DE69518192D1 - Verfahren zur Herstellung von N-Alkyl-N-Pyridinyl-1H-Indol-1-Aminen - Google Patents

Verfahren zur Herstellung von N-Alkyl-N-Pyridinyl-1H-Indol-1-Aminen

Info

Publication number
DE69518192D1
DE69518192D1 DE69518192T DE69518192T DE69518192D1 DE 69518192 D1 DE69518192 D1 DE 69518192D1 DE 69518192 T DE69518192 T DE 69518192T DE 69518192 T DE69518192 T DE 69518192T DE 69518192 D1 DE69518192 D1 DE 69518192D1
Authority
DE
Germany
Prior art keywords
sub
loweralkyl
preparation
hydrogen
pyridinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69518192T
Other languages
English (en)
Other versions
DE69518192T2 (de
Inventor
Thomas Bing Kin Lee
Keith E Goehring
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Aventis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharmaceuticals Inc filed Critical Aventis Pharmaceuticals Inc
Publication of DE69518192D1 publication Critical patent/DE69518192D1/de
Application granted granted Critical
Publication of DE69518192T2 publication Critical patent/DE69518192T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
DE69518192T 1994-05-13 1995-05-08 Verfahren zur Herstellung von N-Alkyl-N-Pyridinyl-1H-Indol-1-Aminen Expired - Lifetime DE69518192T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/242,395 US5459274A (en) 1994-05-13 1994-05-13 Preparation of N-alkyl-N-pyridinyl-1H-indol-1-amines

Publications (2)

Publication Number Publication Date
DE69518192D1 true DE69518192D1 (de) 2000-09-07
DE69518192T2 DE69518192T2 (de) 2001-05-31

Family

ID=22914624

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69518192T Expired - Lifetime DE69518192T2 (de) 1994-05-13 1995-05-08 Verfahren zur Herstellung von N-Alkyl-N-Pyridinyl-1H-Indol-1-Aminen

Country Status (11)

Country Link
US (3) US5459274A (de)
EP (1) EP0683165B1 (de)
JP (1) JP3816968B2 (de)
AT (1) ATE195120T1 (de)
AU (1) AU697090B2 (de)
CA (1) CA2149286A1 (de)
DE (1) DE69518192T2 (de)
DK (1) DK0683165T3 (de)
ES (1) ES2152342T3 (de)
GR (1) GR3034751T3 (de)
PT (1) PT683165E (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506903B1 (en) 1908-03-29 2003-01-14 Shionogi & Co., Ltd. Process for producing 4-thiazolylmethyl derivative
TWI243164B (en) * 2001-02-13 2005-11-11 Aventis Pharma Gmbh Acylated indanyl amines and their use as pharmaceuticals
GB0119435D0 (en) * 2001-02-15 2001-10-03 Aventis Pharm Prod Inc Method of treating of demyelinating diseases or conditions
WO2004014854A1 (en) * 2002-08-07 2004-02-19 Synaptic Pharmaceutical Corporation 3-imino-2-indolones for the treatment of depression and/or anxiety
US20040082615A1 (en) * 2002-08-07 2004-04-29 Michael Konkel 3-Imino-2-indolones for the treatement of depression and/or anxiety
AR046041A1 (es) * 2003-10-03 2005-11-23 Aventis Pharma Inc Procedimiento para la preparacion de compuestos heterociclicos n-amino sustituidos
FR2892021B1 (fr) * 2005-10-19 2008-01-04 Urogene Traitement de l'incontinence urinaire d'effort et mixte
FR2892022B1 (fr) * 2005-10-19 2008-01-04 Urogene Sa Traitement des symptomes de l'irritation de la vessie
FR2897614B1 (fr) * 2006-02-20 2008-05-23 Urogene Forme cristalline du chlorhydrate de la besipirdine, procedes de preparation et utilisations

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1458633A (en) * 1974-09-17 1976-12-15 Ici Ltd Process for dehalogenating aromatic compounds
JPS5687635A (en) * 1979-12-15 1981-07-16 Yoshikawa Kogyo Kk Forming method for protective covering layer of lance dipped in molten metal
US4692554A (en) * 1983-10-18 1987-09-08 Mitsui Toatsu Chemicals, Inc. Process for producing 1,3-bis(3-aminophenoxy)benzene
US4618686A (en) * 1984-09-27 1986-10-21 Ciba-Geigy Corporation Process for dehalogenation of aryl and alpha-araliphatic halides
US5032599A (en) * 1986-11-12 1991-07-16 Hoechst-Roussel Pharmaceuticals Inc. N-(pyrrol-l-yl)pyridinamines
US4752610A (en) * 1985-12-04 1988-06-21 Hoechst-Roussel Pharmaceuticals Inc. N-(pyrrol-1-yl)pyridinamines having memory enhancing properties
US5039811A (en) * 1987-04-24 1991-08-13 Hoechst-Roussel Pharmaceuticals Inc. Preparation of N-(pyridinyl)-1H-indol-1-amines
US4880822A (en) * 1987-04-24 1989-11-14 Hoechst-Roussel Pharmaceuticals, Inc. N-(pyridinyl)-1H-indol-1-amines
US4970218A (en) * 1987-04-24 1990-11-13 Hoechst-Roussel Pharmaceuticals Inc. N-(pyridinyl)-1H-indol-1-amines
ATE115143T1 (de) * 1987-04-24 1994-12-15 Hoechst Roussel Pharma N-(pyridinyl)-1h-indol-1-amine, verfahren zu deren herstellung und ihre verwendung als arzneimittel.
DK0415103T3 (da) * 1989-08-02 1995-06-19 Hoechst Roussel Pharma 2,3-Dihydro-1-(pyridinylamino)-indoler, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
US4983608A (en) * 1989-09-05 1991-01-08 Hoechst-Roussell Pharmaceuticals, Inc. N-substituted-4-pyrimidinamines and pyrimidinediamines
US5102891A (en) * 1990-07-23 1992-04-07 Hoechst-Roussel Pharmaceuticals Inc. 1-(substituted pyridinylamino)-1H-indol-5-yl substituted carbamates
US5319096A (en) * 1992-04-03 1994-06-07 Hoechst-Roussel Pharmaceuticals Inc. (1H-indol-1-yl)-2-(amino) acetamides and related (1H-indol-1-yl)-(aminoalkyl)amides, pharmaceutical composition and use
US5356910A (en) * 1993-07-19 1994-10-18 Hoechst-Roussel Pharmaceuticals Inc. Use of N-(pyridinyl)-1H-indol-1-amines for the treatment of obsessive-compulsive disorder

Also Published As

Publication number Publication date
EP0683165B1 (de) 2000-08-02
US5459274A (en) 1995-10-17
EP0683165A2 (de) 1995-11-22
EP0683165A3 (de) 1997-01-15
AU1799795A (en) 1995-11-23
CA2149286A1 (en) 1995-11-14
US5644062A (en) 1997-07-01
ES2152342T3 (es) 2001-02-01
PT683165E (pt) 2000-12-29
JPH07304768A (ja) 1995-11-21
JP3816968B2 (ja) 2006-08-30
US6512125B1 (en) 2003-01-28
GR3034751T3 (en) 2001-02-28
ATE195120T1 (de) 2000-08-15
DK0683165T3 (da) 2000-10-16
AU697090B2 (en) 1998-09-24
DE69518192T2 (de) 2001-05-31

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