DE69622936D1 - Vermittler, geeignet für die elektrochemischr Regenierung von NADH, NADPH oder deren Analogen - Google Patents

Vermittler, geeignet für die elektrochemischr Regenierung von NADH, NADPH oder deren Analogen

Info

Publication number
DE69622936D1
DE69622936D1 DE69622936T DE69622936T DE69622936D1 DE 69622936 D1 DE69622936 D1 DE 69622936D1 DE 69622936 T DE69622936 T DE 69622936T DE 69622936 T DE69622936 T DE 69622936T DE 69622936 D1 DE69622936 D1 DE 69622936D1
Authority
DE
Germany
Prior art keywords
nadh
nadph
analogs
electrochemical regeneration
electrochemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69622936T
Other languages
English (en)
Other versions
DE69622936T2 (de
Inventor
Michael L Bloczynski
Paul F Corey
Yingping Deng
Alison J Murray
Metthew K Musho
Hans-Ulrich Siegmund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Application granted granted Critical
Publication of DE69622936D1 publication Critical patent/DE69622936D1/de
Publication of DE69622936T2 publication Critical patent/DE69622936T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01M—PROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSION OF CHEMICAL ENERGY INTO ELECTRICAL ENERGY
    • H01M4/00—Electrodes
    • H01M4/86—Inert electrodes with catalytic activity, e.g. for fuel cells
    • H01M4/90—Selection of catalytic material
    • H01M4/9008—Organic or organo-metallic compounds
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01M—PROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSION OF CHEMICAL ENERGY INTO ELECTRICAL ENERGY
    • H01M8/00—Fuel cells; Manufacture thereof
    • H01M8/16—Biochemical fuel cells, i.e. cells in which microorganisms function as catalysts
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/30—Hydrogen technology
    • Y02E60/50—Fuel cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/817—Enzyme or microbe electrode
DE69622936T 1995-06-06 1996-05-24 Vermittler, geeignet für die elektrochemischr Regenierung von NADH, NADPH oder deren Analogen Expired - Lifetime DE69622936T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/471,745 US5520786A (en) 1995-06-06 1995-06-06 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof

Publications (2)

Publication Number Publication Date
DE69622936D1 true DE69622936D1 (de) 2002-09-19
DE69622936T2 DE69622936T2 (de) 2003-01-02

Family

ID=23872830

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69622936T Expired - Lifetime DE69622936T2 (de) 1995-06-06 1996-05-24 Vermittler, geeignet für die elektrochemischr Regenierung von NADH, NADPH oder deren Analogen

Country Status (6)

Country Link
US (1) US5520786A (de)
EP (1) EP0747984B1 (de)
JP (1) JP3831008B2 (de)
AU (1) AU692387B2 (de)
CA (1) CA2177753C (de)
DE (1) DE69622936T2 (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631371A (en) * 1995-11-22 1997-05-20 Bayer Corporation Method for the preparation of substituted 3-(phenylimino)-3H-phenothiazines and phenoxazines
US5866353A (en) * 1996-12-09 1999-02-02 Bayer Corporation Electro chemical biosensor containing diazacyanine mediator for co-enzyme regeneration
AU8243098A (en) 1998-07-16 2000-02-07 Sapporo Immuno Diagnostic Laboratory Method for assaying l-phenylalanine and l-phenylalanine sensor
US6500571B2 (en) 1998-08-19 2002-12-31 Powerzyme, Inc. Enzymatic fuel cell
DE10024314A1 (de) * 2000-05-17 2001-11-22 Basf Ag Verfahren, umfassend die indirekte elektrochemische Regeneration von NAD(P)H
US20030049511A1 (en) * 2001-04-13 2003-03-13 Rosalyn Ritts Stabilized biocompatible membranes of block copolymers and fuel cells produced therewith
US20030087141A1 (en) * 2001-04-13 2003-05-08 Sun Hoi-Cheong Steve Dual membrane fuel cell
US20030113606A1 (en) * 2001-04-13 2003-06-19 Rosalyn Ritts Biocompatible membranes of block copolymers and fuel cells produced therewith
US20030031911A1 (en) * 2001-04-13 2003-02-13 Rosalyn Ritts Biocompatible membranes and fuel cells produced therewith
US7163616B2 (en) * 2001-09-14 2007-01-16 Bayer Corporation Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes
EP1867732B1 (de) * 2001-09-14 2015-01-28 Bayer HealthCare LLC Reagenzien, Verfahren und Vorrichtungen zum Nachweis von Analyten
MXPA04004194A (es) * 2001-11-02 2005-03-31 Rice University Sistema de recirculacion para la manipulacion de disponibilidad de nadh intracelular.
KR100483624B1 (ko) * 2002-11-01 2005-04-19 학교법인 건국대학교 환경 쇼크를 이용한 미생물 연료전지의 전류량 제어 방법
US7638228B2 (en) * 2002-11-27 2009-12-29 Saint Louis University Enzyme immobilization for use in biofuel cells and sensors
CA2455669A1 (en) * 2003-02-04 2004-08-04 Bayer Healthcare, Llc Method and test strip for determining glucose in blood
JP4839219B2 (ja) * 2003-10-24 2011-12-21 バイエル・ヘルスケア・エルエルシー 酵素的電気化学的バイオセンサ
US8859151B2 (en) 2003-11-05 2014-10-14 St. Louis University Immobilized enzymes in biocathodes
US7244610B2 (en) * 2003-11-14 2007-07-17 Rice University Aerobic succinate production in bacteria
BRPI0507376A (pt) 2004-02-06 2007-07-10 Bayer Healthcare Llc espécie oxidável como uma referência interna para biossensores e método de uso
EP1802962B1 (de) 2004-10-12 2018-06-06 Ascensia Diabetes Care Holdings AG Konzentrationsbestimmung in einer diffusionsbarriereschicht
ATE530906T1 (de) 2004-12-13 2011-11-15 Bayer Healthcare Llc Verfahren zur unterscheidung zwischen einen gemeinsamen analyten enthaltenden blut- und kontrollösungen
WO2006110504A1 (en) 2005-04-08 2006-10-19 Bayer Healthcare Llc Oxidizable species as an internal reference in control solutions for biosensors
US9406959B2 (en) 2005-05-10 2016-08-02 Board Of Trustees Of Michigan State University Electrobiocatalytic reactors having reversible bioelectronic interfaces and methods and devices related thereto
US8435773B2 (en) * 2005-05-10 2013-05-07 Board Of Trustees Of Michigan State University Customizable and renewable nanostructured interface for bioelectronic applications
EP1913374B1 (de) 2005-07-20 2019-01-09 Ascensia Diabetes Care Holdings AG Verfahren zur signalisierung des benutzers zum hinzufügen einer zusätzlichen probe zu einem prüfstreifen, verfahren zum messen der temperatur einer probe und verfahren zur bestimmung der konzentration eines analyten auf basis von puls-amperometrie
KR101477948B1 (ko) 2005-09-30 2014-12-30 바이엘 헬스케어 엘엘씨 게이트형 전압 전류 측정 분석 구간 결정 방법
KR20080080105A (ko) 2005-11-02 2008-09-02 세인트 루이스 유니버시티 바이오애노드, 바이오캐소드 및 바이오연료 전지 내의효소를 사용하는 직접 전자 전달
JP5399892B2 (ja) * 2006-04-07 2014-01-29 ダウ グローバル テクノロジーズ エルエルシー リチウム充電式電気化学電池
EP2089531B1 (de) 2006-09-22 2019-07-10 Ascensia Diabetes Care Holdings AG Biosensorsystem mit verbesserter stabilität und hämatokrit-ausführung
BRPI0717620A2 (pt) 2006-10-24 2013-10-22 Bayer Healthcare Llc Amperometria de decaimento transitório
EP3660499A1 (de) 2007-09-24 2020-06-03 Ascensia Diabetes Care Holdings AG Mehrteilige und potentialtestsensoren, verfahren und systeme
JP5856371B2 (ja) * 2007-12-10 2016-02-09 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅＬＬＣ 分析対象物を検出するための試薬及び方法
WO2009076268A1 (en) * 2007-12-10 2009-06-18 Bayer Healthcare Llc Process of making 3-phenylimino-3h-phenothiazine or 3-phenylimino-3h-phenoxazine mediator
WO2009076302A1 (en) 2007-12-10 2009-06-18 Bayer Healthcare Llc Control markers for auto-detection of control solution and methods of use
EP3369825B1 (de) 2007-12-10 2021-07-28 Ascensia Diabetes Care Holdings AG Poröse partikelreagenzzusammensetzungen und vorrichtungen für biosensoren
US8008037B2 (en) * 2008-03-27 2011-08-30 Roche Diagnostics Operations, Inc. Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline
US20090305317A1 (en) * 2008-06-05 2009-12-10 Brauer Jacob S User interface for testing device
US8679772B2 (en) * 2008-06-06 2014-03-25 Agency For Science, Technology And Research Immunoassay
CN103760213B (zh) 2008-07-10 2016-04-13 拜尔健康护理有限责任公司 具有电流分析法及伏安分析法的工作循环的系统及方法
JP5773883B2 (ja) 2008-12-08 2015-09-02 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅＬＬＣ バイオセンサのための低全塩試薬組成物およびシステム
WO2010141359A2 (en) * 2009-06-01 2010-12-09 Bayer Healthcare Llc Redox molecules and methods of making the same
RU2583133C2 (ru) 2009-11-10 2016-05-10 БАЙЕР ХЕЛТКЭА ЭлЭлСи Система распознавания недостаточного заполнения для биосенсора
WO2011075575A1 (en) 2009-12-17 2011-06-23 Bayer Healthcare Llc Transdermal systems, devices, and methods to optically analyze an analyte
US20120252046A1 (en) 2009-12-17 2012-10-04 Bayer Healthcare Llc Transdermal systems, devices, and methods for biological analysis
US9233788B2 (en) 2010-01-22 2016-01-12 Bayer Healthcare Llc Biosensor desiccant system having enhanced measurement performance
WO2011150155A1 (en) 2010-05-28 2011-12-01 Bayer Healthcare Llc Polymer bonded redox molecules and methods of making the same
EP2619192A1 (de) 2010-09-23 2013-07-31 Bayer HealthCare LLC Radikalisch polymerisierbares phenothiazinmakromonomer zur verwendung bei der beschichtung von medizinprodukten
TWI565943B (zh) 2011-07-22 2017-01-11 拜耳保健公司 具有增進測量性能之生物感測器乾燥劑系統
KR101355127B1 (ko) * 2011-09-30 2014-01-29 주식회사 아이센스 전기화학적 바이오센서용 산화환원반응 시약조성물 및 이를 포함하는 바이오센서
US20130284609A1 (en) * 2012-04-30 2013-10-31 Lifescan Scotland Limited Enzymatic electrochemical-based sensors with nad polymeric coenzyme
CN105026558B (zh) 2013-01-28 2020-05-15 霍夫曼-拉罗奇有限公司 衍生自黑曲霉的新型葡萄糖氧化酶
CN113058621B (zh) * 2019-12-12 2022-02-15 中国科学院大连化学物理研究所 还原型辅酶及其类似物再生催化剂以及制备方法、应用
CN114981271A (zh) 2019-12-26 2022-08-30 爱-森新株式会社 新型有机电子转移介体和包括其的装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3279215D1 (en) * 1981-04-08 1988-12-15 Jagfeldt Hans Electrode for the electrochemical regeneration of co-enzyme, a method of making said electrode, and the use thereof
GB8424709D0 (en) * 1984-10-01 1984-11-07 Minnesota Mining & Mfg Azine redox dyes and leuco azine dyes
US5192631A (en) * 1987-03-18 1993-03-09 Dai Nippon Insatsu Kabushiki Kaisha Variable electroconductivity material
IL102930A (en) * 1992-08-25 1997-03-18 Yissum Res Dev Co Electrobiochemical analytical method and electrodes
US5393615A (en) * 1994-02-03 1995-02-28 Miles Inc. Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof
JPH08304329A (ja) * 1995-05-09 1996-11-22 Kdk Corp 多孔性膜を使用したバイオセンサー、および該多孔性膜の 製造方法

Also Published As

Publication number Publication date
AU692387B2 (en) 1998-06-04
AU5475096A (en) 1996-12-19
CA2177753A1 (en) 1996-12-07
EP0747984A3 (de) 1997-07-16
EP0747984B1 (de) 2002-08-14
US5520786A (en) 1996-05-28
JPH08334490A (ja) 1996-12-17
DE69622936T2 (de) 2003-01-02
CA2177753C (en) 2004-07-27
JP3831008B2 (ja) 2006-10-11
EP0747984A2 (de) 1996-12-11

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