DE69532482D1 - Kombinationspräparat zur behandlung der parkinsonschen krankheit, das selektive nmda-antagonisten enthält - Google Patents

Kombinationspräparat zur behandlung der parkinsonschen krankheit, das selektive nmda-antagonisten enthält

Info

Publication number
DE69532482D1
DE69532482D1 DE69532482T DE69532482T DE69532482D1 DE 69532482 D1 DE69532482 D1 DE 69532482D1 DE 69532482 T DE69532482 T DE 69532482T DE 69532482 T DE69532482 T DE 69532482T DE 69532482 D1 DE69532482 D1 DE 69532482D1
Authority
DE
Germany
Prior art keywords
parkinson
combination
treatment
selective nmda
nmda antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69532482T
Other languages
English (en)
Other versions
DE69532482T2 (de
Inventor
L Chenard
S Menniti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE69532482D1 publication Critical patent/DE69532482D1/de
Publication of DE69532482T2 publication Critical patent/DE69532482T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G10—MUSICAL INSTRUMENTS; ACOUSTICS
    • G10H—ELECTROPHONIC MUSICAL INSTRUMENTS; INSTRUMENTS IN WHICH THE TONES ARE GENERATED BY ELECTROMECHANICAL MEANS OR ELECTRONIC GENERATORS, OR IN WHICH THE TONES ARE SYNTHESISED FROM A DATA STORE
    • G10H5/00—Instruments in which the tones are generated by means of electronic generators
    • G10H5/10—Instruments in which the tones are generated by means of electronic generators using generation of non-sinusoidal basic tones, e.g. saw-tooth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Multimedia (AREA)
  • Acoustics & Sound (AREA)
  • Physics & Mathematics (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Hydrogenated Pyridines (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
DE69532482T 1995-05-26 1995-05-26 Kombinationspräparat zur behandlung der parkinsonschen krankheit, das selektive nmda-antagonisten enthält Expired - Fee Related DE69532482T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IB1995/000398 WO1996037226A2 (en) 1995-05-26 1995-05-26 Combinations for the treatment of parkinsonism containing selective nmda antagonists
HU9601419A HUP9601419A3 (en) 1995-05-26 1996-05-24 Synergetic pharmaceutical compositions for treating parkinson-disease

Publications (2)

Publication Number Publication Date
DE69532482D1 true DE69532482D1 (de) 2004-02-26
DE69532482T2 DE69532482T2 (de) 2004-11-25

Family

ID=89994003

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69532482T Expired - Fee Related DE69532482T2 (de) 1995-05-26 1995-05-26 Kombinationspräparat zur behandlung der parkinsonschen krankheit, das selektive nmda-antagonisten enthält

Country Status (26)

Country Link
US (1) US6258827B1 (de)
EP (1) EP0828513B1 (de)
JP (1) JPH11505828A (de)
CN (1) CN1159325A (de)
AT (1) ATE258067T1 (de)
AU (1) AU696258B2 (de)
BR (1) BR9602485A (de)
CA (1) CA2219911C (de)
CO (1) CO4700422A1 (de)
CZ (1) CZ283979B6 (de)
DE (1) DE69532482T2 (de)
DK (1) DK0828513T3 (de)
ES (1) ES2211904T3 (de)
FI (1) FI974323A (de)
HU (1) HUP9601419A3 (de)
IL (1) IL118328A (de)
MX (1) MX9709112A (de)
NO (1) NO962130L (de)
NZ (1) NZ286656A (de)
PL (1) PL314413A1 (de)
PT (1) PT828513E (de)
RU (1) RU2176145C2 (de)
SG (1) SG45479A1 (de)
TR (1) TR199600436A2 (de)
TW (1) TW470740B (de)
WO (1) WO1996037226A2 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2321190B (en) * 1997-01-16 2000-09-20 Britannia Pharmaceuticals Ltd Pharmaceutical composition
HUP0004900A3 (en) * 1997-10-24 2002-03-28 Warner Lambert Co Pharmaceutical compositions for treating disease-related or drug-induced dyskinesias containing piperidine derivatives as nmda receptor antagonist as active ingredient
US6432976B1 (en) 1999-10-29 2002-08-13 Merck & Co., Inc. 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists
US6495561B2 (en) 1999-10-29 2002-12-17 Merck & Co., Inc. 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
US6362196B1 (en) 1999-10-29 2002-03-26 Merck & Co., Inc. Method to treat pain utilizing benzimidazole NMDA/NR2B antagonists
US6291499B1 (en) 1999-10-29 2001-09-18 Merck & Co., Inc. 2-cyclohexyl benzimidazole NMDA/NR2B antagonists
US6316474B1 (en) 1999-10-29 2001-11-13 Merck & Co., Inc. 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists
US6380205B1 (en) 1999-10-29 2002-04-30 Merck & Co., Inc. 2-cyclohexyl quinazoline NMDA/NR2B antagonists
US6489477B1 (en) 1999-10-29 2002-12-03 Merck & Co., Inc. 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
EP1186303A3 (de) * 2000-09-06 2003-12-10 Pfizer Products Inc. Ein Neutrophilhemmender Faktor und ein selektive NMDA-NR2B Rezeptor Antagonisten enthaltende Kombinationspräparate zur Behandlung von Schlaganfällen und traumatischen Gehirnschäden
ATE324371T1 (de) 2001-02-23 2006-05-15 Merck & Co Inc N-substituierte heterocyclische nichtaryl- nmda/nr2b-antagonisten
US20020165246A1 (en) * 2001-03-05 2002-11-07 Andrew Holman Administration of sleep restorative agents
EP1436258A4 (de) * 2001-03-08 2005-03-23 Univ Emory Ph-wert-abhängige nmda-rezeptorantagonisten
EP1390034A4 (de) 2001-04-03 2005-07-13 Merck & Co Inc N-substituierte nonaryl-heterocyclo amidyl-nmda/nr2b-antagonisten
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
DE10142176A1 (de) * 2001-08-29 2003-03-27 Eucro Europe Contract Res Gmbh Verwendung einer Kombination aus ß-adrenergen Agonisten und NDMA-Antagonisten
WO2003062235A1 (en) * 2002-01-17 2003-07-31 Eli Lilly And Company Modulators of acetylcholine receptors
US6743921B2 (en) * 2002-01-24 2004-06-01 Dsm Catalytica Pharmaceuticals, Inc. Process for the preparation of nonracemic syn-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenyl-piperidin-1-yl)-1-propanol compounds
ES2297233T3 (es) * 2002-10-08 2008-05-01 Allergan, Inc. Uso de brimonidina en el tratamiento de demencia y enfermedad de parkinson.
AR044007A1 (es) 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
US7763588B2 (en) * 2003-06-13 2010-07-27 The Salk Institute For Biological Studies Method for increasing cognitive function and neurogenesis
WO2005025561A1 (en) * 2003-09-04 2005-03-24 Synergia Pharma, Inc. Compositions and methods for orthostatic intolerance
CA2537765A1 (en) * 2003-09-04 2005-03-17 Board Of Regents, The University Of Texas System Methods and compositions for the prevention and treatment of genitourinary disorders, including pre-term labor and leiomyomas
EP1588704A1 (de) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamidderivate zur Behandlung des Restless-Leg-Syndroms und der Suchterkrankungen
WO2006042249A2 (en) * 2004-10-08 2006-04-20 Neuromolecular Pharmaceuticals, Inc. Methods and compositions for treating migraine pain
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
JP2008526923A (ja) * 2005-01-13 2008-07-24 ノイロサーチ アクティーゼルスカブ 新規８−置換８−アザ−ビシクロ［３．２．１］オクタン誘導体及びモノアミン神経伝達物質再取り込み阻害剤としてのそれらの使用
DK1874282T3 (da) * 2005-04-06 2010-10-25 Adamas Pharmaceuticals Inc Fremgangsmåder og præparater til behandling af CNS lidelser
US20070118044A1 (en) * 2005-07-18 2007-05-24 Mega Elektroniikka Oy Method and device for identifying; measuring and analyzing abnormal neurological responses
EP1870097A1 (de) * 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamidederivate zur Behandlung von kognitiven Störungen
RU2324492C1 (ru) * 2006-12-04 2008-05-20 Общество с ограниченной ответственностью "Березовый мир" Средство для профилактики и лечения болезни паркинсона
NZ582917A (en) 2007-06-29 2013-01-25 Univ Emory Nmda receptor antagonists for neuroprotection
CN102105169B (zh) * 2008-06-06 2014-09-10 图必制药公司 用于治疗帕金森病的药物组合物
US8648198B2 (en) 2011-01-19 2014-02-11 Cold Spring Harbor Laboratory Phenylethanolamine-based NMDA receptor antagonists
WO2013156614A1 (en) * 2012-04-20 2013-10-24 Ucb Pharma S.A. Methods for treating parkinson's disease
MX2016011837A (es) 2014-03-13 2017-04-27 Neuroderm Ltd Composiciones de inhibidores de la dopa decarboxilasa.
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5272160A (en) 1989-05-17 1993-12-21 Pfizer Inc 2-piperidino-1-alkanol derivatives as antiischemic agents
WO1991012005A1 (en) 1990-02-06 1991-08-22 Pfizer Inc. Neuroprotective 3-piperidino-4-hydroxychroman derivatives and analogs
CZ390792A3 (en) 1991-04-18 1994-04-13 Pfizer Precursors of medicaments based on esters of phenolic 2-piperidino-1-alkanols, process of their preparation, intermediates and use
DE4118740A1 (de) 1991-06-05 1992-12-10 Schering Ag Neue kombinationspraeparate zur behandlung des morbus parkinson

Also Published As

Publication number Publication date
ATE258067T1 (de) 2004-02-15
RU2176145C2 (ru) 2001-11-27
SG45479A1 (en) 1998-01-16
CA2219911C (en) 2004-07-27
HUP9601419A2 (en) 1997-09-29
CA2219911A1 (en) 1996-11-28
TR199600436A2 (tr) 1996-12-21
TW470740B (en) 2002-01-01
CZ283979B6 (cs) 1998-07-15
JPH11505828A (ja) 1999-05-25
MX9709112A (es) 1998-02-28
EP0828513A2 (de) 1998-03-18
CZ152496A3 (cs) 1998-04-15
DE69532482T2 (de) 2004-11-25
US6258827B1 (en) 2001-07-10
FI974323A0 (fi) 1997-11-25
HU9601419D0 (en) 1996-07-29
NZ286656A (en) 2001-03-30
AU5451996A (en) 1996-12-05
PL314413A1 (en) 1996-12-09
DK0828513T3 (da) 2004-04-13
WO1996037226A2 (en) 1996-11-28
NO962130L (no) 1996-11-27
WO1996037226A3 (en) 1996-12-27
FI974323A (fi) 1997-11-25
CO4700422A1 (es) 1998-12-29
CN1159325A (zh) 1997-09-17
ES2211904T3 (es) 2004-07-16
NO962130D0 (no) 1996-05-24
IL118328A (en) 2001-06-14
AU696258B2 (en) 1998-09-03
PT828513E (pt) 2004-05-31
EP0828513B1 (de) 2004-01-21
BR9602485A (pt) 1998-04-22
HUP9601419A3 (en) 1998-01-28
IL118328A0 (en) 1996-09-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee