DE69507887D1 - Verfahren zur herstellung von n-biphenylmethylthiadiazolin derivaten oder deren salzen sowie dafür benötigte zwischen verbindungen - Google Patents

Verfahren zur herstellung von n-biphenylmethylthiadiazolin derivaten oder deren salzen sowie dafür benötigte zwischen verbindungen

Info

Publication number
DE69507887D1
DE69507887D1 DE69507887T DE69507887T DE69507887D1 DE 69507887 D1 DE69507887 D1 DE 69507887D1 DE 69507887 T DE69507887 T DE 69507887T DE 69507887 T DE69507887 T DE 69507887T DE 69507887 D1 DE69507887 D1 DE 69507887D1
Authority
DE
Germany
Prior art keywords
biphenylmethylthiadiazoline
producing
derivatives
salts
intermediate compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69507887T
Other languages
English (en)
Other versions
DE69507887T2 (de
Inventor
Satoshi Wakanuga Seiyaku Inoue
Nobuya Wakunaga Seiyaku Sakae
Masaharu Wakunaga Sei Yokomoto
Kouji Wakunaga Seiya Nishimura
Terukage Wakunaga Seiya Hirata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wakunaga Pharmaceutical Co Ltd
Original Assignee
Wakunaga Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wakunaga Pharmaceutical Co Ltd filed Critical Wakunaga Pharmaceutical Co Ltd
Publication of DE69507887D1 publication Critical patent/DE69507887D1/de
Application granted granted Critical
Publication of DE69507887T2 publication Critical patent/DE69507887T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69507887T 1994-09-20 1995-09-19 Verfahren zur herstellung von n-biphenylmethylthiadiazolin derivaten oder deren salzen sowie dafür benötigte zwischen verbindungen Expired - Fee Related DE69507887T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP22443994 1994-09-20
JP31813194 1994-12-21
PCT/JP1995/001866 WO1996009301A1 (fr) 1994-09-20 1995-09-19 Procede de production d'un derive de n-biphenylmethylthiadiazoline ou un sel de celui-ci et son intermediaire de production

Publications (2)

Publication Number Publication Date
DE69507887D1 true DE69507887D1 (de) 1999-03-25
DE69507887T2 DE69507887T2 (de) 1999-06-17

Family

ID=26526062

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69507887T Expired - Fee Related DE69507887T2 (de) 1994-09-20 1995-09-19 Verfahren zur herstellung von n-biphenylmethylthiadiazolin derivaten oder deren salzen sowie dafür benötigte zwischen verbindungen

Country Status (8)

Country Link
US (1) US5965738A (de)
EP (1) EP0782996B1 (de)
AT (1) ATE176784T1 (de)
DE (1) DE69507887T2 (de)
DK (1) DK0782996T3 (de)
ES (1) ES2129850T3 (de)
GR (1) GR3029836T3 (de)
WO (1) WO1996009301A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE169014T1 (de) * 1994-02-10 1998-08-15 Wakunaga Seiyaku Kk Kaliumsalz eines biphenylmethanderivates und dasselbe enthaltendes medikament
CA2224643A1 (en) * 1995-06-27 1997-01-16 Kouji Nishimura Process for producing tetrazolylated biphenylmethane derivatives
GB0222056D0 (en) * 2002-09-23 2002-10-30 Novartis Ag Process for the manufacture of organic compounds
ES2281312T3 (es) * 2003-01-16 2008-08-01 Teva Pharmaceutical Industries Ltd. Nueva sintesis de irbesartan.
US7939501B2 (en) * 2003-04-15 2011-05-10 Smith Francis X Ophthalmic and contact lens solutions containing peptides as preservative
MXPA06001485A (es) * 2003-08-08 2006-05-15 Dipharma Spa Procedimiento para la preparacion de derivados de feniltetrazol.
ES2251292B1 (es) 2004-04-20 2007-07-01 Inke, S.A. Procedimiento para la obtencion de un compuesto farmaceuticamente activo y de sus intermedios de sintesis.
ITMI20051989A1 (it) * 2005-10-20 2007-04-21 Dipharma Spa Procedimerntyo per la preparazione di composti antagonisti di angiotensina ii
ES2302671T1 (es) * 2006-08-29 2008-08-01 Teva Pharmaceutical Industries Ltd. Procedimientos para la sintesis de 5-fenil-1-tritil-1h-tetrazol.

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
US5039814A (en) * 1990-05-02 1991-08-13 Merck & Co., Inc. Ortho-lithiation process for the synthesis of 2-substituted 1-(tetrazol-5-yl)benzenes
US5290780A (en) * 1991-01-30 1994-03-01 American Cyanamid Co. Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
US5206235A (en) * 1991-03-20 1993-04-27 Merck & Co., Inc. Benzo-fused lactams that promote the release of growth hormone
TW226375B (de) * 1991-10-24 1994-07-11 American Home Prod
KR100212257B1 (ko) * 1991-11-18 1999-08-02 미리암 디. 메코나헤이 Aii 수용체 길항물질을 합성하기 위한 테트라졸릴페닐보론산 중간체의 제조 방법
FR2688781B1 (fr) * 1992-03-23 1994-07-01 Sanofi Elf Imidazolines n-substituees par un groupement biphenylmethyle, leur preparation, les compositions pharmaceutiques en contenant.
DE4218157A1 (de) * 1992-06-02 1993-12-09 Bayer Ag Thiadiazoline
US5310929A (en) * 1992-08-06 1994-05-10 E. I. Du Pont De Nemours And Company Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists
EP0656355A1 (de) * 1992-08-11 1995-06-07 Wakunaga Seiyaku Kabushiki Kaisha Biphenylmethanderivate und sie enthaltende medikamente
US5654322A (en) * 1992-08-11 1997-08-05 Wakunaga Seiyaku Kabushiki Kaisha Biphenylmethane derivatives and pharmaceuticals containing the same
US5317017A (en) * 1992-09-30 1994-05-31 Merck & Co., Inc. N-biphenyl-3-amido substituted benzolactams stimulate growth hormone release
EP0736021A4 (de) * 1993-12-23 1997-04-02 Merck & Co Inc Polymorphe von losartan und verfahren zur herstellung von form ii losartan
ATE169014T1 (de) * 1994-02-10 1998-08-15 Wakunaga Seiyaku Kk Kaliumsalz eines biphenylmethanderivates und dasselbe enthaltendes medikament

Also Published As

Publication number Publication date
EP0782996A1 (de) 1997-07-09
GR3029836T3 (en) 1999-06-30
US5965738A (en) 1999-10-12
DK0782996T3 (da) 1999-09-20
EP0782996B1 (de) 1999-02-17
EP0782996A4 (de) 1997-11-05
ES2129850T3 (es) 1999-06-16
DE69507887T2 (de) 1999-06-17
WO1996009301A1 (fr) 1996-03-28
ATE176784T1 (de) 1999-03-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee