GR3035613T3 - Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids - Google Patents

Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids

Info

Publication number
GR3035613T3
GR3035613T3 GR20010400459T GR20010400459T GR3035613T3 GR 3035613 T3 GR3035613 T3 GR 3035613T3 GR 20010400459 T GR20010400459 T GR 20010400459T GR 20010400459 T GR20010400459 T GR 20010400459T GR 3035613 T3 GR3035613 T3 GR 3035613T3
Authority
GR
Greece
Prior art keywords
formulations
compounds
fatty acids
digestible oils
nanoparticulate dispersions
Prior art date
Application number
GR20010400459T
Other languages
English (en)
Inventor
W Mark Eickhoff
Karl R Mueller
David A Engers
Original Assignee
Nanosystems Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/384,057 external-priority patent/US5571536A/en
Priority claimed from US08/388,088 external-priority patent/US5560931A/en
Application filed by Nanosystems Llc filed Critical Nanosystems Llc
Publication of GR3035613T3 publication Critical patent/GR3035613T3/el

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
GR20010400459T 1995-02-06 2001-03-20 Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids GR3035613T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/384,057 US5571536A (en) 1995-02-06 1995-02-06 Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids
US08/388,088 US5560931A (en) 1995-02-14 1995-02-14 Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids
PCT/US1996/001433 WO1996024332A1 (en) 1995-02-06 1996-01-31 Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids

Publications (1)

Publication Number Publication Date
GR3035613T3 true GR3035613T3 (en) 2001-06-29

Family

ID=27010448

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010400459T GR3035613T3 (en) 1995-02-06 2001-03-20 Formulations of compounds as nanoparticulate dispersions in digestible oils or fatty acids

Country Status (11)

Country Link
EP (1) EP0808154B1 (el)
JP (1) JPH10513200A (el)
AT (1) ATE198148T1 (el)
AU (1) AU4862796A (el)
CA (1) CA2207304A1 (el)
DE (1) DE69611287T2 (el)
DK (1) DK0808154T3 (el)
ES (1) ES2154806T3 (el)
GR (1) GR3035613T3 (el)
PT (1) PT808154E (el)
WO (1) WO1996024332A1 (el)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1009856A5 (fr) 1995-07-14 1997-10-07 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule.
US6045829A (en) * 1997-02-13 2000-04-04 Elan Pharma International Limited Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers
ES2257041T3 (es) * 1998-03-30 2006-07-16 Jagotec Ag Composicion y metodo para preparar microparticulas de substancias insolubles en agua.
US6337092B1 (en) 1998-03-30 2002-01-08 Rtp Pharma Inc. Composition and method of preparing microparticles of water-insoluble substances
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US20050048126A1 (en) 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
US7037528B2 (en) 2000-12-22 2006-05-02 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
CA2461349C (en) 2001-09-26 2011-11-29 Baxter International Inc. Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
BRPI0917771A2 (pt) * 2008-12-18 2015-08-04 Basf Se Dispersão aquosa, metodo de preparo da disperção, composição sólida, uso de um anfifílico, uso da dispersão e semente

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2714065A1 (de) * 1977-03-30 1978-10-12 Boehringer Mannheim Gmbh Instillationszubereitung
DE3623376A1 (de) * 1986-07-11 1988-01-21 Behringwerke Ag Pharmazeutische formulierung und verfahren zu deren herstellung
IL88076A (en) * 1987-10-28 1993-01-14 Nippon Shinyaku Co Ltd Fat emulsions as drug carriers
GB8822857D0 (en) * 1988-09-29 1988-11-02 Patralan Ltd Pharmaceutical formulations
GB9022788D0 (en) * 1990-10-19 1990-12-05 Cortecs Ltd Pharmaceutical formulations
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
GB9300875D0 (en) * 1993-01-18 1993-03-10 Ucb Sa Nanocapsule containing pharmaceutical compositions

Also Published As

Publication number Publication date
DE69611287T2 (de) 2001-08-09
EP0808154A1 (en) 1997-11-26
JPH10513200A (ja) 1998-12-15
CA2207304A1 (en) 1996-08-15
PT808154E (pt) 2001-06-29
WO1996024332A1 (en) 1996-08-15
ES2154806T3 (es) 2001-04-16
ATE198148T1 (de) 2001-01-15
DE69611287D1 (de) 2001-01-25
DK0808154T3 (da) 2001-04-30
EP0808154B1 (en) 2000-12-20
AU4862796A (en) 1996-08-27

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Legal Events

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ML Lapse due to non-payment of fees