DE69525366D1 - Die verwendung von bmp-protein-rezeptor komplexen für das screening von substanzen aus dem knochenmetabolismus und zellen die mit einem typ i- und typ ii-bmp-rezeptor co-transfiziertsind - Google Patents
Die verwendung von bmp-protein-rezeptor komplexen für das screening von substanzen aus dem knochenmetabolismus und zellen die mit einem typ i- und typ ii-bmp-rezeptor co-transfiziertsindInfo
- Publication number
- DE69525366D1 DE69525366D1 DE69525366T DE69525366T DE69525366D1 DE 69525366 D1 DE69525366 D1 DE 69525366D1 DE 69525366 T DE69525366 T DE 69525366T DE 69525366 T DE69525366 T DE 69525366T DE 69525366 D1 DE69525366 D1 DE 69525366D1
- Authority
- DE
- Germany
- Prior art keywords
- bmp
- kinase protein
- receptor kinase
- type
- bmp receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33417894A | 1994-11-04 | 1994-11-04 | |
US08/462,467 US6210899B1 (en) | 1994-11-04 | 1995-06-05 | Use of a BMP protein receptor complex for screening bone metabolism actives and cells co-transfected with a type II BMP receptor and type I BMP receptor |
PCT/US1995/014027 WO1996014579A1 (en) | 1994-11-04 | 1995-10-30 | The use of a bmp protein receptor complex for screening bone metabolism actives and cells co-transfected with a type ii bmp receptor and a type i bmp receptor |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69525366D1 true DE69525366D1 (de) | 2002-03-21 |
DE69525366T2 DE69525366T2 (de) | 2002-11-07 |
Family
ID=26989071
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69525366T Expired - Fee Related DE69525366T2 (de) | 1994-11-04 | 1995-10-30 | Die verwendung von bmp-protein-rezeptor komplexen für das screening von substanzen aus dem knochenmetabolismus und zellen die mit einem typ i- und typ ii-bmp-rezeptor co-transfiziertsind |
Country Status (8)
Country | Link |
---|---|
US (2) | US6210899B1 (de) |
EP (1) | EP0789844B1 (de) |
JP (1) | JP3527248B2 (de) |
AT (1) | ATE213064T1 (de) |
AU (1) | AU710559B2 (de) |
DE (1) | DE69525366T2 (de) |
DK (1) | DK0789844T3 (de) |
WO (1) | WO1996014579A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6306622B1 (en) * | 1994-11-04 | 2001-10-23 | The Procter & Gamble Co. | cDNA encoding a BMP type II receptor |
WO1996018735A2 (en) * | 1994-12-14 | 1996-06-20 | Amgen Boulder Inc. | Tgf-beta superfamily type ii receptor having binding affinity for bone morphogenic protein (bmp) |
JP2000514777A (ja) * | 1995-08-14 | 2000-11-07 | クリエイティブ バイオモレキュールズ,インコーポレイテッド | 骨形成タンパク質(op−1)およびそのアナログの細胞表面レセプターalk−1およびそのアナログへの結合 |
IL132922A0 (en) * | 1997-05-16 | 2001-03-19 | Procter & Gamble | The use of a bone morphogenetic protein (bmp) receptor complex for screening |
AU2003230904A1 (en) * | 2002-04-12 | 2003-10-27 | Trustees Of Boston University | Methods for lightening skin and hair |
EP2789342A1 (de) | 2004-06-17 | 2014-10-15 | Thrasos Innovation, Inc. | Verbindungen im Zusammenhang mit TDF und Analoga davon |
ES2537527T3 (es) | 2005-09-20 | 2015-06-09 | Thrasos Innovation, Inc. | Compuestos relacionados con el TDF y análogos de los mismos |
