DE69533777D1 - Mit retenoid x-rezeptor interagierende polypeptide und verwandte moleküle und verfahren - Google Patents

Mit retenoid x-rezeptor interagierende polypeptide und verwandte moleküle und verfahren

Info

Publication number
DE69533777D1
DE69533777D1 DE69533777T DE69533777T DE69533777D1 DE 69533777 D1 DE69533777 D1 DE 69533777D1 DE 69533777 T DE69533777 T DE 69533777T DE 69533777 T DE69533777 T DE 69533777T DE 69533777 D1 DE69533777 D1 DE 69533777D1
Authority
DE
Germany
Prior art keywords
receptor
retenoid
polypeptides
related molecules
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69533777T
Other languages
English (en)
Other versions
DE69533777T2 (de
Inventor
David Moore
Wongi Seol
Hueng-Sik Choi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Application granted granted Critical
Publication of DE69533777D1 publication Critical patent/DE69533777D1/de
Publication of DE69533777T2 publication Critical patent/DE69533777T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69533777T 1995-01-13 1995-12-08 Mit retenoid x-rezeptor interagierende polypeptide und verwandte moleküle und verfahren Expired - Lifetime DE69533777T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/372,652 US5932699A (en) 1995-01-13 1995-01-13 Retinoid X receptor-interacting polypeptides
US372652 1995-01-13
PCT/US1995/016311 WO1996021677A1 (en) 1995-01-13 1995-12-08 Retinoid x receptor-interacting polypeptides and related molecules and methods

Publications (2)

Publication Number Publication Date
DE69533777D1 true DE69533777D1 (de) 2004-12-23
DE69533777T2 DE69533777T2 (de) 2005-11-10

Family

ID=23469101

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69533777T Expired - Lifetime DE69533777T2 (de) 1995-01-13 1995-12-08 Mit retenoid x-rezeptor interagierende polypeptide und verwandte moleküle und verfahren

Country Status (6)

Country Link
US (3) US5932699A (de)
EP (1) EP0801657B1 (de)
JP (2) JPH11502402A (de)
AT (1) ATE282696T1 (de)
DE (1) DE69533777T2 (de)
WO (1) WO1996021677A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5932699A (en) * 1995-01-13 1999-08-03 The General Hospital Corporation Retinoid X receptor-interacting polypeptides
US6005086A (en) * 1995-01-13 1999-12-21 The Salk Institute For Biological Studies Farnesoid activated receptor polypeptides, and nucleic acid encoding the same
US6350583B1 (en) * 1997-09-09 2002-02-26 Abbott Laboratories Reagents and methods useful for detecting diseases of the prostate
AU7330400A (en) * 1999-08-16 2001-03-13 Human Genome Sciences, Inc. Retinoid receptor interacting polynucleotides, polypeptides, and antibodies
WO2002022817A2 (en) * 2000-09-16 2002-03-21 Lion Bioscience Ag Nuclear receptor l66 and methods of use
WO2002066614A2 (en) 2001-02-20 2002-08-29 Rheogene Holdings, Inc. Chimeric retinoid x receptors and their use in a novel ecdysone receptor-based inducible gene expression system
AU2002306550B2 (en) 2001-02-20 2007-10-25 Intrexon Corporation Novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
US20030082682A1 (en) * 2001-03-30 2003-05-01 Bawagan Hinayana L. Polynucleotide and polypeptide sequence of RXR interacting protein, RB204
AU2002354930A1 (en) * 2001-07-17 2003-03-03 Smithkline Beecham Corporation Mouse farnesoid x receptor sequences for use in comparative pharmacology
US7365160B2 (en) * 2002-02-19 2008-04-29 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Mutated constitutively active nuclear orphan receptor
US20030170724A1 (en) * 2002-03-08 2003-09-11 Anderson David C. Methods of identifying target polypeptides
KR100492514B1 (ko) * 2002-05-03 2005-06-03 학교법인 포항공과대학교 레티노산에 의해 발현이 조절되는 재조합 리포터 유전자를가지는 형질전환 세포주 및 이를 이용한 레티노산유사물질 및 저해물질의 생물학적 검색방법
JP2004290193A (ja) * 2003-03-12 2004-10-21 Ishihara Sangyo Kaisha Ltd 細胞増殖、発生分化が改変された植物細胞及び植物体

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5071773A (en) * 1986-10-24 1991-12-10 The Salk Institute For Biological Studies Hormone receptor-related bioassays
US4981784A (en) * 1987-12-02 1991-01-01 The Salk Institute For Biological Studies Retinoic acid receptor method
JPH04504654A (ja) * 1988-12-23 1992-08-20 ザ　ソーク　インスティテュート　フォア　バイオロジカル　スタディーズ レセプターの転写抑制活性組成物および方法
AU7492291A (en) * 1990-02-26 1991-09-18 Board Of Trustees Of The Leland Stanford Junior University Identification and expression of insect steroid receptor dna sequences
WO1995013373A1 (en) * 1993-11-10 1995-05-18 Arch Development Corporation Ubiquitous nuclear receptor: compositions and methods
GB9416536D0 (en) * 1994-08-16 1994-10-12 Karobio Ab Orphan receptor
WO1996009324A1 (fr) * 1994-09-21 1996-03-28 Cancer Institute Proteine ecdn et adn codant cette proteine
US5679518A (en) * 1994-10-27 1997-10-21 Merck & Co., Inc. Method for finding transcription activators of the NER steroid hormone receptor
US5932699A (en) * 1995-01-13 1999-08-03 The General Hospital Corporation Retinoid X receptor-interacting polypeptides

Also Published As

Publication number Publication date
DE69533777T2 (de) 2005-11-10
JP2006068010A (ja) 2006-03-16
US5932699A (en) 1999-08-03
EP0801657B1 (de) 2004-11-17
WO1996021677A1 (en) 1996-07-18
EP0801657A1 (de) 1997-10-22
ATE282696T1 (de) 2004-12-15
US20060287503A1 (en) 2006-12-21
EP0801657A4 (de) 2000-12-06
JPH11502402A (ja) 1999-03-02
US7115711B1 (en) 2006-10-03

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