DE69531069D1 - Verfahren zur spezifischen immunabsorption von selektierten pathogenen faktoren zur behandlung von aids - Google Patents
Verfahren zur spezifischen immunabsorption von selektierten pathogenen faktoren zur behandlung von aidsInfo
- Publication number
- DE69531069D1 DE69531069D1 DE69531069T DE69531069T DE69531069D1 DE 69531069 D1 DE69531069 D1 DE 69531069D1 DE 69531069 T DE69531069 T DE 69531069T DE 69531069 T DE69531069 T DE 69531069T DE 69531069 D1 DE69531069 D1 DE 69531069D1
- Authority
- DE
- Germany
- Prior art keywords
- antibodies
- protein
- pathogenic factors
- specific
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000001717 pathogenic effect Effects 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 208000030507 AIDS Diseases 0.000 title 1
- 238000010521 absorption reaction Methods 0.000 title 1
- 239000008280 blood Substances 0.000 abstract 3
- 210000004369 blood Anatomy 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 2
- 101800001690 Transmembrane protein gp41 Proteins 0.000 abstract 2
- 229940047122 interleukins Drugs 0.000 abstract 2
- 108010076805 snowdrop lectin Proteins 0.000 abstract 2
- GOZMBJCYMQQACI-UHFFFAOYSA-N 6,7-dimethyl-3-[[methyl-[2-[methyl-[[1-[3-(trifluoromethyl)phenyl]indol-3-yl]methyl]amino]ethyl]amino]methyl]chromen-4-one;dihydrochloride Chemical compound Cl.Cl.C=1OC2=CC(C)=C(C)C=C2C(=O)C=1CN(C)CCN(C)CC(C1=CC=CC=C11)=CN1C1=CC=CC(C(F)(F)F)=C1 GOZMBJCYMQQACI-UHFFFAOYSA-N 0.000 abstract 1
- 208000029483 Acquired immunodeficiency Diseases 0.000 abstract 1
- 108091006027 G proteins Proteins 0.000 abstract 1
- 102000030782 GTP binding Human genes 0.000 abstract 1
- 108091000058 GTP-Binding Proteins 0.000 abstract 1
- 102000003814 Interleukin-10 Human genes 0.000 abstract 1
- 108090000174 Interleukin-10 Proteins 0.000 abstract 1
- 102000015696 Interleukins Human genes 0.000 abstract 1
- 108010063738 Interleukins Proteins 0.000 abstract 1
- 108090001090 Lectins Proteins 0.000 abstract 1
- 102000004856 Lectins Human genes 0.000 abstract 1
- 108010033276 Peptide Fragments Proteins 0.000 abstract 1
- 102000007079 Peptide Fragments Human genes 0.000 abstract 1
- 241000191967 Staphylococcus aureus Species 0.000 abstract 1
- 241000194017 Streptococcus Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000002596 correlated effect Effects 0.000 abstract 1
- 239000002523 lectin Substances 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Anesthesiology (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- External Artificial Organs (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITVR940096A IT1271593B (it) | 1994-11-30 | 1994-11-30 | Procedimento ed apparecchiatura per l'immunoadsorbimento specifico di virus hiv, di antigene gp120 e complesso cd4-gp120. |
| ITVR940096 | 1994-11-30 | ||
| PCT/IT1995/000206 WO1996016666A1 (en) | 1994-11-30 | 1995-11-30 | Method for the specific immunoadsorption of selected pathogenic factors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69531069D1 true DE69531069D1 (de) | 2003-07-17 |
| DE69531069T2 DE69531069T2 (de) | 2004-05-06 |
Family
ID=11427924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69531069T Expired - Fee Related DE69531069T2 (de) | 1994-11-30 | 1995-11-30 | Verfahren zur spezifischen immunabsorption von selektierten pathogenen faktoren zur behandlung von aids |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0954325B1 (de) |
| JP (1) | JP2000516193A (de) |
| AT (1) | ATE242637T1 (de) |
| AU (1) | AU4186496A (de) |
| DE (1) | DE69531069T2 (de) |
| ES (1) | ES2201125T3 (de) |
| IT (1) | IT1271593B (de) |
| WO (1) | WO1996016666A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998002174A1 (de) * | 1996-07-12 | 1998-01-22 | Imtec Immundiagnostika Gmbh | Selektives adsorbens zur bindung von retroviren |
| US6379708B1 (en) * | 1999-11-20 | 2002-04-30 | Cytologic, Llc | Method for enhancing immune responses in mammals |
| WO2006034507A2 (en) | 2004-09-24 | 2006-03-30 | Beth Israel - Deaconess Medical Center | Methods of diagnosing and treating complications of pregnancy |
| US20060153835A1 (en) * | 2005-01-12 | 2006-07-13 | Smith Henry J | Treatment of pre-eclampsia in pregnant women using targeted apheresis |
| US20090286271A1 (en) * | 2006-05-31 | 2009-11-19 | Karumanchi Ananth S | Methods of Diagnosing and Treating Complications of Pregnancy |
| US9241977B2 (en) | 2013-03-01 | 2016-01-26 | Arthrex, Inc. | Enhanced anabolic cytokine production and delivery system |
| ES2713388T3 (es) * | 2013-12-27 | 2019-05-21 | Eliaz Therapeutics Inc | Dispositivo de plasmaféresis |
| DE102016106510A1 (de) * | 2016-04-08 | 2017-10-12 | ToposNomos Ltd. | Verfahren und Vorrichtung zum extrakorporalen Entfernen von pathogenen und/oder überzähligen Bestandteilen aus einer Zellprobe eines Patienten |
| CN106267416B (zh) * | 2016-07-01 | 2019-02-19 | 翁炳焕 | 艾滋病治疗仪 |
| CN106267414B (zh) * | 2016-07-01 | 2019-02-19 | 翁炳焕 | 艾滋病免疫净化器 |
| FR3109734B1 (fr) | 2020-05-04 | 2025-04-11 | Univ Claude Bernard Lyon | Système de dialyse pour le traitement du sepsis |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1536425A (en) * | 1976-01-30 | 1978-12-20 | Nat Res Dev | Blood treatment |
| WO1980002805A1 (en) * | 1979-06-11 | 1980-12-24 | Gambro Ab | Process for the treating of and/or removal of substances from a liquid,especially whole blood,and a device and a membrane for the realization of said process |
| JPS57103649A (en) * | 1980-12-18 | 1982-06-28 | Asahi Chemical Ind | Sterilized gamma-globulin fixing column |
| EP0103184B1 (de) * | 1982-08-12 | 1990-01-17 | Kanegafuchi Chemical Industry Co., Ltd. | Aktivierung bioverträglicher Terpolymere mit biologischen Stoffen, deren anzubindende Komplemente pathologische Effektoren sind |
| US5037649A (en) * | 1985-01-11 | 1991-08-06 | Imre Corporation | Method for treatment of HIV-infected patients |
| JPH0720880B2 (ja) * | 1987-06-10 | 1995-03-08 | ジ イミューン リスポンス コーポレーション,インコーポレーテッド | レトロウイルス疾患の予防および治療 |
| US4831118A (en) * | 1987-08-07 | 1989-05-16 | Scripps Clinic And Research Foundation | Flouroplastic immunoaffinity columns for purification of blood proteins |
| CA2203443C (en) * | 1990-11-08 | 2001-08-28 | Robert O. Ralston | Hepatitis c virus asialoglycoproteins |
| US5223397A (en) * | 1991-06-05 | 1993-06-29 | Sangstat Medical Corporation | Soluble hla cross-match |
| DE4331358A1 (de) * | 1992-10-12 | 1994-04-14 | Braun Melsungen Ag | Verfahren zur quantitativen selektiven Entfernung oder präparativen Gewinnung von Tumor-Nekrose-Faktor (TNF) oder/und Lipopolysacchariden (LPS) aus wäßrigen Flüssigkeiten |
| WO1994027698A2 (en) * | 1993-05-28 | 1994-12-08 | Baxter International Inc. | Continuous centrifugation process for the separation of biologic components from heterogeneous cell populations |
-
1994
- 1994-11-30 IT ITVR940096A patent/IT1271593B/it active IP Right Grant
-
1995
- 1995-11-30 DE DE69531069T patent/DE69531069T2/de not_active Expired - Fee Related
- 1995-11-30 AT AT95940399T patent/ATE242637T1/de not_active IP Right Cessation
- 1995-11-30 EP EP95940399A patent/EP0954325B1/de not_active Expired - Lifetime
- 1995-11-30 JP JP08518558A patent/JP2000516193A/ja not_active Ceased
- 1995-11-30 AU AU41864/96A patent/AU4186496A/en not_active Abandoned
- 1995-11-30 WO PCT/IT1995/000206 patent/WO1996016666A1/en not_active Ceased
- 1995-11-30 ES ES95940399T patent/ES2201125T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2201125T3 (es) | 2004-03-16 |
| ITVR940096A1 (it) | 1996-05-30 |
| JP2000516193A (ja) | 2000-12-05 |
| AU4186496A (en) | 1996-06-19 |
| IT1271593B (it) | 1997-06-04 |
| DE69531069T2 (de) | 2004-05-06 |
| EP0954325A1 (de) | 1999-11-10 |
| EP0954325B1 (de) | 2003-06-11 |
| ITVR940096A0 (it) | 1994-11-30 |
| WO1996016666A1 (en) | 1996-06-06 |
| ATE242637T1 (de) | 2003-06-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0308936B1 (de) | Antikörper-Heterokonjugate zur Töting von HIV-infizierten Zellen | |
| Robinson Jr et al. | Antibodies to the primary immunodominant domain of human immunodeficiency virus type 1 (HIV-1) glycoprotein gp41 enhance HIV-1 infection in vitro | |
| ATE242637T1 (de) | Verfahren zur spezifischen immunabsorption von selektierten pathogenen faktoren zur behandlung von aids | |
| Buchacher et al. | Generation of human monoclonal antibodies against HIV-1 proteins; electrofusion and Epstein-Barr virus transformation for peripheral blood lymphocyte immortalization | |
| Berggård | On a γ-globulin of low molecular weight in normal human plasma and urine | |
| Gilljam | Envelope glycoproteins of HIV-1, HIV-2, and SIV purified with Galanthus nivalis agglutinin induce strong immune responses | |
| DE69126301D1 (de) | Hiv-induzierte synzytien blockierender anti-cd-4-antikörper | |
| Pincus et al. | In vitro efficacy of anti-HIV immunotoxins targeted by various antibodies to the envelope protein | |
| US5286852A (en) | Antibodies specific towards HIV-1 gp 48 | |
| YU22693A (sh) | Rekombinantna humana monoklonalna antitela koja neutrališu hiv, za sprečavanje i tretiranje hiv infekcije | |
| Hutt-Fletcher et al. | Studies of the Epstein Barr virus receptor found on Raji cells. II. A comparison of lymphocyte binding sites for Epstein Barr virus and C3d. | |
| Pak-Leong | Isolation of specific IgM monoclonal antibodies by affinity chromatography using alkaline buffers | |
| Matsushita et al. | Selective killing of HIV-infected cells by anti-gp120 immunotoxins | |
| Chams et al. | Biological properties of anti-CD4 autoantibodies purified from HIV-infected patients | |
| MX2025005079A (es) | Proteinas de union a antigeno | |
| Chen et al. | HIV-1 gp41 enhances major histocompatibility complex class I and ICAM-1 expression on H9 and U937 cells | |
| Van Joost | An attempt to identify the nature of immunoglobulin‐complement deposits in the skin in lupus erythematosus | |
| Chen et al. | A common immunological epitope existing between HIV-1 gp41 and human interferon-α and-β | |
| DE60216422T2 (de) | Natürlicher antikörper mit wirkung gegen das hiv virus | |
| Hinkula et al. | Enzyme immunoassay (ELISA) for the evaluation of antibodies directed to the CD4 receptor-binding site of the HIV gp120 molecule | |
| CA2028121A1 (en) | Human monoclonal antibodies to human immunodeficiency virus | |
| EP0374053B1 (de) | Arzneimittel für die Behandlung oder die Verhütung von Infektionen mit HIV durch Immunisierung, und Verfahren zur Herstellung | |
| Ushijima et al. | Removal of HIV antigens and HIV-infected cells in vitro using immunomagnetic beads | |
| JPH01135725A (ja) | 抗−pH不安定アルフアインターフエロン抗体の製造方法 | |
| AU2002257620A1 (en) | Natural antibodie active against HIV virus |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |