DE69511448T2 - Verwendung von Phosphorsäurediester-Verbindungen zur Unterdrückung von Krebsmetastasen in der Leber - Google Patents

Verwendung von Phosphorsäurediester-Verbindungen zur Unterdrückung von Krebsmetastasen in der Leber

Info

Publication number
DE69511448T2
DE69511448T2 DE69511448T DE69511448T DE69511448T2 DE 69511448 T2 DE69511448 T2 DE 69511448T2 DE 69511448 T DE69511448 T DE 69511448T DE 69511448 T DE69511448 T DE 69511448T DE 69511448 T2 DE69511448 T2 DE 69511448T2
Authority
DE
Germany
Prior art keywords
phosphoric acid
acid diester
liver
diester compounds
cancer metastases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69511448T
Other languages
English (en)
Other versions
DE69511448D1 (de
Inventor
Tetsuya Toge
Toshihiro Hirai
Akihiro Yoshimoto
Kenichi Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Publication of DE69511448D1 publication Critical patent/DE69511448D1/de
Application granted granted Critical
Publication of DE69511448T2 publication Critical patent/DE69511448T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69511448T 1994-03-29 1995-03-24 Verwendung von Phosphorsäurediester-Verbindungen zur Unterdrückung von Krebsmetastasen in der Leber Expired - Fee Related DE69511448T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5867194 1994-03-29
JP24016794 1994-10-04

Publications (2)

Publication Number Publication Date
DE69511448D1 DE69511448D1 (de) 1999-09-23
DE69511448T2 true DE69511448T2 (de) 2000-04-27

Family

ID=26399697

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69511448T Expired - Fee Related DE69511448T2 (de) 1994-03-29 1995-03-24 Verwendung von Phosphorsäurediester-Verbindungen zur Unterdrückung von Krebsmetastasen in der Leber

Country Status (7)

Country Link
US (1) US5552389A (de)
EP (1) EP0674904B1 (de)
KR (1) KR950032257A (de)
AT (1) ATE183394T1 (de)
CA (1) CA2145229A1 (de)
DE (1) DE69511448T2 (de)
ES (1) ES2134409T3 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR549901A0 (en) 2001-06-06 2001-07-12 Vital Health Sciences Pty Ltd Topical formulation containing tocopheryl phosphates
AU2002303210A1 (en) 2001-04-06 2002-10-21 Cytorex Biosciences, Inc. Pharmacologically active strong acid solutions
AU2002317053B2 (en) 2001-07-27 2004-08-05 Vital Health Sciences Pty Ltd Dermal therapy using phosphate derivatives of electron transfer agents
AU2002950713A0 (en) 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
EP1720551B9 (de) 2004-03-03 2011-09-21 Vital Health Sciences Pty Ltd. Alkaloid-formulierungen
KR20070108383A (ko) * 2005-03-03 2007-11-09 바이탈 헬스 사이언시즈 피티와이 리미티드 지질 저하성 화합물
AU2006220247B2 (en) * 2005-03-03 2011-08-25 Vital Health Sciences Pty Ltd Compounds having anti-cancer properties
WO2006092024A1 (en) * 2005-03-03 2006-09-08 Vital Health Sciences Pty Ltd Compounds having anti-cancer properties
EP1893159B1 (de) 2005-06-17 2015-09-30 Vital Health Sciences Pty Ltd. Träger umfassend ein oder mehrere di- und/oder monophosphatderivate von elektronentransfermitteln
EP2531047A4 (de) 2010-02-05 2014-03-19 Phosphagenics Ltd Träger mit einem nichtneutralisierten tocopherylphosphat
ES2829386T3 (es) 2010-03-30 2021-05-31 Phosphagenics Ltd Parche de administración transdérmica
WO2012122586A1 (en) 2011-03-15 2012-09-20 Phosphagenics Limited New composition
CN108601732A (zh) 2015-12-09 2018-09-28 磷肌酸有限公司 药物制剂
MX2019006845A (es) 2016-12-21 2019-10-15 Avecho Biotechnology Ltd Proceso.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62145019A (ja) * 1985-12-19 1987-06-29 Senjiyu Seiyaku Kk 抗炎症剤
JPH02229169A (ja) * 1989-03-01 1990-09-11 Takeda Chem Ind Ltd ピラゾロン誘導体
JPH02229168A (ja) * 1989-03-01 1990-09-11 Takeda Chem Ind Ltd ピラゾロン誘導体

Also Published As

Publication number Publication date
ES2134409T3 (es) 1999-10-01
DE69511448D1 (de) 1999-09-23
US5552389A (en) 1996-09-03
CA2145229A1 (en) 1995-09-30
KR950032257A (ko) 1995-12-20
ATE183394T1 (de) 1999-09-15
EP0674904A1 (de) 1995-10-04
EP0674904B1 (de) 1999-08-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee