DE69533255D1 - ISOLIERTES p27 PROTEIN UND NUKLEINSÄURE DAFÜR KODIEREND - Google Patents

ISOLIERTES p27 PROTEIN UND NUKLEINSÄURE DAFÜR KODIEREND

Info

Publication number
DE69533255D1
DE69533255D1 DE69533255T DE69533255T DE69533255D1 DE 69533255 D1 DE69533255 D1 DE 69533255D1 DE 69533255 T DE69533255 T DE 69533255T DE 69533255 T DE69533255 T DE 69533255T DE 69533255 D1 DE69533255 D1 DE 69533255D1
Authority
DE
Germany
Prior art keywords
protein
subject invention
nucleic acid
isolated
cyclin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69533255T
Other languages
English (en)
Other versions
DE69533255T2 (de
Inventor
Joah Massague
James M Roberts
Andrew Koff
Kornelia Polyak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Memorial Sloan Kettering Cancer Center
Fred Hutchinson Cancer Center
Original Assignee
Sloan Kettering Institute for Cancer Research
Fred Hutchinson Cancer Research Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sloan Kettering Institute for Cancer Research, Fred Hutchinson Cancer Research Center filed Critical Sloan Kettering Institute for Cancer Research
Publication of DE69533255D1 publication Critical patent/DE69533255D1/de
Application granted granted Critical
Publication of DE69533255T2 publication Critical patent/DE69533255T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69533255T 1994-01-07 1995-01-09 ISOLIERTES p27 PROTEIN UND NUKLEINSÄURE DAFÜR KODIEREND Expired - Lifetime DE69533255T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17904594A 1994-01-07 1994-01-07
US179045 1994-01-07
US275983 1994-07-15
US08/275,983 US5688665A (en) 1994-01-07 1994-07-15 Isolated nucleic acid molecules encoding the p27 KIP-1 protein
PCT/US1995/000247 WO1995018824A1 (en) 1994-01-07 1995-01-09 ISOLATED p27 PROTEIN AND ITS ENCODING NUCLEIC ACID MOLECULES

Publications (2)

Publication Number Publication Date
DE69533255D1 true DE69533255D1 (de) 2004-08-19
DE69533255T2 DE69533255T2 (de) 2005-07-28

Family

ID=26874941

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69533255T Expired - Lifetime DE69533255T2 (de) 1994-01-07 1995-01-09 ISOLIERTES p27 PROTEIN UND NUKLEINSÄURE DAFÜR KODIEREND

Country Status (8)

Country Link
US (1) US5688665A (de)
EP (1) EP0749442B1 (de)
JP (1) JP4143119B2 (de)
AT (1) ATE271129T1 (de)
AU (1) AU699969B2 (de)
CA (1) CA2180570C (de)
DE (1) DE69533255T2 (de)
WO (1) WO1995018824A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6242575B1 (en) 1994-01-07 2001-06-05 Fred Hutchinson Institute For Cancer Research Antibodies for detecting p27 protein
US6355774B1 (en) 1994-01-07 2002-03-12 Fred Hutchinson Cancer Research Center Isolated p27 protein
US6316208B1 (en) * 1994-01-07 2001-11-13 Memorial Sloan-Kettering Cancer Center Methods for determining isolated p27 protein levels and uses thereof
AU2770695A (en) 1994-07-15 1996-02-16 Fred Hutchinson Cancer Research Center Isolated p27 protein and methods for its production and use
WO1996025507A2 (en) * 1995-02-17 1996-08-22 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Methods of preparation and use of recombinant adenoviral vectors
US7087582B1 (en) 1995-09-26 2006-08-08 Regents Of The University Of Michigan Combination for site-specifically transforming cells in vivo comprising a double-balloon catheter and nucleic acid comprising a gene encoding P21
US5863904A (en) 1995-09-26 1999-01-26 The University Of Michigan Methods for treating cancers and restenosis with P21
AU3483795A (en) * 1995-09-29 1997-04-28 Ciba-Geigy Ag Ring finger protein
JP2000503538A (ja) 1996-01-18 2000-03-28 フレッド ハッチンソン カンサー リサーチ センター 細胞周期を仲介する組成物および方法
ATE403744T1 (de) * 1997-05-15 2008-08-15 Univ Jefferson Bestimmung der vorhandenen mengen an cyclin- abhängigem kinase-inhibitor p27 als prognostischem faktor bei krebspatienten
US6177272B1 (en) 1997-07-21 2001-01-23 The Regents Of The University Of Michigan Method for treating vascular proliferative diseases with p27 and fusions thereof
JP4323716B2 (ja) * 1997-08-21 2009-09-02 トーマス・ジェファーソン・ユニバーシティ ｃｄｋ２キナーゼ活性のｐＲｂ２／ｐ１３０ペプチドインヒビター
US6972170B1 (en) * 1997-12-01 2005-12-06 Sloan-Kettering Institute For Cancer Research Markers for prostate cancer
AU1801499A (en) * 1997-12-01 1999-06-16 Sloan-Kettering Institute For Cancer Research Uses of p27 in prostate cancer
US6479487B1 (en) * 1998-02-26 2002-11-12 Aventis Pharmaceuticals Inc. 6, 9-disubstituted 2-[trans-(4-aminocyclohexyl)amino] purines
US6413974B1 (en) * 1998-02-26 2002-07-02 Aventis Pharmaceuticals Inc. 6,9,-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines
US5973119A (en) * 1998-06-05 1999-10-26 Amgen Inc. Cyclin E genes and proteins
EP1087994A1 (de) * 1998-06-18 2001-04-04 Curagen Corporation Interaktion zwischen p27(kip1) und fkbp-12
US6589505B1 (en) 1999-01-29 2003-07-08 St. Jude Children's Research Hospital Cells that lack p19ink4d and p27kip1 activity and methods of use thereof
AU781259B2 (en) 1999-05-14 2005-05-12 Fred Hutchinson Cancer Research Center Methods for increasing plant cell proliferation by functionally inhibiting a plant cyclin inhibitor gene
WO2000077258A1 (en) * 1999-06-10 2000-12-21 Sloan-Kettering Institute For Cancer Research Markers for prostate cancer
AU783935B2 (en) * 1999-06-18 2006-01-05 Indiana University Research And Technology Corporation Cardiomyocytes with enhanced proliferative potential, and methods for preparing and using same
WO2002076195A1 (en) * 2001-03-26 2002-10-03 University Of South Florida Ras p27 animal models and uses thereof
GB0117600D0 (en) * 2001-07-19 2001-09-12 Trikon Holdings Ltd Semiconductor structure
US7601299B2 (en) * 2004-06-18 2009-10-13 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US20080053911A1 (en) * 2006-08-30 2008-03-06 Qiagen Gmbh Separation of an organic phase from a mixture comprising organic and aqueous phases by solid phase systems
PT3104939T (pt) 2014-02-10 2024-07-17 Fred Hutchinson Cancer Center Tratamento de ataque cardíaco e lesão isquémica com iodeto de sódio

Also Published As

Publication number Publication date
ATE271129T1 (de) 2004-07-15
JPH09509311A (ja) 1997-09-22
AU699969B2 (en) 1998-12-17
US5688665A (en) 1997-11-18
WO1995018824A1 (en) 1995-07-13
CA2180570A1 (en) 1995-07-13
DE69533255T2 (de) 2005-07-28
EP0749442B1 (de) 2004-07-14
EP0749442A1 (de) 1996-12-27
JP4143119B2 (ja) 2008-09-03
EP0749442A4 (de) 2000-06-28
CA2180570C (en) 2002-03-26
AU1525195A (en) 1995-08-01

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