DE69426568T2 - Verfahren zur umhüllung von nanopartikeln oder -tröpfchen - Google Patents

Verfahren zur umhüllung von nanopartikeln oder -tröpfchen

Info

Publication number
DE69426568T2
DE69426568T2 DE69426568T DE69426568T DE69426568T2 DE 69426568 T2 DE69426568 T2 DE 69426568T2 DE 69426568 T DE69426568 T DE 69426568T DE 69426568 T DE69426568 T DE 69426568T DE 69426568 T2 DE69426568 T2 DE 69426568T2
Authority
DE
Germany
Prior art keywords
solvent
polymer
droplets
preparing
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69426568T
Other languages
English (en)
Other versions
DE69426568D1 (de
Inventor
Mas Jose Alberto Vallet
Valdivia Francisco Javie Galan
Perdiguer Nuria Carreras
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Cusi SA
Original Assignee
Alcon Cusi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Cusi SA filed Critical Alcon Cusi SA
Application granted granted Critical
Publication of DE69426568D1 publication Critical patent/DE69426568D1/de
Publication of DE69426568T2 publication Critical patent/DE69426568T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • B01J13/22—Coating
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/788—Of specified organic or carbon-based composition
    • Y10S977/795—Composed of biological material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/89—Deposition of materials, e.g. coating, cvd, or ald
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/89—Deposition of materials, e.g. coating, cvd, or ald
    • Y10S977/891—Vapor phase deposition
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)
  • Luminescent Compositions (AREA)
  • Paints Or Removers (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Glanulating (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69426568T 1994-05-20 1994-09-30 Verfahren zur umhüllung von nanopartikeln oder -tröpfchen Expired - Fee Related DE69426568T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09401121A ES2078190B1 (es) 1994-05-20 1994-05-20 Procedimiento para el recubrimiento de goticulas o particulas de tamaño nanometrico.
PCT/ES1994/000085 WO1995031975A1 (es) 1994-05-20 1994-09-30 Procedimiento para el recubrimiento de goticulas o particulas de tamaño nanometrico

Publications (2)

Publication Number Publication Date
DE69426568D1 DE69426568D1 (de) 2001-02-15
DE69426568T2 true DE69426568T2 (de) 2001-08-23

Family

ID=8286348

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69426568T Expired - Fee Related DE69426568T2 (de) 1994-05-20 1994-09-30 Verfahren zur umhüllung von nanopartikeln oder -tröpfchen

Country Status (22)

Country Link
US (1) US5851452A (de)
EP (1) EP0717989B1 (de)
JP (1) JPH09501101A (de)
KR (1) KR960703577A (de)
CN (1) CN1130868A (de)
AT (1) ATE198548T1 (de)
AU (1) AU696400B2 (de)
BG (1) BG100372A (de)
BR (1) BR9407333A (de)
CA (1) CA2167681A1 (de)
DE (1) DE69426568T2 (de)
DK (1) DK0717989T3 (de)
ES (1) ES2078190B1 (de)
FI (1) FI961348A0 (de)
GR (1) GR3035655T3 (de)
HK (1) HK1017807A1 (de)
HU (1) HU9600386D0 (de)
NO (1) NO960232L (de)
OA (1) OA10257A (de)
PL (1) PL312666A1 (de)
PT (1) PT717989E (de)
WO (1) WO1995031975A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922403A (en) * 1996-03-12 1999-07-13 Tecle; Berhan Method for isolating ultrafine and fine particles
US5945126A (en) * 1997-02-13 1999-08-31 Oakwood Laboratories L.L.C. Continuous microsphere process
EP1023050B1 (de) * 1997-06-27 2013-09-25 Abraxis BioScience, LLC Zusammensetzungen von pharmakologischen wirkstoffen, verfahren zu deren herstellung und deren verwendung
CA2352362C (en) * 1998-11-30 2009-02-17 Nanosphere, Inc. Nanoparticles with polymer shells
DE19856432A1 (de) * 1998-12-08 2000-06-15 Basf Ag Nanopartikuläre Kern-Schale Systeme sowie deren Verwendung in pharmazeutischen und kosmetischen Zubereitungen
FR2805761B1 (fr) * 2000-03-02 2002-08-30 Mainelab Nanocapsules lipidiques, procede de preparation et utilisation comme medicament
WO2003037359A1 (fr) * 2001-10-29 2003-05-08 Chengdu Somo Namotechnology Co., Ltd. Nanoparticule de composants de medicaments insolubles et procede de production correspondant
US7053034B2 (en) * 2002-04-10 2006-05-30 Salvona, Llc Targeted controlled delivery compositions activated by changes in pH or salt concentration
DE602004019662D1 (de) 2003-09-26 2009-04-09 3M Innovative Properties Co Nanoskalige goldkatalysatoren, aktivierungsmittel, trägermedien und verwandte methodologien zur herstellung derartiger katalysatorsysteme, insbesondere bei abscheidung des golds auf den trägermedien mittels pvd
US8058202B2 (en) * 2005-01-04 2011-11-15 3M Innovative Properties Company Heterogeneous, composite, carbonaceous catalyst system and methods that use catalytically active gold
KR101430767B1 (ko) * 2005-07-18 2014-08-19 유니버시티 오브 메사츄세츠 로웰 나노에멀젼 조성물 및 이의 제조 및 사용 방법
PT3295955T (pt) 2005-12-01 2021-07-12 Univ Massachusetts Lowell Nanoemulsões botulínicas
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
WO2008070538A2 (en) 2006-12-01 2008-06-12 Anterios, Inc. Micellar nanoparticles comprising botulinum toxin
CN107080703A (zh) 2006-12-01 2017-08-22 安特里奥公司 肽纳米粒子和其用途
EP2162117B1 (de) 2007-05-31 2018-02-21 Anterios, Inc. Nukleinsäure-nanoteilchen und ihre verwendungszwecke
WO2011088273A2 (en) 2010-01-13 2011-07-21 Dohrmann Daniel R Ultra-low flow agricultural pump with unobstructed flow path and electronic flow control, tank refill indication, and detection of loss of flow
BR102015032910B1 (pt) * 2015-12-29 2021-03-09 Companhia Nitro Química Brasileira processo de obtenção de uma dispersão coloidal, dispersão coloidal e seu uso
CA3034527A1 (en) 2016-08-23 2018-03-01 Emmanuel John Simons Compositions and methods for treating non-age-associated hearing impairment in a human subject
MX2019005833A (es) 2016-11-21 2019-10-30 Eirion Therapeutics Inc Administracion transdermica de agentes grandes.
CN110325272A (zh) * 2017-03-28 2019-10-11 富士胶片株式会社 微胶囊及其制造方法
US20200001263A1 (en) * 2018-06-28 2020-01-02 Cornell University Encapsulation System and Method
CN116096905A (zh) 2020-02-21 2023-05-09 阿库斯股份有限公司 用于治疗人受试者的非年龄相关性听力损伤的组合物和方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2909906A1 (de) * 1979-03-14 1980-10-02 Bayer Ag Verfahren zur kontinuierlichen herstellung von mikrokapseln
CH656884A5 (de) * 1983-08-26 1986-07-31 Sandoz Ag Polyolester, deren herstellung und verwendung.
FR2608988B1 (fr) * 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules
FR2608942B1 (fr) * 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanocapsules
US5021248A (en) * 1988-09-19 1991-06-04 Enzytech, Inc. Hydrophobic protein microparticles and preparation thereof
FR2663222A1 (fr) * 1990-06-13 1991-12-20 Medgenix Group Sa Microcapsule de liquide huileux.
KR930006431B1 (ko) * 1990-10-11 1993-07-16 재단법인 한국화학연구소 약물의 미세캡슐화 방법
ES2034891B1 (es) * 1991-08-08 1993-12-16 Cusi Lab Procedimiento de elaboracion en continuo de sistemas coloidales dispersos, en forma de nanocapsulas o nanoparticulas.
US5326488A (en) * 1992-02-18 1994-07-05 Idemitsu Kosan Co., Ltd. Mannich reaction product and process for producing the same and use of the product
ATE170293T1 (de) * 1992-06-08 1998-09-15 Behring Diagnostics Inc Flüssigkeitsspendersystem
FR2692167B1 (fr) * 1992-06-16 1994-09-16 Centre Nat Rech Scient Préparation et application de nouveaux systèmes colloïdaux nanovésiculaires dispersibles à base de cyclodextrine, sous forme de nanocapsules.

Also Published As

Publication number Publication date
BG100372A (en) 1996-12-31
GR3035655T3 (en) 2001-06-29
ES2078190B1 (es) 1996-08-01
HK1017807A1 (en) 1999-11-26
HU9600386D0 (en) 1996-04-29
ATE198548T1 (de) 2001-01-15
AU7537994A (en) 1995-12-18
EP0717989B1 (de) 2001-01-10
PL312666A1 (en) 1996-04-29
KR960703577A (ko) 1996-08-31
JPH09501101A (ja) 1997-02-04
NO960232L (no) 1996-03-19
CA2167681A1 (en) 1995-11-30
CN1130868A (zh) 1996-09-11
AU696400B2 (en) 1998-09-10
DE69426568D1 (de) 2001-02-15
FI961348A (fi) 1996-03-25
DK0717989T3 (da) 2001-05-21
FI961348A0 (fi) 1996-03-25
OA10257A (en) 1997-10-07
WO1995031975A1 (es) 1995-11-30
US5851452A (en) 1998-12-22
NO960232D0 (no) 1996-01-19
PT717989E (pt) 2001-06-29
EP0717989A1 (de) 1996-06-26
ES2078190A1 (es) 1995-12-01
BR9407333A (pt) 1996-06-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee