DE69624726D1 - Chitosan-impfstoff-zusammensetzungen zur intranasalen verabreichung und anwendungen - Google Patents

Chitosan-impfstoff-zusammensetzungen zur intranasalen verabreichung und anwendungen

Info

Publication number
DE69624726D1
DE69624726D1 DE69624726T DE69624726T DE69624726D1 DE 69624726 D1 DE69624726 D1 DE 69624726D1 DE 69624726 T DE69624726 T DE 69624726T DE 69624726 T DE69624726 T DE 69624726T DE 69624726 D1 DE69624726 D1 DE 69624726D1
Authority
DE
Germany
Prior art keywords
chitosan
intranasal administration
applications
vaccine compositions
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69624726T
Other languages
English (en)
Other versions
DE69624726T2 (de
Inventor
Lisbeth Illum
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyowa Kirin Services Ltd
Original Assignee
West Pharmaceutical Services Drug Delivery and Clinical Research Center Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by West Pharmaceutical Services Drug Delivery and Clinical Research Center Ltd filed Critical West Pharmaceutical Services Drug Delivery and Clinical Research Center Ltd
Application granted granted Critical
Publication of DE69624726D1 publication Critical patent/DE69624726D1/de
Publication of DE69624726T2 publication Critical patent/DE69624726T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
DE69624726T 1995-12-07 1996-12-09 Chitosan-impfstoff-zusammensetzungen zur intranasalen verabreichung und anwendungen Expired - Lifetime DE69624726T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9525083.3A GB9525083D0 (en) 1995-12-07 1995-12-07 Vaccine compositions
PCT/GB1996/003019 WO1997020576A1 (en) 1995-12-07 1996-12-09 Vaccine compositions for intranasal administration comprising chitosan and use thereof

Publications (2)

Publication Number Publication Date
DE69624726D1 true DE69624726D1 (de) 2002-12-12
DE69624726T2 DE69624726T2 (de) 2003-09-18

Family

ID=10785093

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69624726T Expired - Lifetime DE69624726T2 (de) 1995-12-07 1996-12-09 Chitosan-impfstoff-zusammensetzungen zur intranasalen verabreichung und anwendungen

Country Status (13)

Country Link
US (2) US6391318B1 (de)
EP (1) EP0865297B1 (de)
JP (1) JP4063876B2 (de)
AT (1) ATE227134T1 (de)
CA (1) CA2237529C (de)
DE (1) DE69624726T2 (de)
DK (1) DK0865297T3 (de)
ES (1) ES2186809T3 (de)
GB (2) GB9525083D0 (de)
NO (1) NO323084B1 (de)
NZ (1) NZ323973A (de)
PT (1) PT865297E (de)
WO (1) WO1997020576A1 (de)

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US6777000B2 (en) * 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
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GB0302218D0 (en) 2003-01-30 2003-03-05 Chiron Sri Vaccine formulation & Mucosal delivery
AU2003239744B2 (en) * 2002-05-14 2008-07-03 Novartis Vaccines And Diagnostics S.R.L. Mucosal combination vaccines for bacterial meningitis
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WO2004075829A2 (en) * 2003-01-30 2004-09-10 Chiron Corporation Adjuvanted influenza vaccine
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WO2004076664A2 (en) * 2003-02-21 2004-09-10 University Of South Florida Vectors for regulating gene expression
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US20040248804A1 (en) * 2003-05-01 2004-12-09 Khurshid Iqbal Nasal administration of the LH-RH analog Leuprolide
WO2005000222A2 (en) * 2003-05-30 2005-01-06 Amylin Pharmaceuticals, Inc. Novel methods and compositions for enhanced transmucosal delivery of peptides and proteins
GB0315632D0 (en) * 2003-07-04 2003-08-13 West Pharm Serv Drug Res Ltd Pharmaceutical formulations
EP1689414A4 (de) * 2003-12-04 2009-04-08 Univ South Florida Res Foundat Polynucleotide zur reduzierung der genexpression des respiratory syncytial virus
US7968122B2 (en) * 2003-12-10 2011-06-28 Adventrx Pharmaceuticals, Inc. Anti-viral pharmaceutical compositions
US20050129679A1 (en) * 2003-12-15 2005-06-16 Nastech Pharmaceutical Company Inc. Method for opening tight junctions
US7740883B2 (en) * 2004-03-28 2010-06-22 University Of Debrecen Nanoparticles from chitosan
CA2565236A1 (en) * 2004-05-06 2005-11-17 Ivrea Pharmaceuticals, Inc. Particles for the delivery of active agents
US20090069226A1 (en) * 2004-05-28 2009-03-12 Amylin Pharmaceuticals, Inc. Transmucosal delivery of peptides and proteins
US20050283004A1 (en) 2004-06-18 2005-12-22 Hopax Chemicals Manufacturing Co., Ltd. Alkylsulfonated polyaminosaccharides
KR20070057932A (ko) * 2004-09-15 2007-06-07 오츠카 세이야쿠 가부시키가이샤 경점막용 조성물, 및 경점막 흡수의 향상 방법
US20070036867A1 (en) * 2005-05-23 2007-02-15 University Of South Florida Controlled and Sustained Gene Transfer Mediated by Thiol-Modified Polymers
US20070031512A1 (en) * 2005-08-03 2007-02-08 Amcol International Corporation Virus-interacting layered phyllosilicates and methods of inactivating viruses
US20100272769A1 (en) * 2005-08-03 2010-10-28 Amcol International Virus-, Bacteria-, and Fungi-Interacting Layered Phyllosilicates and Methods of Use
US20080184618A1 (en) * 2005-08-03 2008-08-07 Amcol International Virus-Interacting Layered Phyllosilicates and Methods of Use
US8536324B2 (en) * 2005-10-21 2013-09-17 University Of South Florida Method of drug delivery by carbon nanotube-chitosan nanocomplexes
EP1948810A4 (de) * 2005-11-04 2010-06-30 Biosyntech Canada Inc Zusammensetzung und verfahren zur effizienten verabreichung von nukleinsäuren in zellen mithilfe von chitosan
EP1965787B1 (de) 2005-11-30 2013-04-10 Endo Pharmaceuticals Inc. Behandlung der Xerostomie mit einem schwefelhaltigen Antioxidant
NZ571965A (en) * 2006-03-30 2012-02-24 Engene Inc Chitosan-based nanoparticles and methods for transfecting gut cells in vivo
AU2007262845B2 (en) 2006-06-20 2013-07-25 Mucovax Inc. Compositions comprising chitin microparticles and their medical uses
LT2601970T (lt) * 2006-09-29 2017-04-25 Takeda Vaccines, Inc. Vakcinos prieš noro virusą kompozicijos
WO2008091588A1 (en) 2007-01-22 2008-07-31 Targacept, Inc. Intranasal, buccal, and sublingual administration of metanicotine analogs
US20080182819A1 (en) * 2007-01-29 2008-07-31 Act Iii Licensing, Llc Chitosan compositions and methods for using chitosan compositions in the treatment of health disorders
ES2372652T3 (es) 2007-05-23 2012-01-25 Amcol International Corporation Filosilicatos estratificados, que interactúan con el colesterol y métodos para reducir la hipercolesterolemia en un mamífero.
US20100266636A1 (en) * 2007-09-18 2010-10-21 Ligocyte Pharmaceuticals, Inc. Method of conferring a protective immune response to norovirus
KR20100083150A (ko) * 2007-09-18 2010-07-21 리고사이트 파머슈티컬즈 인코퍼레이티드 노로바이러스에 대한 보호면역반응을 제공하는 방법
WO2009089535A2 (en) * 2008-01-11 2009-07-16 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Polypeptide vaccine and vaccination strategy against mycobacterium
WO2009108867A1 (en) 2008-02-27 2009-09-03 Amcol International Corporation Methods of treating cardiovascular disorders associated with atherosclerosis
CN102177233B (zh) * 2008-08-08 2015-04-15 莱戈赛特医药股份有限公司 用于增强交叉反应性的包含复合衣壳氨基酸序列的病毒样颗粒
EP2419132B1 (de) * 2009-04-15 2014-06-25 Ceva Sante Animale Rekombinantes hühne-herpesvirus und impfstoff zur immunisierung von wasservögeln
CR20190540A (es) 2011-07-11 2022-04-04 Takeda Vaccines Inc FORMULACIONES PARENTERALES DE VACUNAS CONTRA LOS NOVOVIRUS (Divisional 2014-0069)
US10279028B2 (en) 2012-04-24 2019-05-07 Ohio State Innovation Foundation Compositions and methods for treating and preventing porcine reproductive and respiratory syndrome
DK2841097T3 (da) 2012-04-24 2022-11-28 Ohio State Innovation Foundation Sammensætninger og fremgangsmåder til behandling og forebyggelse af porcint reproduktions- og respirationssyndrom
CN108715607B (zh) * 2018-04-12 2021-12-10 华南农业大学 重组霍乱毒素b亚基蛋白、pedv灭活疫苗及制备与应用
CN109172817B (zh) * 2018-08-16 2021-10-26 华中农业大学 猪流行性腹泻病毒减毒活疫苗壳聚糖微球的制备方法及其应用
EP3698773A1 (de) 2019-02-21 2020-08-26 Università degli Studi di Parma Zusammensetzung und herstellung von pulvern mit nanoadjuvanzien zur mukosalen impfung

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Also Published As

Publication number Publication date
JP2000501412A (ja) 2000-02-08
EP0865297A1 (de) 1998-09-23
GB9811810D0 (en) 1998-07-29
WO1997020576A1 (en) 1997-06-12
AU1102597A (en) 1997-06-27
NO323084B1 (no) 2006-12-27
JP4063876B2 (ja) 2008-03-19
ATE227134T1 (de) 2002-11-15
NO982497D0 (no) 1998-06-02
PT865297E (pt) 2003-03-31
AU705452B2 (en) 1999-05-20
EP0865297B1 (de) 2002-11-06
DE69624726T2 (de) 2003-09-18
DK0865297T3 (da) 2003-03-03
GB2322801B (en) 2000-01-19
US7323183B2 (en) 2008-01-29
US20030039665A1 (en) 2003-02-27
US6391318B1 (en) 2002-05-21
NZ323973A (en) 2004-12-24
CA2237529A1 (en) 1997-06-12
NO982497L (no) 1998-06-02
ES2186809T3 (es) 2003-05-16
GB9525083D0 (en) 1996-02-07
GB2322801A (en) 1998-09-09
CA2237529C (en) 2008-10-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ARCHIMEDES DEVELOPMENT LTD., NOTTINGHAM, GB

8328 Change in the person/name/address of the agent

Representative=s name: STROHSCHAENK UND KOLLEGEN, 85521 OTTOBRUNN