ATE182586T1 - Pharmakologische verwendung von 5- aminophthaloylhydrazide; ihre zusammensetzung und anwendung - Google Patents
Pharmakologische verwendung von 5- aminophthaloylhydrazide; ihre zusammensetzung und anwendungInfo
- Publication number
- ATE182586T1 ATE182586T1 AT94102183T AT94102183T ATE182586T1 AT E182586 T1 ATE182586 T1 AT E182586T1 AT 94102183 T AT94102183 T AT 94102183T AT 94102183 T AT94102183 T AT 94102183T AT E182586 T1 ATE182586 T1 AT E182586T1
- Authority
- AT
- Austria
- Prior art keywords
- aminophthhaloylhydrazide
- composition
- application
- pharmacological use
- pertains
- Prior art date
Links
- 230000000144 pharmacologic effect Effects 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001147 anti-toxic effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH530/93A CH683965A5 (it) | 1993-02-19 | 1993-02-19 | Composti della classe dei ftalidrazidici come sostanza attiva in agenti antinfiammatori ed antitossici. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE182586T1 true ATE182586T1 (de) | 1999-08-15 |
Family
ID=4189123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94102183T ATE182586T1 (de) | 1993-02-19 | 1994-02-12 | Pharmakologische verwendung von 5- aminophthaloylhydrazide; ihre zusammensetzung und anwendung |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5543410A (de) |
| EP (1) | EP0617024B1 (de) |
| JP (1) | JP2693373B2 (de) |
| AT (1) | ATE182586T1 (de) |
| CH (1) | CH683965A5 (de) |
| DE (1) | DE69419640D1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2160104C2 (ru) * | 1997-11-06 | 2000-12-10 | Закрытое акционерное общество "Центр современной медицины "Медикор" | Способ лечения язвенной болезни и лекарственный препарат для его осуществления |
| AU4291201A (en) | 2000-03-28 | 2001-10-08 | Musa Tazhudinovich Abidov | A medicament and method for the production thereof |
| RU2211036C2 (ru) * | 2001-11-20 | 2003-08-27 | Общество с ограниченной ответственностью "Абидофарма" | Лекарственный препарат (варианты) и способ его производства |
| US6953799B1 (en) * | 2002-10-30 | 2005-10-11 | Bach Pharma, Inc. | Modulation of cell fates and activities by diketo phthalazines |
| US7326690B2 (en) * | 2002-10-30 | 2008-02-05 | Bach Pharma, Inc. | Modulation of cell fates and activities by phthalazinediones |
| RU2302863C2 (ru) * | 2003-04-18 | 2007-07-20 | Общество с ограниченной ответственностью "Абидофарма" | Лекарственный препарат (варианты) |
| RU2326870C2 (ru) * | 2003-08-04 | 2008-06-20 | Валерий Хажмуратович ЖИЛОВ | Применение циклических биоизостеров производных пуриновой системы для лечения расстройств, вызванных нарушениями нитрергической и дофаминергической систем |
| EP1655301B1 (de) | 2003-08-04 | 2015-03-11 | Valery Khazhmuratovich Zhilov | Cyclische bioisostere von purinsystemderivaten und darauf basierende pharmazeutische zusammensetzung |
| RU2406722C2 (ru) * | 2004-06-23 | 2010-12-20 | Синта Фармасьютикалс Корп. | Соли бис-(тиогидразидамида) для лечения рака |
| EP2393361B1 (de) * | 2009-02-06 | 2016-12-07 | Bach Pharma, Inc. | Pharmazeutisch reine phthalazindione, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen |
| WO2010096686A1 (en) * | 2009-02-19 | 2010-08-26 | Bach Pharma, Inc. | Methods of treating intestinal diseases and inflammatory conditions related to hiv-aids |
| AT509045B1 (de) * | 2010-01-29 | 2011-06-15 | Planta Naturstoffe Vertriebsges M B H | Verbindungen zur behandlung von asthma bronchiale |
| CN102971300B (zh) * | 2010-03-01 | 2016-03-02 | 梅特里奥药品股份公司 | 5-氨基-2,3-二氢-(2,3-二氮杂萘)-1,4-二酮钠盐的晶型、含有它们的药物制剂以及所述晶型的生产方法 |
| CA2829755A1 (en) | 2011-03-23 | 2012-09-27 | Semorex Technologies Ltd. | Treatment of proliferative disorders with a chemiluminescent agent |
| RU2577849C2 (ru) * | 2013-09-25 | 2016-03-20 | Общество с ограниченной ответственностью "Сэлвим" | Бис(5-амино-1,4-диоксо-1,2,3,4-тетрагидрофталазин-2-ил)цинк, способ его получения, фармацевтическая композиция на его основе, лечебные средства на его основе, способ лечения кожных заболеваний и способ лечения гастрита |
| US10258620B2 (en) | 2014-12-18 | 2019-04-16 | Metriopharm Ag | Crystalline form of 5-amino-2,3-dihydrophthalazine-1,4-dione sodium salt, pharmaceutical preparations containing the same and method for the production of said form |
| EP3248602A1 (de) * | 2016-05-26 | 2017-11-29 | MetrioPharm AG | Verwendung von 5-amino-2,3-dihydro-1,4-phthalazindion bei der behandlung von entzündlichen und/oder degenerativen erkrankungen der sehnen, gelenkbänder, gelenkkapseln und schleimbeutel |
| US20210379063A1 (en) * | 2018-10-26 | 2021-12-09 | Immunopharma Plus D.O.O. | Oral aminodihydrophthalazinedione compositions and their use in the treatment of non-viral hepatitis |
| EP3858358A1 (de) * | 2020-01-31 | 2021-08-04 | MetrioPharm AG | Verwendung von 5-amino-2,3-dihydro-1,4-phthalazindion zur behandlung von seltenen chronischen entzündlichen lungenerkrankungen |
| RU2747467C1 (ru) * | 2020-07-17 | 2021-05-05 | Муса Тажудинович Абидов | Способ защиты от коронавирусной инфекции |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2453578A (en) * | 1944-02-19 | 1948-11-09 | American Cyanamid Co | Preparation of chemiluminescent composition of matter |
| GB1100911A (en) * | 1963-08-20 | 1968-01-24 | Benger Lab Ltd | Phthalazine derivatives |
| GB1293565A (en) * | 1969-05-03 | 1972-10-18 | Aspro Nicholas Ltd | Aminophthalazines and pharmaceutical compositions thereof |
| JPS5116430B2 (de) * | 1971-08-05 | 1976-05-24 | ||
| JPS5023689B2 (de) * | 1971-11-29 | 1975-08-09 | ||
| US3957776A (en) * | 1973-02-28 | 1976-05-18 | Delmar Chemicals Limited | Novel phthalazinone compounds |
| US4011219A (en) * | 1975-03-28 | 1977-03-08 | Chugai Seiyaku Kabushiki Kaisha | Phthalazine derivatives and salts thereof |
| IE47592B1 (en) * | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
| US4334069A (en) * | 1978-07-24 | 1982-06-08 | Miles Laboratories, Inc. | Chemiluminescent phthalhydrazide-labeled hapten conjugates |
| US4226993A (en) * | 1978-07-24 | 1980-10-07 | Miles Laboratories, Inc. | Amino-functionalized phthalhydrazides |
| US4355165A (en) * | 1978-07-24 | 1982-10-19 | Miles Laboratories, Inc. | Amino-functionalized phthalhydrazide intermediates |
| US4250180A (en) * | 1979-07-16 | 1981-02-10 | Ortho Pharmaceutical Corporation | Method of treating arrhythmia |
| WO1982000641A1 (en) * | 1980-08-25 | 1982-03-04 | Ab Kabivitrum | Peptide substrates for determination of protease activity |
| HU181184B (en) * | 1980-09-12 | 1983-06-28 | Eszakmagyar Vegyimuevek | Composition for replacing kinetine,the effect and membraneactivity of which is similar to citokinine,which composition improves plant productivity,quantity of protein-nitrogen and anion-absorptivity |
| US4440763A (en) * | 1981-03-18 | 1984-04-03 | Block Drug Company, Inc. | Use of 4-aminosalicyclic acid as an anti-inflammatory agent |
| US4665181A (en) * | 1984-05-17 | 1987-05-12 | Pennwalt Corporation | Anti-inflammatory phthalazinones |
| US5391555A (en) * | 1991-11-12 | 1995-02-21 | Miles Inc. | Methods for treating inflammatory bowel disease with leukotriene synthesis inhibitors |
| CH683966A5 (it) * | 1993-02-19 | 1994-06-30 | Limad Marketing Exp & Imp | Composti della classe dei ftalidrazidici come sostanze attive in agenti anti-ipossici e di difesa. |
-
1993
- 1993-02-19 CH CH530/93A patent/CH683965A5/it not_active IP Right Cessation
-
1994
- 1994-02-12 DE DE69419640T patent/DE69419640D1/de not_active Expired - Lifetime
- 1994-02-12 EP EP94102183A patent/EP0617024B1/de not_active Expired - Lifetime
- 1994-02-12 AT AT94102183T patent/ATE182586T1/de active
- 1994-02-18 JP JP6021376A patent/JP2693373B2/ja not_active Expired - Fee Related
-
1995
- 1995-10-23 US US08/551,886 patent/US5543410A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH07179431A (ja) | 1995-07-18 |
| EP0617024A1 (de) | 1994-09-28 |
| JP2693373B2 (ja) | 1997-12-24 |
| CH683965A5 (it) | 1994-06-30 |
| DE69419640D1 (de) | 1999-09-02 |
| US5543410A (en) | 1996-08-06 |
| EP0617024B1 (de) | 1999-07-28 |
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