DE69429512T2 - Thermoresistente alpha-1-antitrypsinmütante - Google Patents

Thermoresistente alpha-1-antitrypsinmütante

Info

Publication number
DE69429512T2
DE69429512T2 DE69429512T DE69429512T DE69429512T2 DE 69429512 T2 DE69429512 T2 DE 69429512T2 DE 69429512 T DE69429512 T DE 69429512T DE 69429512 T DE69429512 T DE 69429512T DE 69429512 T2 DE69429512 T2 DE 69429512T2
Authority
DE
Germany
Prior art keywords
thermor
resistant alpha
antitrypsin mutant
antitrypsin
mutant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69429512T
Other languages
English (en)
Other versions
DE69429512D1 (en
Inventor
Myeong-Hee Yu
Ki-Sun Kwon
Kee Nyung Lee
Hwa Soo Shin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea Green Cross Corp
Korea Institute of Science and Technology KIST
Original Assignee
Korea Green Cross Corp
Korea Institute of Science and Technology KIST
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Green Cross Corp, Korea Institute of Science and Technology KIST filed Critical Korea Green Cross Corp
Publication of DE69429512D1 publication Critical patent/DE69429512D1/de
Application granted granted Critical
Publication of DE69429512T2 publication Critical patent/DE69429512T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8125—Alpha-1-antitrypsin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69429512T 1993-05-18 1994-05-17 Thermoresistente alpha-1-antitrypsinmütante Expired - Fee Related DE69429512T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR930008510 1993-05-18
PCT/KR1994/000048 WO1994026781A1 (en) 1993-05-18 1994-05-17 Thermoresistant alpha-1-antitrypsin mutein

Publications (2)

Publication Number Publication Date
DE69429512D1 DE69429512D1 (en) 2002-01-31
DE69429512T2 true DE69429512T2 (de) 2002-08-01

Family

ID=19355555

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69429512T Expired - Fee Related DE69429512T2 (de) 1993-05-18 1994-05-17 Thermoresistente alpha-1-antitrypsinmütante

Country Status (6)

Country Link
US (1) US5817484A (de)
EP (1) EP0701570B1 (de)
JP (1) JP2768557B2 (de)
CA (1) CA2163081C (de)
DE (1) DE69429512T2 (de)
WO (1) WO1994026781A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2318732A (en) 1996-11-01 1998-05-06 Johnson & Johnson Medical Wound healing compositions containing alpha-1-antitrypsin
US6849605B1 (en) * 1999-03-05 2005-02-01 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of viral infections
AU3731400A (en) 1999-03-05 2000-09-21 Trustees Of University Technology Corporation, The Methods and compositions useful in inhibiting apoptosis
US6489308B1 (en) 1999-03-05 2002-12-03 Trustees Of University Of Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of nitric-oxide-induced clinical conditions
WO2000051625A1 (en) * 1999-03-05 2000-09-08 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of herpes viruses
PT1303265E (pt) 2000-07-20 2007-10-09 Lauras As ''utilização de inibidores da cox-2 como imuno-estimulantes, no tratamento do vih ou da sida''
US20040220242A1 (en) * 2003-05-02 2004-11-04 Leland Shapiro Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide induced clinical conditions
KR100992526B1 (ko) 2007-11-21 2010-11-05 한국과학기술연구원 이황화결합을 이용한 내열성의 알파-1-안티트립신 뮤테인및 그의 제조방법
KR101402702B1 (ko) * 2011-09-15 2014-06-05 (주)알테오젠 신규한 알파-1 안티트립신 변이체, 이의 제조방법 및 용도
WO2023083859A1 (en) 2021-11-09 2023-05-19 Danmarks Tekniske Universitet Variants of alpha-1-antitrypsin

Also Published As

Publication number Publication date
CA2163081A1 (en) 1994-11-24
JP2768557B2 (ja) 1998-06-25
JPH08509865A (ja) 1996-10-22
US5817484A (en) 1998-10-06
EP0701570B1 (de) 2001-12-19
CA2163081C (en) 2000-03-14
DE69429512D1 (en) 2002-01-31
EP0701570A1 (de) 1996-03-20
WO1994026781A1 (en) 1994-11-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee