DE69416078T2 - Peptide mit Affinität für Entzündungen und deren radiomarkierte, diagnostische Zusammensetzungen - Google Patents

Peptide mit Affinität für Entzündungen und deren radiomarkierte, diagnostische Zusammensetzungen

Info

Publication number
DE69416078T2
DE69416078T2 DE69416078T DE69416078T DE69416078T2 DE 69416078 T2 DE69416078 T2 DE 69416078T2 DE 69416078 T DE69416078 T DE 69416078T DE 69416078 T DE69416078 T DE 69416078T DE 69416078 T2 DE69416078 T2 DE 69416078T2
Authority
DE
Germany
Prior art keywords
peptide
inflammation
inflammatory
administration
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69416078T
Other languages
English (en)
Other versions
DE69416078D1 (de
Inventor
Yoshitoshi Itaya
Koichi Hanaoka
Yoshifumi Shirakami
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nihon Medi Physics Co Ltd
Original Assignee
Nihon Medi Physics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Medi Physics Co Ltd filed Critical Nihon Medi Physics Co Ltd
Application granted granted Critical
Publication of DE69416078D1 publication Critical patent/DE69416078D1/de
Publication of DE69416078T2 publication Critical patent/DE69416078T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69416078T 1993-10-22 1994-10-20 Peptide mit Affinität für Entzündungen und deren radiomarkierte, diagnostische Zusammensetzungen Expired - Fee Related DE69416078T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP28775293 1993-10-22

Publications (2)

Publication Number Publication Date
DE69416078D1 DE69416078D1 (de) 1999-03-04
DE69416078T2 true DE69416078T2 (de) 1999-05-27

Family

ID=17721307

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69416078T Expired - Fee Related DE69416078T2 (de) 1993-10-22 1994-10-20 Peptide mit Affinität für Entzündungen und deren radiomarkierte, diagnostische Zusammensetzungen

Country Status (9)

Country Link
US (1) US5821330A (de)
EP (1) EP0649857B1 (de)
KR (1) KR100316376B1 (de)
AT (1) ATE175976T1 (de)
AU (1) AU675166B2 (de)
CA (1) CA2134051A1 (de)
DE (1) DE69416078T2 (de)
DK (1) DK0649857T3 (de)
ES (1) ES2126695T3 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5989519A (en) * 1992-03-13 1999-11-23 Diatide, Inc. Technetium-99m labeled peptides for imaging inflammation
JPH07504902A (ja) * 1992-03-13 1995-06-01 ダイアタイド・インコーポレイテッド 炎症造影用のテクネチウム−99m標識ペプチド
CA2165228A1 (en) * 1994-12-27 1996-06-28 Yoshitoshi Itaya Metal chelate forming peptides and use thereof
DE19514088A1 (de) * 1995-04-13 1996-10-17 Deutsches Krebsforsch Konjugat zur Behandlung von Entzünduns-, Infektions- und/oder Hauterkrankungen
AU757554B2 (en) * 1998-02-11 2003-02-27 Bracco International B.V. Angiogenesis targeting molecules
AU2001232845A1 (en) * 2000-01-21 2001-07-31 Mallinckrodt, Inc. Methods for incorporating metal chelators at carboxyl-terminal site of peptides
AU2001234478A1 (en) * 2000-01-21 2001-07-31 Mallinckrodt, Inc. Chelating agents and method for their use as tandem metal chelators and hydrophilic spacers for medical diagnosis and therapy
AU2001236485A1 (en) * 2000-01-21 2001-07-31 Mallinckrodt, Inc. Novel orthogonally protected amino acid chelators for biomedical applications
US8263739B2 (en) 2000-06-02 2012-09-11 Bracco Suisse Sa Compounds for targeting endothelial cells, compositions containing the same and methods for their use
EP1289565B1 (de) 2000-06-02 2015-04-22 Bracco Suisse SA Arzneimitteln zur zielgerichtung von endothelzellen
KR100882751B1 (ko) * 2002-05-08 2009-02-09 재단법인서울대학교산학협력재단 키토산에 특이적으로 부착하는 올리고 펩타이드
TW200505934A (en) * 2003-03-26 2005-02-16 Nihon Mediphysics Co Ltd Compound having affinity with calcified tissue

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62153300A (ja) * 1985-12-26 1987-07-08 Teijin Ltd ヒト免疫グロブリンGFc領域蛋白質およびその製造方法
JP2515357B2 (ja) * 1986-01-16 1996-07-10 ザ・ジェネラル・ホスピタル・コ−ポレ−ション 炎症の診断方法および治療方法
US4926869A (en) * 1986-01-16 1990-05-22 The General Hospital Corporation Method for the diagnosis and treatment of inflammation
CA1266344A (en) * 1986-02-14 1990-02-27 Miki Kurami High molecular compounds having amino groups, and their utilization
EP0584421A1 (de) * 1992-08-21 1994-03-02 Cécile Casterman Immunoglobuline ohne Leichtkette

Also Published As

Publication number Publication date
ES2126695T3 (es) 1999-04-01
CA2134051A1 (en) 1995-04-23
DK0649857T3 (da) 1999-09-13
AU7597994A (en) 1995-05-11
EP0649857A1 (de) 1995-04-26
ATE175976T1 (de) 1999-02-15
KR100316376B1 (ko) 2002-02-19
AU675166B2 (en) 1997-01-23
EP0649857B1 (de) 1999-01-20
DE69416078D1 (de) 1999-03-04
US5821330A (en) 1998-10-13
KR950011467A (ko) 1995-05-15

Similar Documents

Publication Publication Date Title
DE69416078D1 (de) Peptide mit Affinität für Entzündungen und deren radiomarkierte, diagnostische Zusammensetzungen
Gregory et al. The primary structure of human urogastrone
Steiner et al. The spontaneous reoxidation of reduced beef and rat proinsulins.
Takeya et al. Primary structure of H2-proteinase, a non-hemorrhagic metalloproteinase, isolated from the venom of the habu snake, Trimeresurus flavoviridis
US4079127A (en) Thymosin alpha 1
Press et al. The amino acid sequences of the Fd fragments of two human γ 1 heavy chains
ATE325625T1 (de) Technetium-99m markierte peptide zur diagnostischen bilderzeugung von entzündungen
DE69201441T2 (de) Erreger der mysteriösen schweinekrankheit,impfstoff-zusammensetzungen und diagnose kits.
FI946066A (fi) Hepatiitti-C viruksen genotyyppien uudet sekvenssit ja niiden käyttö terapeuttisina ja diagnostisina aineina
ATE108662T1 (de) Antimikrobielle peptide, zusammensetzungen, die diese enthalten, und verwendungen daraus.
CA2016235A1 (en) Labeled chemotactic peptides to image focal sites of infection or inflammation
Groskopf et al. Studies on the active center of human plasmin: partial amino acid sequence of a peptide containing the active center serine residue
CA2153789A1 (en) Biologically active tgf-.beta.1 and tgf-.beta.2 peptides
ATE78040T1 (de) Oligopeptide sowie zwischenprodukte und verfahren zu ihrer herstellung.
DK0831938T3 (da) Radiomærkede peptidsammensætninger til stedspecifik målsögninger
ATE321774T1 (de) An aminosaeure angereicherte speicherproteine, insbesondere an lysin angereicherte mais-gamma- zeine, und diese exprimierende pflanzen
DE69419919D1 (de) Technetium-99m markierte peptide zur bilderzeugung der entzuendung
EP1502949A4 (de) Antimikrobielles polypeptid und nutzung davon
Butler et al. Chemical studies on the cyanogen bromide peptides of rat skin collagen. Amino acid sequence of α1-CB4
Gall et al. The covalent structure of a human γG-immunoglobulin. IV. The interchain disulfide bonds
DE69033453D1 (de) Rekombinante Polypeptide und Peptide, dafür kodierende Nukleinsäuren und ihre Verwendung in der Tuberkulose-Diagnose
EP1950221A3 (de) Genomsequenzen von exportierten Polypeptiden aus Mykobakterien, diese enthaltende Vektoren und deren Anwendung in der Diagnostik und Prävention von Tuberkulose
ATE181961T1 (de) Neue wasserlösliche polypeptide mit hoher affinität für alpha- und beta- interferone
Milstein et al. Disulphide bridges of the heavy chain of human immunoglobulin G2
JPH03503178A (ja) 改変形質転換成長因子αオリゴペプタイド及びその医薬組成物

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee