DE69614127D1 - Eine familie von verbindungen mit entzündungshemmender und antiviraler aktivität und deren zusammensetzungen alleine oder in verbindung mit inhibitoren der reversen transcriptase zur inhibierung, vermeidung oder eliminierung viraler replikation und methoden zu ihrer verwendung - Google Patents

Eine familie von verbindungen mit entzündungshemmender und antiviraler aktivität und deren zusammensetzungen alleine oder in verbindung mit inhibitoren der reversen transcriptase zur inhibierung, vermeidung oder eliminierung viraler replikation und methoden zu ihrer verwendung

Info

Publication number
DE69614127D1
DE69614127D1 DE69614127T DE69614127T DE69614127D1 DE 69614127 D1 DE69614127 D1 DE 69614127D1 DE 69614127 T DE69614127 T DE 69614127T DE 69614127 T DE69614127 T DE 69614127T DE 69614127 D1 DE69614127 D1 DE 69614127D1
Authority
DE
Germany
Prior art keywords
inflammatory
reverse transcriptase
family
inhibitors
inhibit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69614127T
Other languages
English (en)
Inventor
Farid Hamedi-Sangsari
Fabienne Nugier
Thierry Vallet
Jacques Grange
Jorge Vila
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Compagnie de Developpement Aguettant SA
Original Assignee
Compagnie de Developpement Aguettant SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Compagnie de Developpement Aguettant SA filed Critical Compagnie de Developpement Aguettant SA
Application granted granted Critical
Publication of DE69614127D1 publication Critical patent/DE69614127D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69614127T 1995-09-15 1996-09-13 Eine familie von verbindungen mit entzündungshemmender und antiviraler aktivität und deren zusammensetzungen alleine oder in verbindung mit inhibitoren der reversen transcriptase zur inhibierung, vermeidung oder eliminierung viraler replikation und methoden zu ihrer verwendung Expired - Lifetime DE69614127D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52887995A 1995-09-15 1995-09-15
US08/600,525 US5705522A (en) 1995-09-15 1996-02-13 Compounds having anti-inflammatory and anti-viral activity, compositions of these, alone and in combination with reverse transcriptase inhibitors
PCT/IB1996/000942 WO1997010205A1 (en) 1995-09-15 1996-09-13 A new family of compounds having anti-inflammatory and anti-viral activity and compositions of these, alone and in combination with reverse transcriptase inhibitors, for inhibiting, preventing or eliminating viral replication and methods of using same

Publications (1)

Publication Number Publication Date
DE69614127D1 true DE69614127D1 (de) 2001-08-30

Family

ID=27062862

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69614127T Expired - Lifetime DE69614127D1 (de) 1995-09-15 1996-09-13 Eine familie von verbindungen mit entzündungshemmender und antiviraler aktivität und deren zusammensetzungen alleine oder in verbindung mit inhibitoren der reversen transcriptase zur inhibierung, vermeidung oder eliminierung viraler replikation und methoden zu ihrer verwendung

Country Status (8)

Country Link
US (1) US5705522A (de)
EP (1) EP0854860B1 (de)
JP (1) JP2000511871A (de)
AT (1) ATE203513T1 (de)
AU (1) AU6835096A (de)
CA (1) CA2231996A1 (de)
DE (1) DE69614127D1 (de)
WO (1) WO1997010205A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194391B1 (en) * 1998-06-24 2001-02-27 Emory University 3′-azido-2′,3′-dideoxyuridine administration to treat HIV and related test protocol
SK11922002A3 (sk) * 2000-02-18 2003-06-03 Shire Biochem Inc. Použitie analógov nukleozidov na liečenie alebo prevenciu infekcií spôsobených flavivírusom
US20050087555A1 (en) * 2003-10-28 2005-04-28 Hatton Jason D. Fluid dispensing components
AU2006326404B2 (en) * 2005-12-14 2011-11-03 Ambrx, Inc. Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
PT2691530T (pt) 2011-06-10 2018-05-10 Univ Oregon Health & Science Glicoproteínas e vectores recombinantes cmv

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ216172A (en) * 1985-05-15 1989-08-29 Wellcome Found Nucleosides and pharmaceutical compositions
JPS62501712A (ja) * 1985-08-26 1987-07-09 アメリカ合衆国 ２′、３′―ジデオキシイノシン、２′，３′―ジデオキシグアノシンまたは２′，３′―ジデオキシアデノシンを含有する抗ｈｔｌｖ―３／ｌａｖ剤
US5254539A (en) * 1985-08-26 1993-10-19 U.S. Government, Dept. Of Health And Human Services, C/O National Institutes Of Health Method of treating HIV with 2',3'-dideoxyinosine
FR2646348A1 (fr) * 1989-04-28 1990-11-02 Inst Nat Sante Rech Med D-aspartique acide-hydroxamate en tant que medicament
US5571839A (en) * 1989-04-28 1996-11-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) D-aspartic acid β-hydroxamate for the treatment of viral infections and tumors
GB9208428D0 (en) * 1992-04-16 1992-06-03 Proteus Molecular Design Synthetic polypeptides
DE69433953T2 (de) * 1993-05-21 2005-08-25 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Neues Verfahen zur Hemmung der Replikation der virusabhängigen reversen Transkriptase durch Verwendung von Didesoxynukleotid-Synthese Inhibitoren
AU1249595A (en) * 1993-12-20 1995-07-17 Compagnie De Developpment Mixtures of dideoxynucleosides and d-aspartic acid beta-hydroxamate for inhibiting retroviral spread

Also Published As

Publication number Publication date
JP2000511871A (ja) 2000-09-12
US5705522A (en) 1998-01-06
ATE203513T1 (de) 2001-08-15
EP0854860B1 (de) 2001-07-25
AU6835096A (en) 1997-04-01
WO1997010205A1 (en) 1997-03-20
CA2231996A1 (en) 1997-03-20
EP0854860A1 (de) 1998-07-29

Similar Documents

Publication Publication Date Title
DK0735890T3 (da) Blandinger af 2',3'-dideoxyinosin og hydroxycarbamid til hæmning af retroviral spredning
DE3587434D1 (de) Antivirale pharmazeutische zusammensetzungen und ihrer verwendung.
BG102048A (en) Tetrahydrofuran-containing sulphonamides as aspartylprotease inhibitors
KR880010777A (ko) 바이러스 억제제와 결합한 dsRNA로 인간의 바이러스 감염을 치료하는 방법
MX9403380A (es) Inhibidores de proteasa de vih utiles para el tratamiento de sida.
ATE298741T1 (de) Polyaromatische verbindungen zur behandlung von herpes-infektionen
ATE227133T1 (de) Verwendung von interferon-alpha 8 subtype zur herstellung von medikamenten zur behandlung von viralinfektionen der leber
DE60022380D1 (de) Verwendung von einem trifluridin derivat allein oder in kombination mit einem thymidin-phosphorylase-hemmer zur behandlung von hiv
PT88248A (pt) Processo para a preparacao de composicoes farmaceuticas contendo rnas de cadeia dupla com actividade topica
DE60036862D1 (de) Synergistische hemmung von viralreplikation durch langkettigen kohlenwasserstoffe und nucleosid-analoge
DE69614127D1 (de) Eine familie von verbindungen mit entzündungshemmender und antiviraler aktivität und deren zusammensetzungen alleine oder in verbindung mit inhibitoren der reversen transcriptase zur inhibierung, vermeidung oder eliminierung viraler replikation und methoden zu ihrer verwendung
DE3686108T2 (de) Verwendung von p-chlorophenoxyazetat von n,n-dimethylbiguanid zur behandlung von neuropathien und nervendegeneration.
AR009935A1 (es) Un compuesto efectivo para inhibir aspartilproteasa, composiciones que lo incorporan y metodos para prevenir o tratar infecciones con hiv
KR890009389A (ko) 바이러스를 억제시키는 방법
ES2103577T3 (es) Compuestos antiviricos de naftoquinona, composiciones que los contienen y utilizaciones de estos compuestos.
ES2113888T3 (es) Sulfatos de dextrina como agentes anti hiv-1 y composicion de los mismos.
DE69232417T2 (de) Michellamine zur verwendung als antivirale wirkstoffe, zusammensetzung und behandlungsverfahren
ES2134259T3 (es) Compuestos antiviricos calanolidas, composiciones y utilizacion de los mismos.
DE3767308D1 (de) Verwendung von sulfonamidderivaten zur herstellung eines antivirusmittels.
PA8441101A1 (es) Composiciones farmaceuticas
ATE179601T1 (de) Aufheben der resistenz von hiv-1 linien gegenüber zidovudine
FR2647792B1 (de)
ATE114115T1 (de) Verwendung von 5,6-dihydro-dibenz(b,e>azepin-6,11-dion-11-oxim n zur herstellungvon antiretroviralen mitteln.
GR1000618B (el) Μεθοδος αναστολης hiv χρησιμοποιωντας συνεργιστικους συνδυασμους νουκλεοσιδικων παραγωγων.
DE68929084D1 (de) Arzneimittel zur Verhinderung einer Infektion mit dem für AIDS verantwortlichen Virus

Legal Events

Date Code Title Description
8332 No legal effect for de