de) 2-methyl-3-butenyl-1-pyrophosphorsäuresalze und mittel zur behandlung von lymphozyten
WO2007030848A2 (de) Nichtfluoreszierende chlorophyllkataboliten
Lialiaris et al. Comparative study on cytogenetic effects by diplatinum complexes of the ligands of naphthazarine and squaric acid in human lymphocytes.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition