DE69416103T2 - Verdrängungschromatographisches verfahren und gereinigtes hämoglobin - Google Patents

Verdrängungschromatographisches verfahren und gereinigtes hämoglobin

Info

Publication number
DE69416103T2
DE69416103T2 DE69416103T DE69416103T DE69416103T2 DE 69416103 T2 DE69416103 T2 DE 69416103T2 DE 69416103 T DE69416103 T DE 69416103T DE 69416103 T DE69416103 T DE 69416103T DE 69416103 T2 DE69416103 T2 DE 69416103T2
Authority
DE
Germany
Prior art keywords
hemoglobin
column
admixtures
stage
chromatographic method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69416103T
Other languages
English (en)
Other versions
DE69416103D1 (de
Inventor
Diana Pliura
Diane Wiffen
Salman Ashraf
Anthony Magnin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hemosol Inc
Original Assignee
Hemosol Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA002106612A external-priority patent/CA2106612C/en
Application filed by Hemosol Inc filed Critical Hemosol Inc
Publication of DE69416103D1 publication Critical patent/DE69416103D1/de
Application granted granted Critical
Publication of DE69416103T2 publication Critical patent/DE69416103T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/422—Displacement mode
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials
DE69416103T 1993-09-21 1994-09-20 Verdrängungschromatographisches verfahren und gereinigtes hämoglobin Expired - Fee Related DE69416103T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002106612A CA2106612C (en) 1993-09-21 1993-09-21 Displacement chromatography process
PCT/CA1994/000514 WO1995008574A1 (en) 1993-09-21 1994-09-20 Displacement chromatography process and purified hemoglobin product

Publications (2)

Publication Number Publication Date
DE69416103D1 DE69416103D1 (de) 1999-03-04
DE69416103T2 true DE69416103T2 (de) 1999-08-05

Family

ID=4152343

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69416103T Expired - Fee Related DE69416103T2 (de) 1993-09-21 1994-09-20 Verdrängungschromatographisches verfahren und gereinigtes hämoglobin

Country Status (9)

Country Link
JP (1) JP4057049B2 (de)
KR (1) KR100361894B1 (de)
AT (1) ATE175975T1 (de)
DE (1) DE69416103T2 (de)
DK (1) DK0668877T3 (de)
ES (1) ES2126775T3 (de)
HU (1) HU218159B (de)
RU (1) RU2145873C1 (de)
UA (1) UA35599C2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE112006001012B4 (de) * 2005-04-22 2017-05-18 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) Verfahren für eine auf Massenspektrometrie gerichtete Aufbereitung von Biopolymeren

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013501075A (ja) 2009-08-06 2013-01-10 ジェネンテック， インコーポレイテッド タンパク質精製におけるウイルス除去の改良方法
JP2014503495A (ja) * 2010-11-15 2014-02-13 バイオジェン アイデック インコーポレイテッド 過負荷結合および溶出クロマトグラフィによる選択生成物アイソフォームの富化および濃縮
SI2794635T1 (sl) * 2011-12-22 2018-12-31 F. Hoffmann-La Roche Ag Ionskoizmenjevalna membranska kromatografija
TWI675041B (zh) 2013-05-06 2019-10-21 法商賽諾菲公司 用於純化抗體之連續多步驟方法
TW202128264A (zh) * 2019-09-25 2021-08-01 瑞士商赫孚孟拉羅股份公司 使用經預測之溶離緩衝鹽濃度的陽離子層析法
CN114712894B (zh) * 2022-04-08 2024-04-30 无锡博慧斯生物医药科技有限公司 一种糖化血红蛋白层析柱的活化液、活化方法和应用

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE112006001012B4 (de) * 2005-04-22 2017-05-18 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) Verfahren für eine auf Massenspektrometrie gerichtete Aufbereitung von Biopolymeren

Also Published As

Publication number Publication date
ATE175975T1 (de) 1999-02-15
DK0668877T3 (da) 1999-09-13
RU95112503A (ru) 1996-12-20
HUT72924A (en) 1996-06-28
JP4057049B2 (ja) 2008-03-05
RU2145873C1 (ru) 2000-02-27
DE69416103D1 (de) 1999-03-04
ES2126775T3 (es) 1999-04-01
HU9501479D0 (en) 1995-07-28
JPH08503714A (ja) 1996-04-23
UA35599C2 (uk) 2001-04-16
KR100361894B1 (ko) 2003-05-12
HU218159B (hu) 2000-06-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: HEMOSOL INC., MISSISSAUGA, ONTARIO, CA

8339 Ceased/non-payment of the annual fee