DE69525738D1 - Heterocyclische verbindungen und ihre herstellung und verwendung - Google Patents

Heterocyclische verbindungen und ihre herstellung und verwendung

Info

Publication number
DE69525738D1
DE69525738D1 DE69525738T DE69525738T DE69525738D1 DE 69525738 D1 DE69525738 D1 DE 69525738D1 DE 69525738 T DE69525738 T DE 69525738T DE 69525738 T DE69525738 T DE 69525738T DE 69525738 D1 DE69525738 D1 DE 69525738D1
Authority
DE
Germany
Prior art keywords
independently
image
alkoxy
optionally substituted
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69525738T
Other languages
English (en)
Inventor
Lone Jeppesen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Application granted granted Critical
Publication of DE69525738D1 publication Critical patent/DE69525738D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69525738T 1994-02-11 1995-01-30 Heterocyclische verbindungen und ihre herstellung und verwendung Expired - Fee Related DE69525738D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK18394 1994-02-11
DK135194 1994-11-25
PCT/DK1995/000044 WO1995021842A1 (en) 1994-02-11 1995-01-30 Heterocyclic compounds and their preparation and use

Publications (1)

Publication Number Publication Date
DE69525738D1 true DE69525738D1 (de) 2002-04-11

Family

ID=26063483

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69525738T Expired - Fee Related DE69525738D1 (de) 1994-02-11 1995-01-30 Heterocyclische verbindungen und ihre herstellung und verwendung

Country Status (15)

Country Link
US (1) US5741785A (de)
EP (1) EP0743945B1 (de)
JP (1) JPH09508632A (de)
KR (1) KR970701192A (de)
CN (1) CN1045964C (de)
AT (1) ATE214069T1 (de)
AU (1) AU692524B2 (de)
CA (1) CA2182957A1 (de)
DE (1) DE69525738D1 (de)
FI (1) FI963130A (de)
HU (1) HUT76323A (de)
IL (1) IL112588A (de)
NO (1) NO306781B1 (de)
NZ (1) NZ281183A (de)
WO (1) WO1995021842A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL319406A1 (en) * 1994-09-30 1997-08-04 Basf Ag Novel heterocyclically substituted imidazoqunoxalinones, their production and application
FR2743363A1 (fr) * 1996-01-10 1997-07-11 Rhone Poulenc Rorer Sa 5h,10h-imidazo(1,2-a)indeno(1,2-e)pyrazine-a-ones substituees en position 2, leur preparation et les medicaments les contenant
DE19611476A1 (de) * 1996-03-22 1997-09-25 Basf Ag Neue heterocyclische substituierte Imidazolo-chinoxalinone, ihre Herstellung und Verwendung
IL125950A0 (en) * 1997-09-05 1999-04-11 Pfizer Prod Inc Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
ES2536906T3 (es) 2006-12-13 2015-05-29 Aska Pharmaceutical Co., Ltd. Derivado de quinoxalina
CA2672860C (en) * 2006-12-28 2013-01-29 Abbott Laboratories Inhibitors of poly(adp-ribose)polymerase
WO2023042887A1 (ja) 2021-09-15 2023-03-23 国立大学法人 琉球大学 認知機能低下、または過体重もしくは肥満症を処置することに用いるための医薬組成物
WO2023042888A1 (ja) 2021-09-15 2023-03-23 国立大学法人 琉球大学 認知機能低下、または過体重もしくは肥満症を処置することに用いるための医薬組成物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2043637B (en) * 1979-02-09 1983-03-16 Roussel Lab Ltd Heterotricyclic derivatives
FR2448541A1 (fr) * 1979-02-09 1980-09-05 Roussel Uclaf Nouveaux derives de l'oxoimidazoquinoxaline et leurs sels, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
GB2043064B (en) * 1979-02-09 1983-04-13 Roussel Lab Ltd Oximidazoquinoxaline derivatives
US5055465A (en) * 1989-05-31 1991-10-08 Berlex Laboratories, Inc. Imidazoquinoxalinones, their aza analogs and process for their preparation
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
US5182386A (en) * 1991-08-27 1993-01-26 Neurogen Corporation Certain imidazoquinoxalinones; a new class of gaba brain receptor ligands
AU3767793A (en) * 1992-04-03 1993-11-08 Yamanouchi Pharmaceutical Co., Ltd. Fused quinoxalinone derivative and pharmaceutical composition containing the same
DE4310523A1 (de) * 1993-03-31 1994-10-06 Basf Ag Imidazolo-chinoxalinone zur Behandlung zentralnervöser Erkrankungen
DE4329970A1 (de) * 1993-03-31 1994-10-06 Basf Ag Neue Imidazolo-chinoxalinone, ihre Hestellung und Verwendung
CN1041928C (zh) * 1993-03-31 1999-02-03 Basf公司 新的咪唑并喹喔啉酮及其制备方法和用途

Also Published As

Publication number Publication date
ATE214069T1 (de) 2002-03-15
AU692524B2 (en) 1998-06-11
NZ281183A (en) 1998-05-27
JPH09508632A (ja) 1997-09-02
EP0743945B1 (de) 2002-03-06
CN1045964C (zh) 1999-10-27
IL112588A (en) 1999-07-14
US5741785A (en) 1998-04-21
NO963337D0 (no) 1996-08-09
CA2182957A1 (en) 1995-08-17
NO306781B1 (no) 1999-12-20
IL112588A0 (en) 1995-05-26
KR970701192A (ko) 1997-03-17
HUT76323A (en) 1997-08-28
WO1995021842A1 (en) 1995-08-17
EP0743945A1 (de) 1996-11-27
FI963130A0 (fi) 1996-08-09
FI963130A (fi) 1996-10-09
NO963337L (no) 1996-10-11
CN1145071A (zh) 1997-03-12
AU1805595A (en) 1995-08-29
HU9602203D0 (en) 1996-10-28

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DE69525738D1 (de) Heterocyclische verbindungen und ihre herstellung und verwendung
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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee