DE69612413D1 - 1-(Hetero)Arylvinyl-5H-2,3-benzodiazepinderivative verwendbar zur Behandlung von Erkrankungen des Zentralnervensystems, sowie Benzopyrylium Intermediate zu ihrer Herstellung - Google Patents

1-(Hetero)Arylvinyl-5H-2,3-benzodiazepinderivative verwendbar zur Behandlung von Erkrankungen des Zentralnervensystems, sowie Benzopyrylium Intermediate zu ihrer Herstellung

Info

Publication number
DE69612413D1
DE69612413D1 DE69612413T DE69612413T DE69612413D1 DE 69612413 D1 DE69612413 D1 DE 69612413D1 DE 69612413 T DE69612413 T DE 69612413T DE 69612413 T DE69612413 T DE 69612413T DE 69612413 D1 DE69612413 D1 DE 69612413D1
Authority
DE
Germany
Prior art keywords
sub
alkoxy
group
nervous system
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69612413T
Other languages
English (en)
Other versions
DE69612413T2 (de
Inventor
Dr Vago
Dr Reiter
Dr Gyertyan
Istvan Gacsalyi
Dr Bilkei-Gorzo
Dr Egyed
Dr Andrasi
Dr Bakonyi
Dr Berzsensyi
Peter Botka
Dr Hamori
Haskane Dr Salamon
Dr Horvath
Dr Koeroesi
Dr Mate
Imre Moravcsik
Dr Szentkuti
Dr Zolyomi
Dr Blasko
Kazone Klara Daroczi
Dr Simig
Dr Tihanyi
Dr Bajnogel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU9500386A external-priority patent/HU224435B1/hu
Priority claimed from HU9500385A external-priority patent/HU224438B1/hu
Priority claimed from HU9503353A external-priority patent/HU221508B/hu
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of DE69612413D1 publication Critical patent/DE69612413D1/de
Application granted granted Critical
Publication of DE69612413T2 publication Critical patent/DE69612413T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69612413T 1995-02-09 1996-02-09 1-(Hetero)Arylvinyl-5H-2,3-benzodiazepinderivative verwendbar zur Behandlung von Erkrankungen des Zentralnervensystems, sowie Benzopyrylium Intermediate zu ihrer Herstellung Expired - Fee Related DE69612413T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU9500386A HU224435B1 (hu) 1995-02-09 1995-02-09 Benzodiazepin-származékok, eljárás előállításukra, alkalmazásukra és ezeket tartalmazó gyógyászati készítmények
HU9500385A HU224438B1 (hu) 1995-02-09 1995-02-09 Benzodiazepin-származékok, eljárás előállításukra, alkalmazásuk és ezeket tartalmazó gyógyászati készítmények
HU9503353A HU221508B (en) 1995-11-24 1995-11-24 1-vinyl-5h-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them, process for the preparation of the compounds and intermediates

Publications (2)

Publication Number Publication Date
DE69612413D1 true DE69612413D1 (de) 2001-05-17
DE69612413T2 DE69612413T2 (de) 2001-09-27

Family

ID=27270110

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69612413T Expired - Fee Related DE69612413T2 (de) 1995-02-09 1996-02-09 1-(Hetero)Arylvinyl-5H-2,3-benzodiazepinderivative verwendbar zur Behandlung von Erkrankungen des Zentralnervensystems, sowie Benzopyrylium Intermediate zu ihrer Herstellung

Country Status (3)

Country Link
EP (2) EP0726257B1 (de)
AT (1) ATE200487T1 (de)
DE (1) DE69612413T2 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE761315A (de) * 1970-01-12 1971-07-07 S M B Anciens Etablissements J
HU179018B (en) * 1978-10-19 1982-08-28 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivatives
HU186760B (en) * 1981-03-12 1985-09-30 Gyogyszerkutato Intezet Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives
HU195788B (en) * 1986-05-21 1988-07-28 Gyogyszerkutato Intezet Process for producing 1-/hydroxy-stiryl/-5h-2,3-benzobiazepines and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0726257A1 (de) 1996-08-14
EP0726257B1 (de) 2001-04-11
DE69612413T2 (de) 2001-09-27
EP0726256A1 (de) 1996-08-14
ATE200487T1 (de) 2001-04-15

Similar Documents

Publication Publication Date Title
ATE246190T1 (de) Heterozyklische verbindungen, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen die diese enthalten und ihre anwendung in der behandlung von diabetis und verwandten krankheiten
YU40300A (sh) Aril fuzirana azapoliciklična jedinjenja
BG105177A (en) Novel substituted pyrazole derivatives
DE60143493D1 (de) 2-Oxo-1-Pyrrolidin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung.
NO992400L (no) Nye substituerte pyrazolderivater
AU6226494A (en) Spiroazacyclic derivatives as substance p antagonists
NO995006D0 (no) Nye forbindelser
NO991732L (no) Nye heterocyklylmetylsubstituerte pyrazolderivater
ES2164920T3 (es) Nuevos derivados heterociclicos y uso medicinal de los mismos.
ES2141957T3 (es) Uso de raloxifeno y sus analogos para la produccion de un medicamento para el tratamiento de enfermedades virales.
UY24608A1 (es) Procedimiento para la preparación de nuevos compuestos.
YU64400A (sh) Aril fuzirana azapoliciklična jedinjenja
ES2191099T3 (es) Derivados de hidantoina como productos intermedios para principios activos farmaceuticos.
ATE184793T1 (de) Die verwendung von carbostyrilderivaten zur herstellung eines arzneimittels zur hemmung der produktion von interleukin-8
DE69526726T2 (de) Tetrasubstituierte imidazolderivate, verfahren zu ihrer herstellung, ihre anwendung als medikamente und diese enthaltende pharmazeutischen zusammensetzungen
DE69227583T2 (de) Arylmorpholine, herstellung und verwendung
DE69612413D1 (de) 1-(Hetero)Arylvinyl-5H-2,3-benzodiazepinderivative verwendbar zur Behandlung von Erkrankungen des Zentralnervensystems, sowie Benzopyrylium Intermediate zu ihrer Herstellung
AU1191597A (en) Arylethanolamine derivatives and their use as agonists of atypical beta-adrenoceptors
ATE214375T1 (de) Piperazinylalkylthiopyrimidin derivate, diese enthaltende pharmazeutische zusammensetzungen und verfahren zu deren herstellung
DE59607683D1 (de) Neue borneolderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
FR2744444B1 (fr) Nouveaux composes biphenyles, procede et intermediaires de preparation, application a titre de medicaments et compositions pharmaceutiques les renfermant
CA2169115A1 (en) 1-¬2-(substituted vinyl)|-5h-2,3-benzodiazepine derivatives
TH30603A (th) สารประกอบแบบใหม่
NO308304B1 (no) Nye 5H-thiazol[3,2-a]pyrimidin-5-on derivater, anvendelse derav for fremstilling av farmasøytiske sammensetninger, farmasøytiske sammensetninger inneholdende derivatene, samt et preparat til behandling av psykose, schizofreni og angst

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee