DE69532443D1 - Fluorkohlenwasserstoff-treibgas enthaltende medizinische aerosole - Google Patents

Fluorkohlenwasserstoff-treibgas enthaltende medizinische aerosole

Info

Publication number
DE69532443D1
DE69532443D1 DE69532443T DE69532443T DE69532443D1 DE 69532443 D1 DE69532443 D1 DE 69532443D1 DE 69532443 T DE69532443 T DE 69532443T DE 69532443 T DE69532443 T DE 69532443T DE 69532443 D1 DE69532443 D1 DE 69532443D1
Authority
DE
Germany
Prior art keywords
hfc
fluorocoline
fuel gas
aerosols containing
polyethylene glycol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69532443T
Other languages
English (en)
Other versions
DE69532443T2 (de
Inventor
Peter Byron
Frank Blondino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Virginia Commonwealth University
Virginia Commonwealth University Intellectual Property Foundation
Original Assignee
Virginia Commonwealth University
Virginia Commonwealth University Intellectual Property Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virginia Commonwealth University, Virginia Commonwealth University Intellectual Property Foundation filed Critical Virginia Commonwealth University
Publication of DE69532443D1 publication Critical patent/DE69532443D1/de
Application granted granted Critical
Publication of DE69532443T2 publication Critical patent/DE69532443T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69532443T 1994-04-11 1995-04-11 Fluorkohlenwasserstoff-treibgas enthaltende medizinische aerosole Expired - Fee Related DE69532443T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US226041 1994-04-11
US08/226,041 US5508023A (en) 1994-04-11 1994-04-11 Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in metered dose inhaler formulations which use HFC-227 propellant
PCT/US1995/004528 WO1995027476A1 (en) 1994-04-11 1995-04-11 Hydrofluorocarbon propellant containing medicinal aerosols

Publications (2)

Publication Number Publication Date
DE69532443D1 true DE69532443D1 (de) 2004-02-19
DE69532443T2 DE69532443T2 (de) 2004-12-02

Family

ID=22847320

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69532443T Expired - Fee Related DE69532443T2 (de) 1994-04-11 1995-04-11 Fluorkohlenwasserstoff-treibgas enthaltende medizinische aerosole

Country Status (10)

Country Link
US (1) US5508023A (de)
EP (1) EP0755247B1 (de)
JP (1) JPH10502906A (de)
AT (1) ATE257695T1 (de)
CA (1) CA2187447C (de)
DE (1) DE69532443T2 (de)
DK (1) DK0755247T3 (de)
ES (1) ES2217277T3 (de)
PT (1) PT755247E (de)
WO (1) WO1995027476A1 (de)

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CA2361954C (en) * 1995-04-14 2003-07-08 Smithkline Beecham Corporation Metered dose inhaler for albuterol
EE04004B1 (et) 1995-04-14 2003-04-15 Glaxo Wellcome Inc. Flutikasoonpropionaati doseeriv inhalaator
BR9604977A (pt) 1995-04-14 1998-06-09 Glaxo Wellcome Inc Inalador de dose medida sistema inalador de dose medida e uso do mesmo
US5840213A (en) * 1995-04-28 1998-11-24 Great Lakes Chemical Corporation Uses of heptafluoropropane
AUPN814496A0 (en) 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
GB9610341D0 (en) * 1996-05-17 1996-07-24 Andaris Ltd Formulation for inhalation
JP4079469B2 (ja) * 1996-06-25 2008-04-23 出光興産株式会社 冷凍機油組成物
GB9620187D0 (en) * 1996-09-27 1996-11-13 Minnesota Mining & Mfg Medicinal aerosol formulations
US6039932A (en) * 1996-09-27 2000-03-21 3M Innovative Properties Company Medicinal inhalation aerosol formulations containing budesonide
US6413496B1 (en) 1996-12-04 2002-07-02 Biogland Ireland (R&D) Limited Pharmaceutical compositions and devices for their administration
GB2326334A (en) * 1997-06-13 1998-12-23 Chiesi Farma Spa Pharmaceutical aerosol compositions
US6197280B1 (en) * 1997-09-09 2001-03-06 Bioglan Laboratories Limited Pharmaceutical compositions and devices for their administration
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US20030103906A1 (en) * 1997-10-14 2003-06-05 Smithkline Beecham Corporation Metered dose inhaler having internal surfaces coated with fluorocarbon polymer
US6451285B2 (en) 1998-06-19 2002-09-17 Baker Norton Pharmaceuticals, Inc. Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant
TW465235B (en) 1998-09-17 2001-11-21 United Video Properties Inc Electronic program guide with digital storage
US6290930B1 (en) * 1998-12-18 2001-09-18 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes and budesonide
US7648696B2 (en) * 1999-08-20 2010-01-19 Unimed Pharmaceuticals, Llc Composition for inhalation comprising delta-9-tetrahydrocannabinol in a semiaqueous solvent
US6747058B1 (en) 1999-08-20 2004-06-08 Unimed Pharmaceuticals, Inc. Stable composition for inhalation therapy comprising delta-9-tetrahydrocannabinol and semiaqueous solvent therefor
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
US20030140920A1 (en) * 2001-10-26 2003-07-31 Dey L.P. Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma
JP2003221335A (ja) 2001-10-26 2003-08-05 Dey Lp 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法
US6702997B2 (en) 2001-10-26 2004-03-09 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
US20030203930A1 (en) * 2001-10-26 2003-10-30 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US20030191151A1 (en) * 2001-10-26 2003-10-09 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
ATE508735T1 (de) 2001-12-19 2011-05-15 Novartis Ag Pulmonale verabreichung von aminoglykosiden
EP1455764B1 (de) * 2001-12-21 2008-08-27 3M Innovative Properties Company Medizinische aerosolzusammensetzungen mit einer eine amid- und/oder estergruppe enthaltenden exzipientenverbindung
AU2002367032B8 (en) * 2001-12-21 2008-10-23 3M Innovative Properties Company Medicinal aerosol compositions with a functionalized polyethyleneglycol excipient
JP2005514437A (ja) * 2001-12-21 2005-05-19 スリーエム イノベイティブ プロパティズ カンパニー イオン対複合体を含む医薬用エアロゾル製剤
US7582284B2 (en) * 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
US7459146B2 (en) 2003-05-30 2008-12-02 3M Innovative Properties Company Stabilized aerosol dispersions
EP1663159A4 (de) * 2003-09-10 2010-06-09 Map Pharmaceuticals Inc Aerosol-formulierungen zur abgabe von dihydroergotamin an den systemischen kreislauf durch pulmonale inhalation
JP5087539B2 (ja) 2005-05-18 2012-12-05 ネクター セラピューティックス 気管支内治療のためのバルブ、デバイス、および方法
US7851419B2 (en) * 2005-09-12 2010-12-14 Nawaz Ahmad Substantially anhydrous sprayable personal lubricant
BRPI0616642A2 (pt) 2005-09-29 2011-06-28 Nektar Therapeutics formulações de antibióticos, doses unitárias, kits e métodos
US20070243262A1 (en) * 2005-12-21 2007-10-18 Hurley Kevin P Stable S-nitrosothiol formulations
US20070286814A1 (en) * 2006-06-12 2007-12-13 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
MX2009008582A (es) * 2007-02-11 2009-10-30 Map Pharmaceuticals Inc Metodo para la administracion terapeutica de dihidroergotamina para permitir un rapido alivio de la migraña mientras se minimiza el perfil de efectos secundarios.
US20110171141A1 (en) * 2009-06-26 2011-07-14 Kellerman Donald J Administration of dihydroergotamine mesylate particles using a metered dose inhaler

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GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5118494A (en) * 1990-03-23 1992-06-02 Minnesota Mining And Manufacturing Company Use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
WO1992000062A1 (en) * 1990-06-27 1992-01-09 Minnesota Mining And Manufacturing Company The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
WO1992000107A1 (en) * 1990-06-28 1992-01-09 Glaxo Inc. Aerosol drug formulations
ATE134509T1 (de) * 1991-06-10 1996-03-15 Schering Corp Fluorchlorkohlenwasserstoffreie aerosolformulierungen
EP1277467B1 (de) * 1991-06-10 2006-09-20 Schering Corporation Fluorchlorkohlenwasserstofffreie Aerosolformulierungen
CA2455115C (en) * 1991-12-12 2008-05-27 Glaxo Group Limited Pharmaceutical aerosol formulation
NZ246421A (en) * 1991-12-18 1996-05-28 Minnesota Mining & Mfg Aerosol formulation containing a drug and a propellant and which is substantially free of surfactant
MX9304585A (es) * 1992-07-31 1994-03-31 Glaxo Group Ltd Formulacion farmaceutica en aerosol, lata adecuada para liberar la formulacion e inhalador de dosis dosificada que comprende la lata.
ES2138074T3 (es) * 1993-03-29 2000-01-01 Lynchris Pharm Ltd Aerosol anestesico en base a lidocaina.
DE4323636A1 (de) * 1993-07-15 1995-01-19 Hoechst Ag Arzneistoffzubereitungen aus umhüllten, schwerstwasserlöslichen Arzneistoffen für Inhalationsarzneiformen und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
PT755247E (pt) 2004-06-30
EP0755247A1 (de) 1997-01-29
DK0755247T3 (da) 2004-05-17
WO1995027476A1 (en) 1995-10-19
EP0755247B1 (de) 2004-01-14
JPH10502906A (ja) 1998-03-17
US5508023A (en) 1996-04-16
CA2187447A1 (en) 1995-10-19
DE69532443T2 (de) 2004-12-02
ATE257695T1 (de) 2004-01-15
CA2187447C (en) 2005-06-14
ES2217277T3 (es) 2004-11-01
EP0755247A4 (de) 1999-05-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee