DE69419919D1 - Technetium-99m markierte peptide zur bilderzeugung der entzuendung - Google Patents

Technetium-99m markierte peptide zur bilderzeugung der entzuendung

Info

Publication number
DE69419919D1
DE69419919D1 DE69419919T DE69419919T DE69419919D1 DE 69419919 D1 DE69419919 D1 DE 69419919D1 DE 69419919 T DE69419919 T DE 69419919T DE 69419919 T DE69419919 T DE 69419919T DE 69419919 D1 DE69419919 D1 DE 69419919D1
Authority
DE
Germany
Prior art keywords
compositions
technetium
methods
radiolabel
inflammation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69419919T
Other languages
English (en)
Other versions
DE69419919T2 (de
Inventor
Richard Dean
Brian Moyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CIS Bio International SA
Original Assignee
Diatide Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diatide Inc filed Critical Diatide Inc
Publication of DE69419919D1 publication Critical patent/DE69419919D1/de
Application granted granted Critical
Publication of DE69419919T2 publication Critical patent/DE69419919T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
DE69419919T 1993-06-07 1994-05-25 Technetium-99m markierte peptide zur bilderzeugung der entzuendung Expired - Fee Related DE69419919T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/073,577 US5561220A (en) 1991-02-08 1993-06-07 Technetium-99m labeled peptides for imaging inflammation
PCT/US1994/005895 WO1994028942A1 (en) 1993-06-07 1994-05-25 TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING INFLAMMATION

Publications (2)

Publication Number Publication Date
DE69419919D1 true DE69419919D1 (de) 1999-09-09
DE69419919T2 DE69419919T2 (de) 2000-04-20

Family

ID=22114537

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69419919T Expired - Fee Related DE69419919T2 (de) 1993-06-07 1994-05-25 Technetium-99m markierte peptide zur bilderzeugung der entzuendung

Country Status (13)

Country Link
US (2) US5561220A (de)
EP (1) EP0702570B1 (de)
JP (1) JP2941060B2 (de)
AT (1) ATE182795T1 (de)
AU (1) AU684294B2 (de)
CA (1) CA2164707C (de)
DE (1) DE69419919T2 (de)
DK (1) DK0702570T3 (de)
ES (1) ES2135585T3 (de)
GR (1) GR3031351T3 (de)
SG (1) SG44702A1 (de)
WO (1) WO1994028942A1 (de)
ZA (1) ZA943984B (de)

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US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
US6107459A (en) * 1991-02-08 2000-08-22 Diatide, Inc. Technetium-99m labeled peptides for diagnostic imaging
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
US6019958A (en) * 1991-02-08 2000-02-01 Diatide, Inc. Technetium-99m labeled peptides for imaging inflammation
US5645815A (en) * 1991-02-08 1997-07-08 Diatide, Inc. Radiolabled compounds for thrombus imaging
US5993775A (en) * 1991-11-27 1999-11-30 Diatide, Inc. Radioactively labeled peptides comprising a single thiol moiety
DE69332879T2 (de) * 1992-03-13 2004-02-19 Diatide, Inc. Technetium-99-markierte peptide zur visualisierung vom entzuendungen
US5989519A (en) * 1992-03-13 1999-11-23 Diatide, Inc. Technetium-99m labeled peptides for imaging inflammation
US5508020A (en) * 1992-06-05 1996-04-16 Diatech, Inc. Technetium-99M labeled peptides for imaging
US5620675A (en) 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
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AU1171795A (en) * 1993-11-05 1995-05-23 Repligen Corporation Novel modified pf4 compositions and methods of use
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
CA2165228A1 (en) * 1994-12-27 1996-06-28 Yoshitoshi Itaya Metal chelate forming peptides and use thereof
US5753206A (en) * 1995-06-07 1998-05-19 Immunomedics, Inc. Radiometal-binding analogues of luteinizing hormone releasing hormone
WO1998002192A1 (en) 1996-07-12 1998-01-22 Immunomedics, Inc. Radiometal-binding peptide analogues
US6314314B1 (en) 1999-01-14 2001-11-06 Seth J. Karp Method for locating an internal bleeding site in a human body
US6409987B1 (en) 1999-04-07 2002-06-25 Intimax Corporation Targeted agents useful for diagnostic and therapeutic applications
US6254852B1 (en) 1999-07-16 2001-07-03 Dupont Pharmaceuticals Company Porous inorganic targeted ultrasound contrast agents
KR20050097494A (ko) * 2002-11-25 2005-10-07 아테뉴온, 엘엘씨 혈관신생, 세포 이동, 세포 침투 및 증식을 저해하는펩타이드, 그것의 조성물 및 그것의 용도
KR20060130588A (ko) * 2003-11-18 2006-12-19 아테뉴온, 엘엘씨 우로키나제의 아미노 말단 단편에 결합하는 항체 및/또는이의 접합체, 조성물 및 이의 용도
US20060024229A1 (en) * 2004-07-29 2006-02-02 Seth Karp Method and product for locating an internal bleeding site
CA2680606C (en) 2006-03-29 2014-08-05 Wayne State University Liposomal nanoparticles and other formulations of fenretinide for use in therapy and drug delivery
US20080167544A1 (en) * 2006-12-01 2008-07-10 Cold Spring Diagnostics, Inc. Compositions And Methods For Locating An Internal Bleeding Site
WO2008073312A2 (en) * 2006-12-08 2008-06-19 Attenuon, Llc Urokinase-type plasminogen activator receptor epitope, monoclonal antibodies derived therefrom and methods of use thereof

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US4385046A (en) * 1980-12-15 1983-05-24 Minnesota Mining And Manufacturing Company Diagnostic radio-labeled polysaccharide derivatives
US4427646A (en) * 1981-04-02 1984-01-24 Research Corporation Use of radiolabeled peptide derived from crosslinked fibrin to locate thrombi in vivo
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US4472509A (en) * 1982-06-07 1984-09-18 Gansow Otto A Metal chelate conjugated monoclonal antibodies
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US4673562A (en) * 1983-08-19 1987-06-16 The Children's Medical Center Corporation Bisamide bisthiol compounds useful for making technetium radiodiagnostic renal agents
ATE66469T1 (de) * 1985-01-14 1991-09-15 Neorx Corp Metall-radionuklid markiertes protein fuer diagnose und therapie.
US4830847A (en) * 1985-06-28 1989-05-16 The Procter & Gamble Company Diphosphonate-derivatized macromolecules
US4844895A (en) * 1985-11-01 1989-07-04 New York University Composition containing a peptide fragment of platelet factor four and method for restoring suppressed immune responses
US4861869A (en) * 1986-05-29 1989-08-29 Mallinckrodt, Inc. Coupling agents for joining radionuclide metal ions with biologically useful proteins
US4729525A (en) * 1986-12-12 1988-03-08 Trw Vehicle Safety Systems Inc. Seat belt retractor with electrically actuatable locking mechanism
DE3889956T2 (de) * 1987-03-26 1994-12-22 Neorx Corp Metall-Radionuklid-markierte Proteine und Glykoproteine zur Diagnose und Therapie.
US4952393A (en) * 1987-04-02 1990-08-28 The General Hospital Corporation Organ infarct imaging with technetium labelled glucarate
DE3884703D1 (de) * 1987-07-23 1993-11-11 Bayer Ag Halogenierte Thiadiazolyl-oxyessig-säureamide, Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung als Herbizide.
US5266562A (en) * 1987-11-19 1993-11-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Anti-inflammatory agents
US4857508A (en) * 1987-12-03 1989-08-15 Monsanto Company Novel platelet-aggregation inhibitor peptide derivatives
JP2547263B2 (ja) * 1987-12-10 1996-10-23 ラ・ジョラ・キャンサー・リサーチ・ファウンデーション 立体配座的に安定化された細胞付着ペプチド
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US5198424A (en) * 1989-03-08 1993-03-30 Board Of Regents Of The University Of Oklahoma Functionally active selectin-derived peptides
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DE3914703A1 (de) * 1989-05-04 1990-11-08 Steinhardt Lothar Abflussmengenregler
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Also Published As

Publication number Publication date
GR3031351T3 (en) 2000-01-31
US5561220A (en) 1996-10-01
EP0702570A1 (de) 1996-03-27
AU684294B2 (en) 1997-12-11
ATE182795T1 (de) 1999-08-15
CA2164707C (en) 2001-01-16
ZA943984B (en) 1995-01-16
SG44702A1 (en) 1997-12-19
DK0702570T3 (da) 2000-03-06
EP0702570B1 (de) 1999-08-04
US5714579A (en) 1998-02-03
JPH08509001A (ja) 1996-09-24
ES2135585T3 (es) 1999-11-01
JP2941060B2 (ja) 1999-08-25
CA2164707A1 (en) 1994-12-22
AU7045394A (en) 1995-01-03
DE69419919T2 (de) 2000-04-20
WO1994028942A1 (en) 1994-12-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: CIS BIO INTERNATIONAL, GIF-SUR-YVETTE, FR

8328 Change in the person/name/address of the agent

Representative=s name: DF-MP, 80333 MUENCHEN

8339 Ceased/non-payment of the annual fee