DE69601026T2 - Verwendung eines Antagonisten von TNF-alpha zur Behandlung von Hautrötungen neurogenen Ursprungs - Google Patents
Verwendung eines Antagonisten von TNF-alpha zur Behandlung von Hautrötungen neurogenen UrsprungsInfo
- Publication number
- DE69601026T2 DE69601026T2 DE69601026T DE69601026T DE69601026T2 DE 69601026 T2 DE69601026 T2 DE 69601026T2 DE 69601026 T DE69601026 T DE 69601026T DE 69601026 T DE69601026 T DE 69601026T DE 69601026 T2 DE69601026 T2 DE 69601026T2
- Authority
- DE
- Germany
- Prior art keywords
- tnf
- treat skin
- skin redness
- alpha antagonist
- neurogenic origin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9513729A FR2741262B1 (fr) | 1995-11-20 | 1995-11-20 | Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69601026D1 DE69601026D1 (de) | 1999-01-07 |
DE69601026T2 true DE69601026T2 (de) | 1999-04-15 |
Family
ID=9484725
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69601026T Revoked DE69601026T2 (de) | 1995-11-20 | 1996-10-28 | Verwendung eines Antagonisten von TNF-alpha zur Behandlung von Hautrötungen neurogenen Ursprungs |
Country Status (12)
Country | Link |
---|---|
US (1) | US5895649A (de) |
EP (1) | EP0774250B1 (de) |
JP (1) | JPH11501665A (de) |
KR (1) | KR19990067052A (de) |
CN (1) | CN1116869C (de) |
AR (1) | AR004326A1 (de) |
AT (1) | ATE173620T1 (de) |
CA (1) | CA2235038C (de) |
DE (1) | DE69601026T2 (de) |
ES (1) | ES2127613T3 (de) |
FR (1) | FR2741262B1 (de) |
WO (1) | WO1997018799A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6685965B1 (en) * | 1997-10-22 | 2004-02-03 | Industria E Comercio De Cosmeticos Natura Ltda. | Process for stabilizing levogyre ascorbic acid (laa), a stable aqueous laa composition, a process for preparing a stable topical solution, an emulsion, a vitamin product, and a method for cosmetic, pharmaceutical or nutritional treatment |
MXPA01011613A (es) | 1999-05-14 | 2003-10-14 | Nereus Pharmaceuticals Inc | Nuevos moduladores de interleucina-1 y factor-alfa de necrosis tumoral, sistesis de dichos moduladores y metodos de utilizar dichos moduladores. |
WO2002089743A2 (en) * | 2001-05-09 | 2002-11-14 | The Regents Of The University Of Michigan | Use of compositions for treating rosacea |
US6723755B2 (en) | 2002-06-12 | 2004-04-20 | Piotr Chomczynski | Method of treating rosacea |
WO2004050683A2 (en) * | 2002-12-02 | 2004-06-17 | Abgenix, Inc. | Antibodies directed to tumor necrosis factor and uses thereof |
US20050147570A1 (en) * | 2004-01-06 | 2005-07-07 | Nordsiek Michael T. | Methods of administering diclofenac compositions for treating photodamaged skin, rosacea and/or acne |
US20060177445A1 (en) * | 2004-08-16 | 2006-08-10 | Boris Skurkovich | Treatment of inflammatory skin diseases |
US7812057B2 (en) * | 2004-08-25 | 2010-10-12 | Molecular Research Center, Inc. | Cosmetic compositions |
CA2613366A1 (en) | 2005-07-21 | 2007-02-08 | Nereus Pharmaceuticals, Inc. | Interleukin-1 and tumor necrosis factor-a modulators; syntheses of such modulators and methods of using such modulators |
FR2918884B1 (fr) * | 2007-07-17 | 2010-01-15 | Oreal | Utilisation d'extraits bacteriens cultives sur eau thermale comme agent anti-rougeur |
CA2727710C (en) * | 2008-06-11 | 2016-11-01 | Biochemics, Inc. | Control of blood vessel physiology to treat skin disorders |
CA2726726A1 (en) | 2008-09-10 | 2010-03-18 | Thrubit B.V. | Ibuprofen for topical administration |
BRPI0914192A2 (pt) | 2008-09-22 | 2015-11-03 | Biochemics Inc | distribuição transdérmica de fármaco usando um osmólito e agente vasoativo |
BRPI0921959A2 (pt) | 2008-12-04 | 2017-05-30 | Biochemics Inc | métodos e composições para remoção de tatuagem |
EP2430157B1 (de) * | 2010-05-27 | 2013-05-08 | Kenichiro Hasumi | Antigenpeptid und verwendung davon |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5921656A (ja) | 1982-07-28 | 1984-02-03 | Takeda Chem Ind Ltd | ポリペプチド誘導体 |
US4472305A (en) | 1983-05-17 | 1984-09-18 | Sterling Drug Inc. | Hexapeptide amides |
US4839465A (en) | 1987-01-20 | 1989-06-13 | Sterling Drug Inc. | Di-(D-tryptophyl and/or tetrahydropyridoindolylcarbonyl)-containing peptide amides and process for preparation thereof |
GB8807921D0 (en) | 1988-04-05 | 1988-05-05 | Fujisawa Pharmaceutical Co | Ws-9326 & its derivatives |
US5187156A (en) | 1988-03-16 | 1993-02-16 | Fujisawa Pharmaceutical Co., Ltd. | Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same |
GB8807246D0 (en) | 1988-03-25 | 1988-04-27 | Merck Sharp & Dohme | Therapeutic agents |
EP0360390A1 (de) | 1988-07-25 | 1990-03-28 | Glaxo Group Limited | Spirolactamderivate |
MX18467A (es) | 1988-11-23 | 1993-07-01 | Pfizer | Agentes terapeuticos de quinuclidinas |
US5164372A (en) | 1989-04-28 | 1992-11-17 | Fujisawa Pharmaceutical Company, Ltd. | Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same |
FR2654726B1 (fr) | 1989-11-23 | 1992-02-14 | Rhone Poulenc Sante | Nouveaux derives de l'isoindolone et leur preparation. |
FR2654725B1 (fr) | 1989-11-23 | 1992-02-14 | Rhone Poulenc Sante | Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent. |
GB8929070D0 (en) | 1989-12-22 | 1990-02-28 | Fujisawa Pharmaceutical Co | Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same |
US5232929A (en) | 1990-11-28 | 1993-08-03 | Pfizer Inc. | 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use |
WO1991009844A1 (en) | 1990-01-04 | 1991-07-11 | Pfizer Inc. | Substance p antagonists |
EP0515681A4 (en) | 1990-02-15 | 1993-12-29 | Fujisawa Pharmaceutical Co., Ltd. | Peptide compound |
PL169187B1 (pl) | 1990-05-31 | 1996-06-28 | Pfizer | Sposób wytwarzania podstawionych piperydyn PL PL PL |
DK0532527T3 (da) | 1990-06-01 | 1995-01-02 | Pfizer | 3-amino-2-arylquinuclidiner, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende disse |
EP0498069B1 (de) | 1990-12-21 | 1995-10-25 | Fujisawa Pharmaceutical Co., Ltd. | Neue Verwendung von Peptidderivat |
WO1992012151A1 (en) | 1991-01-10 | 1992-07-23 | Pfizer Inc. | N-alkyl quinuclidinium salts as substance p antagonists |
ATE154354T1 (de) | 1991-02-11 | 1997-06-15 | Merck Sharp & Dohme | Azabicyclische verbindungen, diese enthaltende pharmazeutische zubereitungen und ihre therapeutische verwendung |
DK0573522T3 (da) | 1991-03-01 | 1995-03-06 | Pfizer | 1-Azabicyclo(3,2,2)nonan-3-aminderivater |
RU2105001C1 (ru) | 1991-03-26 | 1998-02-20 | Пфайзер Инк. | Способ получения замещенных 3-аминопиперидинов |
FR2677361A1 (fr) | 1991-06-04 | 1992-12-11 | Adir | Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
FR2676447B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveaux derives du thiopyranopyrrole et leur preparation. |
FR2676443B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveaux derives de perhydroisoindole et leur preparation. |
FR2676442B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent. |
FR2676446B1 (fr) | 1991-05-17 | 1993-08-06 | Rhone Poulenc Rorer Sa | Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent. |
AU658898B2 (en) | 1991-05-22 | 1995-05-04 | Pfizer Inc. | Substituted 3-aminoquinuclidines |
GB9113219D0 (en) | 1991-06-19 | 1991-08-07 | Fujisawa Pharmaceutical Co | Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same |
RU2114848C1 (ru) | 1991-06-20 | 1998-07-10 | Пфайзер Инк. | Фторалкоксибензиламинные производные азотсодержащих гетероциклов, фармацевтическая композиция, способ ингибирования действия вещества р у млекопитающих |
TW202432B (de) | 1991-06-21 | 1993-03-21 | Pfizer | |
US5288730A (en) | 1991-06-24 | 1994-02-22 | Merck Sharp & Dohme Limited | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy |
CA2110514A1 (en) | 1991-07-05 | 1993-01-21 | Raymond Baker | Aromatic compounds, pharmaceutical compositions containing them and their use in therapy |
US5495047A (en) | 1991-07-10 | 1996-02-27 | Merck, Sharp & Dohme (Ltd.) | Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy |
MY110227A (en) | 1991-08-12 | 1998-03-31 | Ciba Geigy Ag | 1-acylpiperindine compounds. |
US5459270A (en) | 1991-08-20 | 1995-10-17 | Merck Sharp & Dohme Limited | Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them |
DK0607164T3 (da) | 1991-09-26 | 2002-06-17 | Pfizer | Kondenserede tricykliske nitrogenholdige heterocykliske forbindelser som substans P-receptorantagonister |
JP2553020B2 (ja) | 1991-11-07 | 1996-11-13 | 吉富製薬株式会社 | キヌクリジン化合物およびその医薬用途 |
EP0545478A1 (de) | 1991-12-03 | 1993-06-09 | MERCK SHARP & DOHME LTD. | Heterocyclische Verbindungen als Tachykininantagoniste |
JP2656699B2 (ja) | 1992-10-21 | 1997-09-24 | ファイザー製薬株式会社 | 置換ベンジルアミノキヌクリジン |
FR2719474B1 (fr) * | 1994-05-05 | 1996-05-31 | Oreal | Utilisation d'un antagoniste de substance P dans une composition cosmétique et composition obtenue. |
-
1995
- 1995-11-20 FR FR9513729A patent/FR2741262B1/fr not_active Expired - Lifetime
-
1996
- 1996-10-28 WO PCT/FR1996/001688 patent/WO1997018799A1/fr not_active Application Discontinuation
- 1996-10-28 DE DE69601026T patent/DE69601026T2/de not_active Revoked
- 1996-10-28 ES ES96402291T patent/ES2127613T3/es not_active Expired - Lifetime
- 1996-10-28 KR KR1019980702989A patent/KR19990067052A/ko not_active Application Discontinuation
- 1996-10-28 AT AT96402291T patent/ATE173620T1/de not_active IP Right Cessation
- 1996-10-28 EP EP96402291A patent/EP0774250B1/de not_active Revoked
- 1996-10-28 CN CN96198450A patent/CN1116869C/zh not_active Expired - Lifetime
- 1996-10-28 CA CA002235038A patent/CA2235038C/fr not_active Expired - Lifetime
- 1996-10-28 JP JP9519429A patent/JPH11501665A/ja active Pending
- 1996-11-18 AR ARP960105222A patent/AR004326A1/es unknown
- 1996-11-20 US US08/752,551 patent/US5895649A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH11501665A (ja) | 1999-02-09 |
CA2235038C (fr) | 2004-12-14 |
US5895649A (en) | 1999-04-20 |
EP0774250B1 (de) | 1998-11-25 |
CN1116869C (zh) | 2003-08-06 |
EP0774250A1 (de) | 1997-05-21 |
AR004326A1 (es) | 1998-11-04 |
ES2127613T3 (es) | 1999-04-16 |
KR19990067052A (ko) | 1999-08-16 |
WO1997018799A1 (fr) | 1997-05-29 |
FR2741262B1 (fr) | 1999-03-05 |
CN1202822A (zh) | 1998-12-23 |
ATE173620T1 (de) | 1998-12-15 |
FR2741262A1 (fr) | 1997-05-23 |
CA2235038A1 (fr) | 1997-05-29 |
DE69601026D1 (de) | 1999-01-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8331 | Complete revocation |