DE69419640D1 - Pharmakologische Verwendung von 5-Aminophthaloylhydrazide; ihre Zusammensetzung und Anwendung - Google Patents

Pharmakologische Verwendung von 5-Aminophthaloylhydrazide; ihre Zusammensetzung und Anwendung

Info

Publication number
DE69419640D1
DE69419640D1 DE69419640T DE69419640T DE69419640D1 DE 69419640 D1 DE69419640 D1 DE 69419640D1 DE 69419640 T DE69419640 T DE 69419640T DE 69419640 T DE69419640 T DE 69419640T DE 69419640 D1 DE69419640 D1 DE 69419640D1
Authority
DE
Germany
Prior art keywords
aminophthaloylhydrazide
composition
application
pharmacological use
pertains
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69419640T
Other languages
English (en)
Inventor
Lonid Minin
Slava Saizev
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MEDINKOR ZMM AG
Original Assignee
MEDINKOR ZMM AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MEDINKOR ZMM AG filed Critical MEDINKOR ZMM AG
Application granted granted Critical
Publication of DE69419640D1 publication Critical patent/DE69419640D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69419640T 1993-02-19 1994-02-12 Pharmakologische Verwendung von 5-Aminophthaloylhydrazide; ihre Zusammensetzung und Anwendung Expired - Lifetime DE69419640D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH530/93A CH683965A5 (it) 1993-02-19 1993-02-19 Composti della classe dei ftalidrazidici come sostanza attiva in agenti antinfiammatori ed antitossici.

Publications (1)

Publication Number Publication Date
DE69419640D1 true DE69419640D1 (de) 1999-09-02

Family

ID=4189123

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69419640T Expired - Lifetime DE69419640D1 (de) 1993-02-19 1994-02-12 Pharmakologische Verwendung von 5-Aminophthaloylhydrazide; ihre Zusammensetzung und Anwendung

Country Status (6)

Country Link
US (1) US5543410A (de)
EP (1) EP0617024B1 (de)
JP (1) JP2693373B2 (de)
AT (1) ATE182586T1 (de)
CH (1) CH683965A5 (de)
DE (1) DE69419640D1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA004056B1 (ru) 2000-03-28 2003-12-25 Муса Тажудинович Абидов Лекарственный препарат и способ его получения
US6953799B1 (en) * 2002-10-30 2005-10-11 Bach Pharma, Inc. Modulation of cell fates and activities by diketo phthalazines
US7326690B2 (en) * 2002-10-30 2008-02-05 Bach Pharma, Inc. Modulation of cell fates and activities by phthalazinediones
WO2005012309A1 (en) * 2003-08-04 2005-02-10 Valery Khazhmuratovich Zhilov Cyclic bioisosters of purine system derivatives and a pharmaceutical composition based thereon
BRPI0512526A (pt) * 2004-06-23 2008-03-11 Synta Pharmaceuticals Corp composto, composição farmacêutica, método para tratar um paciente com cáncer e método para preparar um di-sal de bis(tio-hidrazida amida)
EP2393361B1 (de) * 2009-02-06 2016-12-07 Bach Pharma, Inc. Pharmazeutisch reine phthalazindione, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
US8895555B2 (en) 2009-02-19 2014-11-25 Bach Pharma, Inc. Methods of treating intestinal diseases and inflammatory conditions related to HIV-AIDS
AT509045B1 (de) * 2010-01-29 2011-06-15 Planta Naturstoffe Vertriebsges M B H Verbindungen zur behandlung von asthma bronchiale
AU2011223226B2 (en) 2010-03-01 2015-04-23 Metriopharm Ag Crystalline forms for 5-amino-2,3-dihydrophthalazine-1,4-dione sodium salt, pharmaceutical preparations containing the same and method for the production of said forms
WO2012127441A1 (en) * 2011-03-23 2012-09-27 Semorex Technologies Ltd. Treatment of proliferative disorders with a chemiluminescent agent
RU2577849C2 (ru) * 2013-09-25 2016-03-20 Общество с ограниченной ответственностью "Сэлвим" Бис(5-амино-1,4-диоксо-1,2,3,4-тетрагидрофталазин-2-ил)цинк, способ его получения, фармацевтическая композиция на его основе, лечебные средства на его основе, способ лечения кожных заболеваний и способ лечения гастрита
ES2753577T3 (es) 2014-12-18 2020-04-13 Metriopharm Ag Forma cristalina de 5-amino-2,3-dihidroftalazina-1,4-diona sal sódica, los preparados farmacéuticos que la contengan y método de producción
EP3248602A1 (de) * 2016-05-26 2017-11-29 MetrioPharm AG Verwendung von 5-amino-2,3-dihydro-1,4-phthalazindion bei der behandlung von entzündlichen und/oder degenerativen erkrankungen der sehnen, gelenkbänder, gelenkkapseln und schleimbeutel
EP3858358A1 (de) * 2020-01-31 2021-08-04 MetrioPharm AG Verwendung von 5-amino-2,3-dihydro-1,4-phthalazindion zur behandlung von seltenen chronischen entzündlichen lungenerkrankungen

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2453578A (en) * 1944-02-19 1948-11-09 American Cyanamid Co Preparation of chemiluminescent composition of matter
GB1100911A (en) * 1963-08-20 1968-01-24 Benger Lab Ltd Phthalazine derivatives
GB1293565A (en) * 1969-05-03 1972-10-18 Aspro Nicholas Ltd Aminophthalazines and pharmaceutical compositions thereof
JPS5116430B2 (de) * 1971-08-05 1976-05-24
JPS5023689B2 (de) * 1971-11-29 1975-08-09
US3957776A (en) * 1973-02-28 1976-05-18 Delmar Chemicals Limited Novel phthalazinone compounds
US4011219A (en) * 1975-03-28 1977-03-08 Chugai Seiyaku Kabushiki Kaisha Phthalazine derivatives and salts thereof
IE47592B1 (en) * 1977-12-29 1984-05-02 Ici Ltd Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
US4226993A (en) * 1978-07-24 1980-10-07 Miles Laboratories, Inc. Amino-functionalized phthalhydrazides
US4355165A (en) * 1978-07-24 1982-10-19 Miles Laboratories, Inc. Amino-functionalized phthalhydrazide intermediates
US4334069A (en) * 1978-07-24 1982-06-08 Miles Laboratories, Inc. Chemiluminescent phthalhydrazide-labeled hapten conjugates
US4250180A (en) * 1979-07-16 1981-02-10 Ortho Pharmaceutical Corporation Method of treating arrhythmia
JPS57501234A (de) * 1980-08-25 1982-07-15
HU181184B (en) * 1980-09-12 1983-06-28 Eszakmagyar Vegyimuevek Composition for replacing kinetine,the effect and membraneactivity of which is similar to citokinine,which composition improves plant productivity,quantity of protein-nitrogen and anion-absorptivity
US4440763A (en) * 1981-03-18 1984-04-03 Block Drug Company, Inc. Use of 4-aminosalicyclic acid as an anti-inflammatory agent
US4665181A (en) * 1984-05-17 1987-05-12 Pennwalt Corporation Anti-inflammatory phthalazinones
US5391555A (en) * 1991-11-12 1995-02-21 Miles Inc. Methods for treating inflammatory bowel disease with leukotriene synthesis inhibitors
CH683966A5 (it) * 1993-02-19 1994-06-30 Limad Marketing Exp & Imp Composti della classe dei ftalidrazidici come sostanze attive in agenti anti-ipossici e di difesa.

Also Published As

Publication number Publication date
JP2693373B2 (ja) 1997-12-24
US5543410A (en) 1996-08-06
JPH07179431A (ja) 1995-07-18
CH683965A5 (it) 1994-06-30
ATE182586T1 (de) 1999-08-15
EP0617024B1 (de) 1999-07-28
EP0617024A1 (de) 1994-09-28

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