DE69626986D1 - Endothelinrezeptorantagonist - Google Patents

Endothelinrezeptorantagonist

Info

Publication number
DE69626986D1
DE69626986D1 DE69626986T DE69626986T DE69626986D1 DE 69626986 D1 DE69626986 D1 DE 69626986D1 DE 69626986 T DE69626986 T DE 69626986T DE 69626986 T DE69626986 T DE 69626986T DE 69626986 D1 DE69626986 D1 DE 69626986D1
Authority
DE
Germany
Prior art keywords
endothelin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69626986T
Other languages
English (en)
Other versions
DE69626986T2 (de
Inventor
Duncan Elliott
Ignacio Luengo
Jia-Ning Xiang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
GlaxoSmithKline LLC
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline LLC, SmithKline Beecham Corp filed Critical GlaxoSmithKline LLC
Publication of DE69626986D1 publication Critical patent/DE69626986D1/de
Application granted granted Critical
Publication of DE69626986T2 publication Critical patent/DE69626986T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69626986T 1995-08-02 1996-08-02 Endothelinrezeptorantagonist Expired - Fee Related DE69626986T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US179495P 1995-08-02 1995-08-02
US601794 1995-08-02
US1100996P 1996-02-01 1996-02-01
US601109 1996-02-01
PCT/US1996/012584 WO1997004774A1 (en) 1995-08-02 1996-08-02 Endothelin receptor antagonists

Publications (2)

Publication Number Publication Date
DE69626986D1 true DE69626986D1 (de) 2003-04-30
DE69626986T2 DE69626986T2 (de) 2004-02-05

Family

ID=26669476

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69626986T Expired - Fee Related DE69626986T2 (de) 1995-08-02 1996-08-02 Endothelinrezeptorantagonist

Country Status (5)

Country Link
EP (1) EP0841926B1 (de)
JP (1) JPH11513022A (de)
DE (1) DE69626986T2 (de)
ES (1) ES2195002T3 (de)
WO (1) WO1997004774A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997028160A1 (en) * 1996-02-01 1997-08-07 Smithkline Beecham Corporation Endothelin receptor antagonists
AU2389100A (en) 1998-12-23 2000-07-12 Glaxo Group Limited Assays for ligands for nuclear receptors
EP1454625A1 (de) * 2003-03-06 2004-09-08 Speedel Development AG Pyridylsulfonamidyl-pyrimidine zur Behandlung von diabetischen nephropathien
RU2007106868A (ru) 2004-08-23 2008-09-27 Вайет (Us) Оксазол-нафтиловые кислоты и их применение в качестве модуляторов ингибитора активатора плазминогена-1 (pai) для лечения тромбоза и сердечно-сосудистых заболеваний
RU2008150440A (ru) * 2006-05-29 2010-07-20 Никокс С.А. (Fr) Гетероциклические нитрованные соединения в качестве антагонистов рецептора эндотелина
CN104146998A (zh) * 2014-08-05 2014-11-19 广东食品药品职业学院 5-羟基-7-甲氧基色原酮在制药中的新应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3700661A (en) * 1968-11-22 1972-10-24 Hoffmann La Roche Total steroid synthesis employing substituted isoxazole derivatives
CH641464A5 (de) * 1979-11-22 1984-02-29 Lonza Ag Verfahren zur herstellung von 4-amino-6-hydroxy-3-phenyl-isoxazolo(5,4-b)pyridin-5-carbonitrilen.
EP0403158A3 (de) * 1989-06-14 1991-12-18 Smithkline Beecham Corporation Imidazolyl-Alkensäuren
WO1994002474A1 (en) * 1992-07-17 1994-02-03 Smithkline Beecham Corporation Endothelin receptor antagonists
WO1994027597A1 (en) * 1993-05-21 1994-12-08 Smithkline Beecham Corporation Imidazolyl-alkenoic acid angiotensin ii receptor antagonists
US5541213A (en) * 1993-06-24 1996-07-30 Eisai Co., Ltd. Propenoic acid derivatives diazole propenoic acid compounds which have useful pharmaceutical utility
EP0778833B1 (de) * 1994-09-02 2002-05-15 SmithKline Beecham Corporation Endothelin-rezeptor-antagonisten

Also Published As

Publication number Publication date
ES2195002T3 (es) 2003-12-01
WO1997004774A1 (en) 1997-02-13
DE69626986T2 (de) 2004-02-05
EP0841926A4 (de) 1999-08-04
EP0841926B1 (de) 2003-03-26
JPH11513022A (ja) 1999-11-09
EP0841926A1 (de) 1998-05-20

Similar Documents

Publication Publication Date Title
NO961072L (no) Endotelinreseptorantagonister
DE69633171D1 (de) Mutierte luziferasen
DE69623578D1 (de) Kappsägeschlitten
DE69616364T2 (de) Endothelinrezeptorantagonisten
DE69619116T2 (de) Endothelinrezeptorantagonisten
NO963131D0 (no) Endotelinreseptorantagonister
NO963213D0 (no) Endotelinreseptorantagonister
DE69626986D1 (de) Endothelinrezeptorantagonist
DE69628924D1 (de) Endothelinrezeptorantagonisten
ATA119896A (de) Scheibenmähwerk
BR9501643A (pt) Helistato
FI954179A (fi) Perferointilaite
SE9501165D0 (sv) Hållaranordning
FI2247U1 (fi) Samlingsmedel
FI2022U1 (fi) Jaktkula
KR960030307U (ko) 다시
FIU950164U0 (fi) Tankningsanordning
BR7500991U (pt) Caríndio
BR7501376U (pt) Massarreal
BR7500838U (pt) Vassourágua
BR7500825U (pt) Chutegol
BR7501303U (pt) Dupla-embalagem
BR7500809U (pt) Tele-negocios
BR7500703U (pt) Rodopratic
NO954673D0 (no) Mönsterstokk

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SMITHKLINE BEECHAM CORP., PHILADELPHIA, PA., US

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee