DE69521315T2 - Hirudin enthaltende pharmazeutische zusammensetzungen - Google Patents

Hirudin enthaltende pharmazeutische zusammensetzungen

Info

Publication number
DE69521315T2
DE69521315T2 DE69521315T DE69521315T DE69521315T2 DE 69521315 T2 DE69521315 T2 DE 69521315T2 DE 69521315 T DE69521315 T DE 69521315T DE 69521315 T DE69521315 T DE 69521315T DE 69521315 T2 DE69521315 T2 DE 69521315T2
Authority
DE
Germany
Prior art keywords
hirudine
pharmaceutical compositions
containing pharmaceutical
hirudin
sugar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69521315T
Other languages
English (en)
Other versions
DE69521315D1 (de
Inventor
Tudor Arvinte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCP GEN-PHARMA AG ZUERICH CH
Original Assignee
UCP Gen Pharma AG
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCP Gen Pharma AG, Novartis AG filed Critical UCP Gen Pharma AG
Application granted granted Critical
Publication of DE69521315D1 publication Critical patent/DE69521315D1/de
Publication of DE69521315T2 publication Critical patent/DE69521315T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • A61K38/58Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69521315T 1994-01-26 1995-01-25 Hirudin enthaltende pharmazeutische zusammensetzungen Expired - Lifetime DE69521315T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9401447A GB9401447D0 (en) 1994-01-26 1994-01-26 Pharmaceutical compositions
PCT/IB1995/000053 WO1995020399A1 (en) 1994-01-26 1995-01-25 Pharmaceutical compositions comprising hirudin

Publications (2)

Publication Number Publication Date
DE69521315D1 DE69521315D1 (de) 2001-07-19
DE69521315T2 true DE69521315T2 (de) 2001-10-31

Family

ID=10749331

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69521315T Expired - Lifetime DE69521315T2 (de) 1994-01-26 1995-01-25 Hirudin enthaltende pharmazeutische zusammensetzungen

Country Status (20)

Country Link
US (1) US6436901B1 (de)
EP (1) EP0758905B1 (de)
JP (2) JP3260760B2 (de)
AT (1) ATE201996T1 (de)
AU (1) AU1391595A (de)
CA (1) CA2181907A1 (de)
DE (1) DE69521315T2 (de)
DK (1) DK0758905T3 (de)
ES (1) ES2159621T3 (de)
FI (1) FI962979A (de)
GB (1) GB9401447D0 (de)
GR (1) GR3036574T3 (de)
HU (1) HU214823B (de)
IL (1) IL112388A0 (de)
MX (1) MX9603010A (de)
NO (1) NO963113L (de)
NZ (1) NZ278433A (de)
PT (1) PT758905E (de)
WO (1) WO1995020399A1 (de)
ZA (1) ZA95577B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6267958B1 (en) 1995-07-27 2001-07-31 Genentech, Inc. Protein formulation
DE19607239A1 (de) 1996-02-27 1997-08-28 Behringwerke Ag Pharmazeutische Zusammensetzung, enthaltend Hirudin und Verfahren zu deren Herstellung
US6653062B1 (en) 2000-07-26 2003-11-25 Wisconsin Alumni Research Foundation Preservation and storage medium for biological materials
CA2433936A1 (en) * 2001-01-23 2002-08-22 Boston Scientific Corporation Localized myocardial injection method for treating ischemic myocardium
US7795205B2 (en) * 2004-04-12 2010-09-14 Canyon Pharmaceuticals, Inc. Methods for effecting regression of tumor mass and size in a metastasized pancreatic tumor
ATE368461T1 (de) 2004-10-29 2007-08-15 Pharma Mar Sa Zusammensetzungen enthaltend ecteinascidin und einen disaccharide

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3342139A1 (de) * 1983-11-22 1985-05-30 Ciba-Geigy Ag, Basel Desulfatohirudine, verfahren zu ihrer herstellung und pharmazeutische mittel
DE3586333T2 (de) 1984-03-27 1992-12-10 Transgene Sa Expressionsvektoren fuer hirudin, transformierte zellen und verfahren zur herstellung von hirudin.
DE3438296A1 (de) 1984-04-18 1985-11-07 Hoechst Ag, 6230 Frankfurt Neue polypeptide mit blutgerinnungshemmender wirkung, verfahren zu deren herstellung bzw. gewinnung, deren verwendung und diese enthaltende mittel
DE3445532A1 (de) 1984-12-13 1986-06-19 Plantorgan Werk Heinrich G.E. Christensen, KG, 2903 Bad Zwischenahn Hirudin-pa, desulfatohirudine-pa, verfahren zur herstellung und pharmazeutische mittel, die diese wirkstoffe enthalten
DE3804600A1 (de) 1988-02-13 1989-08-24 Basf Ag Mischung aus einer thrombolytisch wirkenden und einer antithrombotischen substanz
GB8817161D0 (en) * 1988-07-19 1988-08-24 Ciba Geigy Ag Modified proteins
IT1243358B (it) 1990-07-23 1994-06-10 Iketon Farmaceutici Srl Composizioni farmaceutiche per la somministrazione orale di irudina
AU659432B2 (en) 1991-03-08 1995-05-18 Novartis Ag A method for the inhibition or prevention of tumor cell metastasis with hirudin
GB9303275D0 (en) 1993-02-18 1993-04-07 Ciba Geigy Ag Pharmaceutical compositions
GB9401448D0 (en) 1994-01-26 1994-03-23 Ciba Geigy Ag Stable dry powders

Also Published As

Publication number Publication date
MX9603010A (es) 1998-01-31
IL112388A0 (en) 1995-03-30
DK0758905T3 (da) 2001-09-03
JPH09508377A (ja) 1997-08-26
NZ278433A (en) 1997-03-24
EP0758905A1 (de) 1997-02-26
JP3260760B2 (ja) 2002-02-25
HU214823B (hu) 1998-06-29
NO963113L (no) 1996-09-17
GR3036574T3 (en) 2001-12-31
ATE201996T1 (de) 2001-06-15
GB9401447D0 (en) 1994-03-23
NO963113D0 (no) 1996-07-25
HU9602037D0 (en) 1996-09-30
FI962979A0 (fi) 1996-07-26
ES2159621T3 (es) 2001-10-16
DE69521315D1 (de) 2001-07-19
EP0758905B1 (de) 2001-06-13
JP2001026548A (ja) 2001-01-30
WO1995020399A1 (en) 1995-08-03
PT758905E (pt) 2001-11-30
FI962979A (fi) 1996-07-26
CA2181907A1 (en) 1995-08-03
HUT74879A (en) 1997-02-28
ZA95577B (en) 1995-07-26
AU1391595A (en) 1995-08-15
US6436901B1 (en) 2002-08-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: UCP GEN-PHARMA AG, ZUERICH, CH

8328 Change in the person/name/address of the agent

Representative=s name: REITSTOETTER, KINZEBACH & PARTNER (GBR), 81679 MUENCHEN