US20070293587A1 (en) * | 2006-05-23 | 2007-12-20 | Haley Jeffrey T | Combating sinus, throat, and blood infections with xylitol delivered in the mouth |
WO2010051032A1 (en) * | 2008-10-31 | 2010-05-06 | Synthes Usa, Llc | Method and device for activating stem cells |
KR101451340B1 (ko) * | 2012-08-02 | 2014-10-15 | (주)애드바이오텍 | 모발 생장 촉진용 조성물 |
KR20240001181A (ko) * | 2021-04-28 | 2024-01-03 | 더 트러스티스 오브 컬럼비아 유니버시티 인 더 시티 오브 뉴욕 | Covid-19 및 신종 변이의 치료 및 예방을 위한 항체 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5013649A (en) | 1986-07-01 | 1991-05-07 | Genetics Institute, Inc. | DNA sequences encoding osteoinductive products |
ZA874681B (en) | 1986-07-01 | 1988-04-27 | Genetics Inst | Novel osteoinductive factors |
CA2002011A1 (en) | 1988-11-14 | 1990-05-14 | Anthony F. Purchio | Normal human growth regulatory receptor for tgf-beta |
US5168050A (en) | 1990-05-24 | 1992-12-01 | Genentech, Inc. | Mammalian expression of the bone morphogenetic protein-2b using bmp2a/bmp2b fusion |
AU654724B2 (en) | 1991-05-10 | 1994-11-17 | Salk Institute For Biological Studies, The | Cloning and recombinant production of receptor(s) of the activin/TGF-beta superfamily |
US5216126A (en) | 1991-06-19 | 1993-06-01 | Genentech, Inc. | Receptor polypeptides and their production and uses |
JP4124815B2 (ja) | 1991-10-31 | 2008-07-23 | ホワイトヘッド インスティチュート フォー バイオメディカル リサーチ | TGF−β型受容体cDNAおよびその用途 |
WO1993019177A1 (en) | 1992-03-18 | 1993-09-30 | The General Hospital Corporation | FOUR NOVEL RECEPTORS OF THE TGF-β RECEPTOR FAMILY |
ATE234920T1 (de) | 1992-11-17 | 2003-04-15 | Ludwig Inst Cancer Res | Aktivin-rezeptor-ähnliche kinasen, proteine mit serin/threonin kinase domänen und deren anwendungen |
US6291206B1 (en) | 1993-09-17 | 2001-09-18 | Genetics Institute, Inc. | BMP receptor proteins |
US6248554B1 (en) | 1993-11-24 | 2001-06-19 | The Procter & Gamble Company | DNA sequence coding for a BMP receptor |
-
1995
- 1995-06-05 US US08/462,467 patent/US6210899B1/en not_active Expired - Fee Related
- 1995-10-30 EP EP95937676A patent/EP0789844B1/de not_active Expired - Lifetime
- 1995-10-30 JP JP51537396A patent/JP3527248B2/ja not_active Expired - Fee Related
- 1995-10-30 AT AT95937676T patent/ATE213064T1/de not_active IP Right Cessation
- 1995-10-30 DK DK95937676T patent/DK0789844T3/da active
- 1995-10-30 DE DE69525366T patent/DE69525366T2/de not_active Expired - Fee Related
- 1995-10-30 AU AU39713/95A patent/AU710559B2/en not_active Ceased
- 1995-10-30 WO PCT/US1995/014027 patent/WO1996014579A1/en active IP Right Grant
-
2000
- 2000-12-20 US US09/742,153 patent/US7105290B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1996014579A1 (en) | 1996-05-17 |
AU3971395A (en) | 1996-05-31 |
ATE213064T1 (de) | 2002-02-15 |
EP0789844B1 (de) | 2002-02-06 |
US7105290B2 (en) | 2006-09-12 |
DK0789844T3 (da) | 2002-05-27 |
US6210899B1 (en) | 2001-04-03 |
EP0789844A1 (de) | 1997-08-20 |
JPH10510047A (ja) | 1998-09-29 |
DE69525366T2 (de) | 2002-11-07 |
US20030096296A1 (en) | 2003-05-22 |
JP3527248B2 (ja) | 2004-05-17 |
AU710559B2 (en) | 1999-09-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |