DE69523733T2 - Thermisch gelierende trägerstoffe zur arzneistoffabgabe, die zelluloseether enthalten - Google Patents

Thermisch gelierende trägerstoffe zur arzneistoffabgabe, die zelluloseether enthalten

Info

Publication number
DE69523733T2
DE69523733T2 DE69523733T DE69523733T DE69523733T2 DE 69523733 T2 DE69523733 T2 DE 69523733T2 DE 69523733 T DE69523733 T DE 69523733T DE 69523733 T DE69523733 T DE 69523733T DE 69523733 T2 DE69523733 T2 DE 69523733T2
Authority
DE
Germany
Prior art keywords
cellulose ethers
geling
disposal
thermally
substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69523733T
Other languages
English (en)
Other versions
DE69523733D1 (de
Inventor
Bhagwati P Kabra
John C Lang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Publication of DE69523733D1 publication Critical patent/DE69523733D1/de
Application granted granted Critical
Publication of DE69523733T2 publication Critical patent/DE69523733T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69523733T 1994-08-30 1995-08-23 Thermisch gelierende trägerstoffe zur arzneistoffabgabe, die zelluloseether enthalten Expired - Lifetime DE69523733T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29824494A 1994-08-30 1994-08-30
PCT/US1995/010877 WO1996006597A1 (en) 1994-08-30 1995-08-23 Thermally-gelling ophthalmic drug delivery vehicles containing cellulose ethers

Publications (2)

Publication Number Publication Date
DE69523733D1 DE69523733D1 (de) 2001-12-13
DE69523733T2 true DE69523733T2 (de) 2002-08-01

Family

ID=23149679

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69523733T Expired - Lifetime DE69523733T2 (de) 1994-08-30 1995-08-23 Thermisch gelierende trägerstoffe zur arzneistoffabgabe, die zelluloseether enthalten

Country Status (15)

Country Link
US (1) US5618800A (de)
EP (1) EP0725628B1 (de)
JP (1) JPH09508143A (de)
CN (1) CN1162148C (de)
AT (1) ATE208186T1 (de)
AU (1) AU686455B2 (de)
CA (1) CA2172373C (de)
DE (1) DE69523733T2 (de)
DK (1) DK0725628T3 (de)
ES (1) ES2162638T3 (de)
HK (1) HK1012558A1 (de)
MX (1) MX9601591A (de)
PT (1) PT725628E (de)
TW (1) TW460288B (de)
WO (1) WO1996006597A1 (de)

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US6174524B1 (en) 1999-03-26 2001-01-16 Alcon Laboratories, Inc. Gelling ophthalmic compositions containing xanthan gum
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US20040258763A1 (en) * 1999-02-03 2004-12-23 Bell Steve J.D. Methods of manufacture and use of calcium phosphate particles containing allergens
CA2361421A1 (en) * 1999-02-03 2000-08-10 Biosante Pharmaceuticals, Inc. Therapeutic calcium phosphate particles and methods of manufacture and use
US20020054914A1 (en) * 1999-02-03 2002-05-09 Tulin Morcol Compositions and methods for therapuetic agents complexed with calcium phosphate and encased by casein
WO2000059947A1 (en) * 1999-04-01 2000-10-12 The Dow Chemical Company Enhanced gel strength methylcellulose
US6235893B1 (en) 1999-04-01 2001-05-22 The Dow Chemical Company Process for making cellulose ether having enhanced gel strength
US6932759B2 (en) 1999-06-09 2005-08-23 Gene W. Kammerer Surgical instrument and method for treating female urinary incontinence
US7121997B2 (en) 1999-06-09 2006-10-17 Ethicon, Inc. Surgical instrument and method for treating female urinary incontinence
EP1581162B1 (de) 1999-06-09 2011-04-20 Ethicon, Inc. Vorrichtung zum justieren von polymerimplantaten an weichen oberflächen
US7226407B2 (en) 1999-06-09 2007-06-05 Ethicon, Inc. Surgical instrument and method for treating female urinary incontinence
ES2199873T3 (es) 1999-11-01 2004-03-01 Alcon Inc. Composiciones farmaceuticas que contienen un farmaco antibiotico de fluoroquinolona y goma xantan.
US7097855B1 (en) 2000-01-31 2006-08-29 Massachusetts Institute Of Technology Transdermal thermal polymerization
US7131943B2 (en) 2000-03-09 2006-11-07 Ethicon, Inc. Surgical instrument and method for treating organ prolapse conditions
PL199321B1 (pl) 2000-07-28 2008-09-30 Alcon Inc Kompozycje farmaceutyczne zawierające tobramycynę i gumę ksantanową
US20030060447A1 (en) * 2002-04-24 2003-03-27 Mutlu Karakelle Non-aspirating transitional viscoelastics for use in surgery
WO2002040056A2 (en) 2000-11-06 2002-05-23 Alcon, Inc Carrageenan viscoelastics for ocular surgery
US20030185892A1 (en) * 2001-08-17 2003-10-02 Bell Steve J. D. Intraocular delivery compositions and methods
DE10224352A1 (de) * 2002-06-01 2003-12-11 Mueller Schulte Detlef Thermosensitive Polymerträger mit veränderbarer physikalischer Struktur für die biochemische Analytik, Diagnostik und Therapie
US7727549B2 (en) * 2002-07-15 2010-06-01 Alcon, Inc. Pharmaceutical compositions for otic use
DE10350248A1 (de) * 2003-10-28 2005-06-16 Magnamedics Gmbh Thermosensitive, biokompatible Polymerträger mit veränderbarer physikalischer Struktur für die Therapie, Diagnostik und Analytik
WO2006050368A2 (en) 2004-11-01 2006-05-11 Biosante Pharmaceuticals, Inc. Therapeutic calcium phosphate particles iin use for aesthetic or cosmetic medicine, and methods of manufacture and use
CA2617437A1 (en) 2005-08-04 2007-02-08 C.R. Bard, Inc. Pelvic implant systems and methods
ES2470338T3 (es) 2005-11-14 2014-06-23 C.R. Bard, Inc. Sistema de anclaje de eslinga
US20070140897A1 (en) * 2005-12-21 2007-06-21 Hongna Wang Ph stable biguanide composition and method of treatment and prevention of infections
US20070142478A1 (en) * 2005-12-21 2007-06-21 Erning Xia Combination antimicrobial composition and method of use
US20070141091A1 (en) * 2005-12-21 2007-06-21 Erning Xia Biguanide ointment and method of treatment and prevention of infections
WO2008033950A2 (en) 2006-09-13 2008-03-20 C. R. Bard, Inc. Urethral support system
DE102006062140A1 (de) * 2006-12-22 2008-06-26 Dow Wolff Cellulosics Gmbh Celluloseetheradditive für die Extrusion keramischer Massen
US20080161405A1 (en) * 2006-12-29 2008-07-03 Erning Xia Biguanide Composition and Method of Treatment and Prevention of Infections
US8206280B2 (en) 2007-11-13 2012-06-26 C. R. Bard, Inc. Adjustable tissue support member
DE102007059939A1 (de) 2007-12-12 2009-06-18 Müller-Schulte, Detlef, Dr. Auflösbare, magnetische und unmagnetische Polymerträger zur Abtrennung und Wiedergewinnung von Zellen und Biosubstanzen
US8449573B2 (en) 2008-12-05 2013-05-28 Boston Scientific Scimed, Inc. Insertion device and method for delivery of a mesh carrier
US8968334B2 (en) 2009-04-17 2015-03-03 Boston Scientific Scimed, Inc. Apparatus for delivering and anchoring implantable medical devices
US9301750B2 (en) 2009-11-03 2016-04-05 Boston Scientific Scimed, Inc. Device and method for delivery of mesh-based devices
GB201105408D0 (en) * 2011-03-30 2011-05-11 Glaxo Group Ltd Composition
KR101740300B1 (ko) * 2013-07-17 2017-05-26 다우 글로벌 테크놀로지스 엘엘씨 히드록시알킬 메틸셀룰로스를 포함하는 점막으로의 적용을 위한 조성물
US20160228559A1 (en) * 2013-09-25 2016-08-11 Dow Global Technologies Llc Composition for application to a mucosa comprising a cellulose ether
JP2018509473A (ja) * 2015-03-24 2018-04-05 ダウ グローバル テクノロジーズ エルエルシー ポリマーの水溶液
AU2016304585B2 (en) 2015-08-05 2023-04-06 Children's Medical Center Corporation Compositions with permeation enhancers for drug delivery
EP3512501A4 (de) * 2016-09-14 2020-04-29 Children's Medical Center Corporation Zusammensetzungen mit permeationsförderern zur wirkstofffreisetzung

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US3856919A (en) * 1970-06-08 1974-12-24 Burton Parsons Chemicals Inc Ophthalmic solution
US3767788A (en) * 1970-06-08 1973-10-23 Burton Parsons Chemicals Inc Ophthalmic solution
SE403782B (sv) * 1973-03-14 1978-09-04 Mo Och Domsjoe Ab Nonjoniska cellulosaetrar
US4001211A (en) * 1974-12-02 1977-01-04 The Dow Chemical Company Pharmaceutical capsules from improved thermogelling methyl cellulose ethers
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US4136177A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Xanthan gum therapeutic compositions
US4136173A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
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US4474751A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
US4474752A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
FR2588189B1 (fr) * 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
DE3700681A1 (de) * 1987-01-12 1988-07-21 Breveteam Sa Sphaerisches faseraggregat, insbesondere als fuell- oder polstermaterial
US5279660A (en) * 1988-05-24 1994-01-18 Berol Nobel Stenungsund Ab Use of viscosity-adjusting agent to counteract viscosity decrease upon temperature increase of a water-based system
SE461396B (sv) * 1988-05-24 1990-02-12 Berol Kemi Ab Saett att vid temperaturhoejning motverka viskositetsnedgaang alternativt aastadkomma viskositetsoekning hos ett vattenbaserat system innehaallande en polymer som viskositetsgivare
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US5077033A (en) * 1990-08-07 1991-12-31 Mediventures Inc. Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide
US5124151A (en) * 1990-08-07 1992-06-23 Mediventures Inc. Drug delivery by injection with thermo-irreversible gels
SE9003712L (sv) * 1990-11-22 1992-01-07 Kabi Pharmacia Ab Gelbildande flytande baerarkomposition samt anvaendning daerav i farmaceutiska kompositioner
US5212162A (en) * 1991-03-27 1993-05-18 Alcon Laboratories, Inc. Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions
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US5470881A (en) * 1993-09-09 1995-11-28 West Virginia University Research Corporation Urea ophthalmic ointment and solution

Also Published As

Publication number Publication date
JPH09508143A (ja) 1997-08-19
ES2162638T3 (es) 2002-01-01
US5618800A (en) 1997-04-08
MX9601591A (es) 1997-05-31
WO1996006597A1 (en) 1996-03-07
CN1162148C (zh) 2004-08-18
AU3496595A (en) 1996-03-22
EP0725628A1 (de) 1996-08-14
HK1012558A1 (en) 1999-08-06
CN1134662A (zh) 1996-10-30
DK0725628T3 (da) 2001-12-27
TW460288B (en) 2001-10-21
EP0725628B1 (de) 2001-11-07
DE69523733D1 (de) 2001-12-13
AU686455B2 (en) 1998-02-05
ATE208186T1 (de) 2001-11-15
CA2172373C (en) 1999-03-16
PT725628E (pt) 2002-03-28
CA2172373A1 (en) 1996-03-07

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Legal Events

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