DE69611287D1 - Formulierungen von verbindungen als nanopartikel dispergiert in verdaubaren ölen oder fettsäuren - Google Patents

Formulierungen von verbindungen als nanopartikel dispergiert in verdaubaren ölen oder fettsäuren

Info

Publication number
DE69611287D1
DE69611287D1 DE69611287T DE69611287T DE69611287D1 DE 69611287 D1 DE69611287 D1 DE 69611287D1 DE 69611287 T DE69611287 T DE 69611287T DE 69611287 T DE69611287 T DE 69611287T DE 69611287 D1 DE69611287 D1 DE 69611287D1
Authority
DE
Germany
Prior art keywords
formulations
compounds
fatty acids
nanoparticles dispersed
digestible oils
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69611287T
Other languages
English (en)
Other versions
DE69611287T2 (de
Inventor
Mark Eickhoff
R Mueller
A Engers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elan Pharma International Ltd
Original Assignee
Elan Pharma International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/384,057 external-priority patent/US5571536A/en
Priority claimed from US08/388,088 external-priority patent/US5560931A/en
Application filed by Elan Pharma International Ltd filed Critical Elan Pharma International Ltd
Publication of DE69611287D1 publication Critical patent/DE69611287D1/de
Application granted granted Critical
Publication of DE69611287T2 publication Critical patent/DE69611287T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Fats And Perfumes (AREA)
  • Edible Oils And Fats (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69611287T 1995-02-06 1996-01-31 Formulierungen von verbindungen als nanopartikel dispergiert in verdaubaren ölen oder fettsäuren Expired - Fee Related DE69611287T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/384,057 US5571536A (en) 1995-02-06 1995-02-06 Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids
US08/388,088 US5560931A (en) 1995-02-14 1995-02-14 Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids
PCT/US1996/001433 WO1996024332A1 (en) 1995-02-06 1996-01-31 Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids

Publications (2)

Publication Number Publication Date
DE69611287D1 true DE69611287D1 (de) 2001-01-25
DE69611287T2 DE69611287T2 (de) 2001-08-09

Family

ID=27010448

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69611287T Expired - Fee Related DE69611287T2 (de) 1995-02-06 1996-01-31 Formulierungen von verbindungen als nanopartikel dispergiert in verdaubaren ölen oder fettsäuren

Country Status (11)

Country Link
EP (1) EP0808154B1 (de)
JP (1) JPH10513200A (de)
AT (1) ATE198148T1 (de)
AU (1) AU4862796A (de)
CA (1) CA2207304A1 (de)
DE (1) DE69611287T2 (de)
DK (1) DK0808154T3 (de)
ES (1) ES2154806T3 (de)
GR (1) GR3035613T3 (de)
PT (1) PT808154E (de)
WO (1) WO1996024332A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2736550B1 (fr) 1995-07-14 1998-07-24 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule
US6045829A (en) * 1997-02-13 2000-04-04 Elan Pharma International Limited Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers
JP4709378B2 (ja) * 1998-03-30 2011-06-22 オバン・エナジー・リミテッド 水不溶性物質のマイクロ粒子を製造するための組成物及び方法
US6337092B1 (en) 1998-03-30 2002-01-08 Rtp Pharma Inc. Composition and method of preparing microparticles of water-insoluble substances
US7037528B2 (en) 2000-12-22 2006-05-02 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US20050048126A1 (en) 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
JP2005504090A (ja) 2001-09-26 2005-02-10 バクスター・インターナショナル・インコーポレイテッド 分散体および溶媒相または液相の除去によるサブミクロンサイズ−ナノ粒子の調製
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
WO2010079037A2 (de) * 2008-12-18 2010-07-15 Basf Se Wässrige dispersion umfassend pestizidpartikel und amphiphil

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2714065A1 (de) * 1977-03-30 1978-10-12 Boehringer Mannheim Gmbh Instillationszubereitung
DE3623376A1 (de) * 1986-07-11 1988-01-21 Behringwerke Ag Pharmazeutische formulierung und verfahren zu deren herstellung
IL88076A (en) * 1987-10-28 1993-01-14 Nippon Shinyaku Co Ltd Fat emulsions as drug carriers
GB8822857D0 (en) * 1988-09-29 1988-11-02 Patralan Ltd Pharmaceutical formulations
GB9022788D0 (en) * 1990-10-19 1990-12-05 Cortecs Ltd Pharmaceutical formulations
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
GB9300875D0 (en) * 1993-01-18 1993-03-10 Ucb Sa Nanocapsule containing pharmaceutical compositions

Also Published As

Publication number Publication date
DK0808154T3 (da) 2001-04-30
CA2207304A1 (en) 1996-08-15
EP0808154B1 (de) 2000-12-20
ES2154806T3 (es) 2001-04-16
EP0808154A1 (de) 1997-11-26
PT808154E (pt) 2001-06-29
DE69611287T2 (de) 2001-08-09
ATE198148T1 (de) 2001-01-15
JPH10513200A (ja) 1998-12-15
AU4862796A (en) 1996-08-27
WO1996024332A1 (en) 1996-08-15
GR3035613T3 (en) 2001-06-29

Similar Documents

Publication Publication Date Title
DE69611287D1 (de) Formulierungen von verbindungen als nanopartikel dispergiert in verdaubaren ölen oder fettsäuren
DE69720787D1 (de) Pharmazeutische zubereitung enhaltend eicosapentaensäure und/oder stearidonsäure
EP0167825A3 (en) Lipid nano pellets as drug carriers for oral administration
CA2251414A1 (en) Stabilization of ascorbic acid, ascorbic acid derivatives and/or extracts containing ascorbic acid for topical use
ATE350013T1 (de) Nanopartikelzusammensetzungen enthaltend insulin
FI101384B1 (fi) Aktiiviaineen, joka on muu kuin lääkeaine, ja syklodekstriinin inkluusiokompleksi käytettäväksi kiinteässä kulutustuotekoostumuksessa
IE910050A1 (en) EFA compositions and therapy
DE69831511D1 (de) Mikropartikel zum transport von arzneistoffen durch die schleimhaut und die blut-hirn-schranke
NO964433L (no) Farmasöytiske preparater på basis av derivater av taxanklassen
DE3669106D1 (de) Pharmazeutische zusammensetzungen mit gehalt an flavanolignanen und phospholipiden als wirkstoffe.
ATE292455T1 (de) Fettlösliche vitamine enthaltende zusammensetzungen
ATE101036T1 (de) Aktivitaetspotenziator gegen krebs.
ZA971134B (en) Multifunctional fat absorption and blood cholesterol reducing formulation.
GR3002216T3 (en) Cosmetic product, particularly a skin hydratation product
KR910009267A (ko) 우울증의 치료방법
ATE110274T1 (de) Mittel zur verbesserung spezifischer eigenschaften des blutes.
FI946057A (fi) Paikalliseen käyttöön tarkoitettu valmiste
JP2004196665A (ja) スティギングを抑制した化粧料
JP2004196665A5 (de)
KR940003570A (ko) 개량된 방향제 조성물
KR950031082A (ko) 우르소데옥시콜린산의 신규한 유도체와 이를 포함하는 제약학적 성분물
KR900700086A (ko) 뇌기능 개선약
MX9604984A (es) Composiciones farmaceuticas a base de derivados de la clase de los taxanos.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee